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Moacir Wajner
Bolsista de Produtividade em Pesquisa do CNPq - Nível 1A

Possui graduação em Medicina pela Faculdade de Medicina pela Universidade Federal do Rio Grande do Sul (1973), residência em Medicina Interna pelo Hospital de Clínicas de Porto Alegre, doutorado em Ciencias Basicas pela Universidade de Newcastle Upon Tyne, Inglaterra (1982) e pós-doutorados em erros inatos do metabolismo pelas Universidade de Londres, Inglaterra (1986-1987), Heidelberg, Alemanha (1993) e New Haven, USA (1995). Atualmente é professor titular do Departamento de Bioquímica da Universidade Federal do Rio Grande do Sul, communicating editor do Journal of Inherited Metabolic Disease, membro titular da Academia Brasileira de Ciências, Revisor de mais de duas dezenas de periódicos estrangeiros de circulação internacional na área de bioquímica, genética e neurociências.Tem experiência na área de Bioquímica, com ênfase em Erros Inatos do Metabolismo em seres humanos e em modelos animais experimentais, investigando principalmente os mecanismos neurotóxicos de ácidos orgânicos acumulados em algumas acidemias orgânicas e o papel dos mesmos sobre o metabolismo energético, as oxidações biológicas, a neurotransmissão glutamatérgica e o comportamentos cognitivo e convulsiivante.
(Texto informado pelo autor)

Última atualização do currículo em 18/01/2012
Endereço para acessar este CV:
http://lattes.cnpq.br/2714257711512999
Dados pessoais
NomeMoacir Wajner
Nome em citações bibliográficasWAJNER, M.;Wajner, Moacir
SexoMasculino
Endereço profissionalUniversidade Federal do Rio Grande do Sul, Instituto de Ciencias Basicas da Saude.
Av. Ramiro Barcelos, 2600 Anexo
Santana
90035-003 - Porto Alegre, RS - Brasil
Telefone: (051) 33085571 Fax: (051) 33085540

Formação acadêmica/Titulação
1993 - 1993Pós-Doutorado .
Ruprecht-Karls-Universität Heidelberg.
1986 - 1987Pós-Doutorado .
University of London.
Bolsista do(a): Conselho Nacional de Desenvolvimento Científico e Tecnológico ,CNPq ,Brasil .
Grande área: Ciências Biológicas / Área: Bioquímica / Subárea: Metabolismo e Bioenergética.
1979 - 1982Doutorado em Phd Em Ciencias Basicas .
Universidade de Newcastle Upon Tyne.
Título: The effect of human alpha-fetoprotein on cell -mediated and humoral immunity during pregnancy, Ano de Obtenção: 1982.
Orientador: Surrinder Papiha.
Bolsista do(a): Coordenação de Aperfeiçoamento de Pessoal de Nível Superior ,CAPES ,Brasil .
1974 - 1975Especialização em Faculdade de Medicina Residência Em Medicina Inter .
Universidade Federal do Rio Grande do Sul, UFRGS, Brasil.
1968 - 1973Graduação em Faculdade de Medicina .
Universidade Federal do Rio Grande do Sul, UFRGS, Brasil.

Formação complementar
1974 - 1975Residência Médica em Medicina Interna. (Carga horária: 4360h).
Hospital de Clínicas de Porto Alegre.

Atuação profissional
Universidade Federal do Rio Grande do Sul, UFRGS, Brasil.
Vínculo institucional
1997 - Atual Vínculo: Servidor público ou celetista, Enquadramento Funcional: Professor Titular, Carga horária: 40, Regime: Dedicação exclusiva.
Vínculo institucional
1982 - 1997 Vínculo: Servidor público ou celetista, Enquadramento Funcional: Professor Adjunto, Carga horária: 40, Regime: Dedicação exclusiva.
Vínculo institucional
1980 - 1982 Vínculo: Servidor público ou celetista, Enquadramento Funcional: Professor Assistente, Carga horária: 40, Regime: Dedicação exclusiva.
Atividades
8/1982 - AtualOutras atividades técnico-científicas , Instituto de Biociências, Departamento de Bioquímica.
Atividade realizada
Pesquisador.
8/1982 - AtualOutras atividades técnico-científicas , Instituto de Biociências, Departamento de Bioquímica.
Atividade realizada
Professor de Pós-Graduação.
3/1982 - AtualEnsino, Ciências Biológicas (Bioquímica), Nível: Pós-Graduação.
Disciplinas ministradas
Seminário estudos metabólicos em acidemias orgânicas
Seminário estudo dos mecanismos neurotóxicos envolvidos nas acidemias orgânicas
12/1980 - AtualPesquisa e desenvolvimento , Instituto de Ciencias Basicas da Saude, Departamento de Bioquímica.
Linhas de pesquisa
NEURODEGENERAÇÃO EM DISTÚRBIOS DO METABOLISMO INTERMEDIARIO
ESTUDOS DOS MECANISMOS DE NEUROTOXICIDADE DE ÁCIDOS ORGÂNICOS ACUMULADOS EM VÁRIAS ACIDEMIAS ORGÂNICAS
12/1980 - AtualEnsino, Faculdade de Medicina, Nível: Graduação.
Disciplinas ministradas
Atividades de Integração Básico Clínica
Bioquímica Médica II
Bioquímica Médica III
12/1980 - AtualOutras atividades técnico-científicas , Instituto de Biociências, Departamento de Bioquímica.
Atividade realizada
Professor de graduação.
12/1988 - 2002Extensão universitária , Hospital de Clínicas de Porto Alegre, Serviço de Genética Médica.
Atividade de extensão realizada
DOCENTE E REGENTE DE DISCIPLINAS DE GRADUACAO E POS-GRADUACAO; ORIENTADOR DE BOLSISTAS DE GRADUACAO E POS-GRADUACAO. IMPLEMENTAÇÃO DE LABORATÓRIO DE DETECÇÃO DE METABÓLITOS ACUMULADOS EM ERROS INATOS DO METABOLISMO..
6/1997 - 8/1998Direção e administração, Instituto de Ciencias Basicas da Saude, Instituto de Ciências Básicas da Saúde.
Cargo ou função
Diretor do Instituto de Ci~encias Básicas da Saúde.
10/1988 - 6/1997Estágios Reitoria.
Estágio realizado
MEMBRO DA COMISSAO DE PROTECAO RADIOLOGICA/UFRGS; MEMBRO DA COMISSAO DE INTERCAMBIO INTERNACIONAL - UFRGS..
11/1993 - 11/1995Direção e administração, Curso de Pós Grtaduação Em Ciências Biológicas Bioquímica, Departamento de Bioquímica.
Cargo ou função
Coordenador de Curso de Pós-Graduação.
3/1989 - 3/1993Direção e administração, Instituto de Biociências, Departamento de Bioquímica.
Cargo ou função
CHEFE DO DEPARTAMENTO DE BIOQUIMICA DO INSTITUTO DE BIOCIENCIAS; COLEGIADO DO CURSO DE POS-GRADUACAO EM CIENCIAS BIOLOGICAS - BIOQUIMICA; COLEGIADO DO DEPARTAMENTO DE BIOQUIMICA..
09/1984 - 09/1986Direção e administração, .
Cargo ou função
COORDENADOR DO CURSO DE POS-GRADUACAO EM CIENCIAS BIOLOGICAS: BIOQUIMICA - UFRGS..

Linhas de Pesquisa
1. NEURODEGENERAÇÃO EM DISTÚRBIOS DO METABOLISMO INTERMEDIARIO
Objetivos: Os objetivos dessa linha é o de investigar o efeito de metabólitos acumulados emvários erros inatos do metabolismo sobre sistemas críticos ao funcionamento normal do cérebro.
Palavras-chave: oxidative stress; acidemias orgânicas; a-amino acids accumulating; ácidos graxos.
2. ESTUDOS DOS MECANISMOS DE NEUROTOXICIDADE DE ÁCIDOS ORGÂNICOS ACUMULADOS EM VÁRIAS ACIDEMIAS ORGÂNICAS
Objetivos: Estudar o efeito de ácidos orgânicos que se acumulam em váriosdistúrbios hereditários metabólicos sobre o comportamento cognitivo e convulsivante, bem como sobre sistemas críticos para o funcionamento normal do cérebro, tais como o metabolismo energético, a neurotransmissão e o redox (as oxidações biológicas/estresse oxidativo).
Palavras-chave: acidemias orgânicas.

Membro de corpo editorial
1988 - Atual Periódico: Journal of Inherited Metabolic Disease
2009 - Atual Periódico: Asociación Colombiana de Genetica Humana
2009 - Atual Periódico: Molecular and Cellular Biochemistry

Revisor de periódico
2006 - Atual Periódico: Bioorganic & Medicinal Chemistry
2004 - Atual Periódico: Neuroscience Research
1988 - Atual Periódico: Journal of Inherited Metabolic Disease
2007 - Atual Periódico: BMC Medical Genetics (1471-2350)
2006 - Atual Periódico: Neurobiology of Disease
1998 - Atual Periódico: Journal of Neurochemistry (0022-3042)
2006 - Atual Periódico: Journal of Food Biochemistry
2003 - Atual Periódico: FEBS Letters
2005 - Atual Periódico: Molecular Genetics and Metabolism
2002 - Atual Periódico: Biochimica et Biophysica Acta. Molecular Basis of Disease
2005 - Atual Periódico: Journal of the Neurological Sciences
2005 - Atual Periódico: The Journal of Neuroscience (0270-6474)
2005 - Atual Periódico: Brain Research
2007 - Atual Periódico: International Journal of Immunopharmacology
2007 - Atual Periódico: Brazilian Journal of Medical and Biological Research
2007 - Atual Periódico: Pediatric Research (0031-3998)
2007 - Atual Periódico: Bioorganic & Medicinal Chemistry (0968-0896)
2008 - Atual Periódico: Cellular and Molecular Biology
2008 - Atual Periódico: Experimental Neurology. Supplement
2006 - Atual Periódico: Experimental Brain Research
2008 - Atual Periódico: Human Molecular Genetics
2008 - Atual Periódico: Neuropediatrics
2008 - Atual Periódico: Neuroscience
2008 - Atual Periódico: Clinical Genetics
2008 - Atual Periódico: Brain (London)
2008 - Atual Periódico: Fundamental & Clinical Pharmacology
2009 - Atual Periódico: American Journal of Medical Genetics. Part A
2009 - Atual Periódico: Brain Research Bulletin
2009 - Atual Periódico: Journal of Pharmacy and Pharmacology
2010 - Atual Periódico: Nueroscience Letters

Áreas de atuação
1. Grande área: Ciências Biológicas / Área: Bioquímica / Subárea: Metabolismo e Bioenergética.
2. Grande área: Ciências Biológicas / Área: Bioquímica / Subárea: Biologia Molecular / Especialidade: Erros Inatos do Metabolismo.
3. Grande área: Ciências Biológicas / Área: Bioquímica / Subárea: Metabolismo e Bioenergética / Especialidade: Estudo dos Ácidos Org Ânicos Sobre o Metabolismo Energético.
4. Grande área: Ciências Biológicas / Área: Bioquímica / Subárea: Enzimologia / Especialidade: Estudo da Neurotoxicidade dos Ácidos Orgânicos Acumulados nas Acidemias Orgânicas.
5. Grande área: Ciências Biológicas / Área: Bioquímica / Subárea: Química de Macromoléculas / Especialidade: Estudo do Efeito de Ácidos Orgânicos Sobre o Sistema Glutamatérgico Em Cérebro de Rat.
6. Grande área: Ciências Biológicas / Área: Genética / Subárea: Genética Humana e Médica / Especialidade: Diagnóstico de Erros Inatos do Metabolismo de Aminoácidos e de Ácidos Orgãnicos.

Idiomas
Inglês Fala Bem, Lê Bem, Escreve Bem.
Espanhol Fala Razoavelmente, Lê Bem, Escreve Pouco.


Produção em C,T & A
Produção bibliográfica
Citações
Web of Science
Total de trabalhos408Total de citações34505Fator H30
wajner m  Data: 16/11/2011
Artigos completos publicados em periódicos
1. Busanello, Estela Natacha Brandt ; Amaral, Alexandre Umpierrez ; Tonin, Anelise Miotti ; Grings, Mateus ; Moura, Alana Pimentel ; Eichler, Paula ; VARGAS, Carmen Regla ; Wajner, Moacir . Experimental evidence that pristanic acid disrupts mitochondrial homeostasis in brain of young rats. Journal of Neuroscience Research, v. 90, p. 597-605, 2012.
2. Ribeiro, César Augusto João ; Hickmann, Fernanda Hermes ; Wajner, Moacir . Neurochemical evidence that 3-methylglutaric acid inhibits synaptic Na+,K+-ATPase activity probably through oxidative damage in brain cortex of young rats. International Journal of Developmental Neuroscience, v. 29, p. 1-7, 2011.
3. VIEGAS, Carolina Maso ; BUSANELLO, E. N. B. ; TONIN, Anelise ; MOURA, A P ; GRINGS, M. ; RITTER, L. ; SCHUCK, Patrícia Fernanda ; FERREIRA, Gustavo C ; SITTA, Angela A ; VARGAS, C. R. ; WAJNER, M. . Dual mechanism of brain damage induced in vivo by the major metabolites accumulating in hyperornithinemia hyperammonemia homocitrullinuria syndrome. Brain Research, v. 1369, p. 235-244, 2011.
4. Wajner, Moacir ; Goodman, Stephen I. . Disruption of mitochondrial homeostasis in organic acidurias: insights from human and animal studies. Journal of Bioenergetics and Biomembranes, v. 43, p. 31-38, 2011.
5. LEIPNITZ, Guilhian ; Amaral, Alexandre Umpierrez ; Fernandes, Carolina Gonçalves ; SEMINOTTI, Bianca ; Zanatta, Ângela ; Knebel, Lisiane Aurélio ; VARGAS, Carmen Regla ; Wajner, Moacir . Pristanic acid promotes oxidative stress in brain cortex of young rats: A possible pathophysiological mechanism for brain damage in peroxisomal disorders. Brain Research, v. 1382, p. 259-265, 2011.
6. Melo, Daniela R. ; Kowaltowski, Alicia J. ; Wajner, Moacir ; Castilho, Roger F. . Mitochondrial energy metabolism in neurodegeneration associated with methylmalonic acidemia. Journal of Bioenergetics and Biomembranes, v. 43, p. 39-46, 2011.
7. SEMINOTTI, Bianca ; Knebel, Lisiane Aurélio ; Fernandes, Carolina Gonçalves ; Amaral, Alexandre Umpierrez ; da Rosa, Mateus Struecker ; Eichler, Paula ; LEIPNITZ, Guilhian ; Wajner, Moacir . Glycine intrastriatal administration induces lipid and protein oxidative damage and alters the enzymatic antioxidant defenses in rat brain. Life Sciences (1973), v. 89, p. 276-281, 2011.
8. FERNANDES, C. G. ; Borges, C. G. ; SEMINOTTI, Bianca ; AMARAL, A. U. ; KNEBEL, L. A. ; Eichler, P ; de OLIVEIRA, A.B. ; LEPNITZ, G. ; WAJNER, M. . Experimental evidence that methylmalonic acid provokes oxidative damage and compromises antioxidant defenses in nerve terminal and striatum of young rats. Cellular and Molecular Neurobiology, v. 31, p. 775-785, 2011.
9. BUSANELLO, E. N. B. ; VIEGAS, C M ; Tonin, AM ; GRINGS, M. ; MOURA, A P ; de OLIVEIRA, A.B. ; Eichler, P ; WAJNER, M. . Neurochemical evidence that pristanic acid impairs energy production and inhibits synaptic N+,K+-ATPase activity in brain of young rats. Neurochemical Research, v. 36, p. 1101-1107, 2011.
10. RIBAS, G. S. ; SITTA, A ; WAJNER, M. ; VARGAS, C. R. . Oxidative stress in phenylketonuria: what is the evidence?. Cellular and Molecular Neurobiology, v. 31, p. 653-662, 2011.
11. Vanzin, Camila Simioni ; Biancini, Giovana Brondani ; SITTA, Angela ; Wayhs, Carlos Alberto Yasin ; Pereira, Izabela Netto ; Rockenbach, Francieli ; Garcia, Solange Cristina ; WYSE, Angela Terezinha de Souza ; Schwartz, Ida Vanessa Doederlein ; Wajner, Moacir ; VARGAS, Carmen Regla . Experimental evidence of oxidative stress in plasma of homocystinuric patients: A possible role for homocysteine. Molecular Genetics and Metabolism (Print), v. 104, p. 112-117, 2011.
12. Ribas, Graziela S. ; SITTA, Angela ; Wajner, Moacir ; Vargas, Carmen R. . Oxidative Stress in Phenylketonuria: What is the Evidence?. Cellular and Molecular Neurobiology, v. 31, p. 653-662, 2011.
13. FERREIRA, A. G. K. ; D.D. LIMA ; DELWING, Debora ; Mackendanz V. ; TAGLIARI, Bárbara ; Kolling, J. ; SCHUCK, Patricia Fernanda ; WAJNER, M. ; WYSE, Â. T. S. . Proline impairs energy metabolism in cerebral cortex of young rats. Metabolic Brain Disease, v. 25, p. 161-168, 2010.
14. FERNANDES, C. G. ; LEIPNITZ, Guilhian ; SEMINOTTI, Bianca ; AMARAL, A. U. ; ZANATTA, A. ; VARGAS, Carmen ; DUTRAFILHO, Carlos S ; WAJNER, M. . Experimental evidence that phenylalanine provokes oxidative estress in hippocampus and cerebral cortex of developing rats. Cellular and Molecular Neurobiology, v. 30, p. 317-326, 2010.
15. Quincozes-Santos, André ; ROSA, Rafael Borba ; LEIPNITZ, Guilhian ; Souza, Daniela Fraga ; SEMINOTTI, Bianca ; Wajner, Moacir ; Gonçalves, Carlos Alberto . Induction of S100B secretion in C6 astroglial cells by the major metabolites accumulating in glutaric acidemia type I. Metabolic Brain Disease, v. 25, p. 191-198, 2010.
16. Marjan Steenweg ; WAJNER, M. ; SALOMONS, G. S. . An overview of L-2-hydroxyglutarate dehydrogenase (L2HGDH) variants: a genotype-phenotype study. Human Mutation, v. 31, p. 380-390, 2010.
17. AMARAL, A. U. ; LEIPNITZ, Guilhian ; FERNANDES, C. G. ; SEMINOTTI, Bianca ; SCHUCK, P. ; WAJNER, M. . alpha-ketoisocaproic acid and leucine provoke mitochondrial bioenergetic dysfunction in rat brain. Brain Research, v. 1324, p. 75-84, 2010.
18. Ribas GC ; Manfredini, V. ; MARI, Jurema F de ; Wayhs, CY ; VANZIN, C.S. ; BIANCINI, G.B. ; SITTA, Â. ; DEON, Marion ; WAJNER, M. ; VARGAS, C. R. . Reduction of lipid and protein damage in patients with disorders of propionate metabolism under treatment: a possible protective role of l-carnitine supplementation.. International Journal of Developmental Neuroscience, v. 28, p. 127-132, 2010.
19. Manfredini, V. ; VANZIN, C.S. ; BIANCINI, G.B. ; Dalvesco, A ; DEON, Marion ; Biasi, Lidiana ; Treméa, Roberta ; WAJNER, M. ; VARGAS, C. . Simvastatin treatment prevents oxidative damage to DNA in whole blood leukocytes of dyslipidemic type 2 diabetic patients. Cell Biochemistry and Function, v. 28, p. 360-366, 2010.
20. Pierozan, Paula ; ZAMONER, Ariane ; Krombauer Soska, Ângela ; Bristot Silvestrin, Roberta ; Oliveira Loureiro, Samanta ; HEIMFARTH, Luana ; Mello e Souza, Tadeu ; Wajner, Moacir ; Pessoa-Pureur, Regina . Acute intrastriatal administration of quinolinic acid provokes hyperphosphorylation of cytoskeletal intermediate filament proteins in astrocytes and neurons of rats. Experimental Neurology, v. 224, p. 188-196, 2010.
21. LEIPNITZ, Guilhian ; SILVA, L. B. ; FERNANDES, C. G. ; SEMINOTTI, B ; AMARAL, A. U. ; DUTRA FILHO, Carlos Severo ; WAJNER, M. . D-serine administration provokes lipid oxidation and decreases the antioxidant defenses in rat striatum. International Journal of Developmental Neuroscience, v. 28, p. 297-301, 2010.
22. TONIN, Anelise ; FERREIRA, Gustavo C ; GRINGS, M. ; VIEGAS, Carolina Maso ; BUSANELLO, E. N. B. ; AMARAL, Alexandre ; ZANATTA, A. ; SCHUCK, Patrícia Fernanda ; WAJNER, M. . Disturbance of mitochondrial energy homeostasis caused by the metabolites accumulating in LCHAD and MTP deficiences in rat brain. Life Sciences (1973), v. 22, p. 825-831, 2010.
23. BUSANELLO, E. N. B. ; MOURA, A P ; VIEGAS, Carolina Maso ; ZANATTA, A. ; FERREIRA, Gustavo C ; SCHUCK, Patrícia Fernanda ; Wajner, Moacir . Neurochemichal evidence that glycine induces bioenergetical dysfunction. Neurochemistry International, v. 56, p. 948-954, 2010.
24. Tonin, AM ; GRINGS, M. ; BUSANELLO, E. N. B. ; MOURA, A P ; FERREIRA, Gustavo C ; VIEGAS, Carolina Maso ; FERNANDES, C. G. ; SCHUCK, Patrícia Fernanda ; WAJNER, M. . Long-chain 3-hydroxy fatty acids accumulating in LCHAD and MTP deficineces induce oxidative stress in rat brain. Neurochemistry International, v. 56, p. 930-936, 2010.
25. MORAES, Tarsila B. ; ZANIN, F.R. ; da Rosa A ; de Oliveira A ; J, Coelho ; Petrillo F ; WAJNER, M. ; DUTRA-FILHO, C. S. . Lipoic acid prevents oxidative stress in vitro and in vivo by an acute hyperohenylalaninemia chemically-induced in rat brain. Journal of the Neurological Sciences, v. 292, p. 89-95, 2010.
26. Pederzolli, Carolina Didonet ; Mescka, Caroline Paula ; Magnusson, Alessandra Selinger ; Deckmann, Kátia Bueno ; Souza Streck, Evelise ; Sgaravatti, Ângela Malysz ; SGARBI, Mirian Bonaldi ; Wyse, Angela T. S. ; Wannmacher, Clovis M. D. ; Wajner, Moacir ; Dutra-Filho, Carlos S. . N-acetylaspartic acid impairs enzymatic antioxidant defenses and enhances hydrogen peroxide concentration in rat brain. Metabolic Brain Disease, v. 25, p. 251-259, 2010.
27. Pederzolli, Carolina Didonet ; Mescka, Caroline Paula ; Zandoná, Bernardo Remuzzi ; Moura Coelho, Daniella ; Sgaravatti, Ângela Malysz ; SGARBI, Mirian Bonaldi ; Souza Wyse, Angela Terezinha ; Duval Wannmacher, Clóvis Milton ; Wajner, Moacir ; VARGAS, Carmen Regla ; Dutra-Filho, Carlos Severo . Acute administration of 5-oxoproline induces oxidative damage to lipids and proteins and impairs antioxidant defenses in cerebral cortex and cerebellum of young rats. Metabolic Brain Disease, v. 25, p. 145-154, 2010.
28. SCHUCK, Patrícia Fernanda ; FERREIRA, Gustavo da Costa ; Tahara, Erich Birelli ; Klamt, Fábio ; Kowaltowski, Alicia Juliana ; Wajner, Moacir . cis-4-decenoic acid provokes mitochondrial bioenergetic dysfunction in rat brain. Life Sciences (1973), v. 87, p. 139-146, 2010.
29. Pérez, Belén ; Angaroni, Celia ; Sánchez-Alcudia, Rocio ; Merinero, Begoña ; Pérez-Cerdá, Celia ; Specola, N. ; Rodríguez-Pombo, P. ; Wajner, Moacir ; Kremer, Raquel Dodelson ; Cornejo, Verónica ; Desviat, Lourdes R. ; Ugarte, Magdalena . The molecular landscape of propionic acidemia and methylmalonic aciduria in Latin America. Journal of Inherited Metabolic Disease, v. 33, p. 307-314, 2010.
30. LEIPNITZ, Guilhian ; Amaral, Alexandre U. ; Zanatta, Ângela ; SEMINOTTI, Bianca ; Fernandes, Carolina G. ; Knebel, Lisiane A. ; Vargas, Carmen R. ; Wajner, Moacir . Neurochemical evidence that phytanic acid induces oxidative damage and reduces the antioxidant defenses in cerebellum and cerebral cortex of rats. Life Sciences (1973), v. 87, p. 275-280, 2010.
31. Busanello, Estela Natacha Brandt ; VIEGAS, Carolina Maso ; Moura, Alana Pimentel ; Tonin, Anelise Miotti ; Grings, Mateus ; Vargas, Carmen R. ; Wajner, Moacir . In vitro evidence that phytanic acid compromises Na+,K+-ATPase activity and the electron flow through the respiratory chain in brain cortex from young rats. Brain Research, v. 1352, p. 231-238, 2010.
32. Ribas, Graziela S. ; Manfredini, Vanusa ; de Marco, Maria Gilda ; Vieira, Rosana B. ; Wayhs, Carlos Y. ; Vanzin, Camila S. ; Biancini, Giovana B. ; Wajner, Moacir ; Vargas, Carmen R. . Prevention by l-carnitine of DNA damage induced by propionic and l-methylmalonic acids in human peripheral leukocytes in vitro. Mutation Research. Genetic Toxicology and Environmental Mutagenesis, v. 702, p. 123-128, 2010.
33. LEIPNITZ, Guilhian ; SEMINOTTI, Bianca ; Amaral, Alexandre U. ; Fernandes, Carolina G. ; Dutra-Filho, Carlos S. ; Wajner, Moacir . Evidence that 2-methylacetoacetate induces oxidative stress in rat brain. Metabolic Brain Disease, v. 25, p. 261-267, 2010.
34. SEMINOTTI, B ; FERNANDES, C. G. ; LEPNITZ, G. ; AMARAL, A. U. ; ZANATTA, A. ; WAJNER, M. . Neurochemical evidence that lysine inhibits synaptic Na+K+-ATPase activity and provokes oxidative damage in striatum of young rats. Neuroscience Research, v. 36, p. 205-214, 2010.
35. SITTA, Â. ; BARCHAK, Alethéa ; DEON, Marion ; MARI, Jurema de ; BARDEN, Amanda T ; VANZIN, C.S. ; WAJNER, M. ; VARGAS, C. R. . L-carnitine blood levels and oxidative stress in treated phenylketonuric patients. Cellular and Molecular Neurobiology, v. 29, p. 211-218, 2010.
36. SITTA, Angela ; Barschak, Alethéa G. ; DEON, Marion ; Mari, Jurema F. ; Barden, Amanda T. ; Vanzin, Camila S. ; Biancini, Giovana B. ; Schwartz, Ida V. D. ; Wajner, Moacir ; Vargas, Carmen R. . l-Carnitine Blood Levels and Oxidative Stress in Treated Phenylketonuric Patients. Cellular and Molecular Neurobiology, v. 29, p. 211-218, 2009.
37. LEIPNITZ, Guilhian ; Solano, Alexandre F. ; SEMINOTTI, Bianca ; Amaral, Alexandre U. ; Fernandes, Carolina G. ; Beskow, Ana Paula ; Dutra Filho, Carlos S. ; Wajner, Moacir . Glycine Provokes Lipid Oxidative Damage and Reduces the Antioxidant Defenses in Brain Cortex of Young Rats. Cellular and Molecular Neurobiology, v. 29, p. 253-261, 2009.
38. SCHUCK, P ; FERREIRA, G ; VIEGAS, C ; TONIN, A ; BUSANELLO, E ; PETTENUZZO, L ; NETTO, C ; WAJNER, M ; WAJNER, M. . Chronic early postnatal administration of ethylmalonic acid to rats causes behavioral deficit. Behavioural Brain Research, v. 197, p. 364-370, 2009.
39. Santos, Eliseu Felippe ; Busanello, Estela Natacha Brandt ; Miglioranza, Anelise ; Zanatta, Ângela ; Barchak, Alethea Gatto ; VARGAS, Carmen Regla ; Saute, Jonas ; Rosa, Charles ; Carrion, Maria Júlia ; Camargo, Daiane ; Dalbem, André ; Costa, Jaderson Costa ; Sousa Miguel, Sandro René Pinto ; Mello Rieder, Carlos Roberto ; Wajner, Moacir . Evidence that folic acid deficiency is a major determinant of hyperhomocysteinemia in Parkinson´s disease. Metabolic Brain Disease, v. 24, p. 257-269, 2009.
40. WAJNER, M. ; COELHO, Daniella de Moura ; Ingrassia,Rafaela ; OLIVEIRA, A. B. ; Estela N. B. Busanello ; RAYMOND, K. ; PIRES, Ricardo ; Souza, Carolina F. ; GIUGLIANI, Roberto ; VARGAS, Carmen Regla . Selective Screening for organic acidemias by urine organic acid GC-MS analysis in Brazil: Fifteen-year experience. Clinica Chimica Acta, v. 400, p. 77-81, 2009.
41. Tonin, Anelise Miotti ; Ferreira, Gustavo Costa ; SCHUCK, Patrícia Fernanda ; VIEGAS, Carolina Maso ; Zanatta, Ângela ; LEIPNITZ, Guilhian ; SEMINOTTI, Bianca ; Milton Duvall Wannmacher, Clóvis ; Wajner, Moacir . Inhibition of creatine kinase activity by lysine in rat cerebral cortex. Metabolic Brain Disease, v. 24, p. 349-360, 2009.
42. Pederzolli, Carolina Didonet ; Rockenbach, Francieli Juliana ; Zanin, Fernanda Rech ; Henn, Nicoli Taiana ; Romagna, Eline Coan ; Sgaravatti, Ângela M. ; Wyse, Angela T. S. ; Wannmacher, Clóvis M. D. ; Wajner, Moacir ; Mattos Dutra, Ângela ; Dutra-Filho, Carlos S. . Intracerebroventricular administration of N-acetylaspartic acid impairs antioxidant defenses and promotes protein oxidation in cerebral cortex of rats. Metabolic Brain Disease, v. 24, p. 283-298, 2009.
43. da Silva, Lucila de Bortoli ; LEIPNITZ, Guilhian ; SEMINOTTI, Bianca ; Fernandes, Carolina G. ; Beskow, Ana Paula ; Amaral, Alexandre U. ; Wajner, Moacir . D-Serine induces lipid and protein oxidative damage and decreases glutathione levels in brain cortex of rats. Brain Research, v. 1256, p. 34-42, 2009.
44. Barschak, Alethéa G. ; SITTA, Angela ; DEON, Marion ; Busanello, Estela N.B. ; Coelho, Daniella M. ; CIPRIANI, Franciele ; Dutra-Filho, Carlos S. ; GIUGLIANI, Roberto ; Wajner, Moacir ; Vargas, Carmen R. . Amino acids levels and lipid peroxidation in maple syrup urine disease patients. Clinical Biochemistry, v. 42, p. 462-466, 2009.
45. Sgaravatti, Ângela M. ; Magnusson, Alessandra S. ; Oliveira, Amanda S. ; Mescka, Caroline P. ; Zanin, Fernanda ; Sgarbi, Mirian B. ; Pederzolli, Carolina D. ; Wyse, Angela T. S. ; Wannmacher, Clóvis M. D. ; Wajner, Moacir ; Dutra-Filho, Carlos S. . Effects of 1,4-butanediol administration on oxidative stress in rat brain: Study of the neurotoxicity of ?-hydroxybutyric acid in vivo. Metabolic Brain Disease, v. 24, p. 271-282, 2009.
46. SITTA, Angela ; Barschak, Alethéa G. ; DEON, Marion ; Barden, Amanda T. ; Biancini, Giovana B. ; Vargas, Paula R. ; de Souza, Carolina F. ; Netto, Cristina ; Wajner, Moacir ; Vargas, Carmen R. . Effect of short- and long-term exposition to high phenylalanine blood levels on oxidative damage in phenylketonuric patients. International Journal of Developmental Neuroscience, v. 27, p. 243-247, 2009.
47. Schuck, Patrícia F. ; Ferreira, Gustavo C. ; Moura, Alana P. ; Busanello, Estela N.B. ; Tonin, Anelise M. ; Dutra-Filho, Carlos S. ; Wajner, Moacir . Medium-chain fatty acids accumulating in MCAD deficiency elicit lipid and protein oxidative damage and decrease non-enzymatic antioxidant defenses in rat brain. Neurochemistry International, v. 54, p. 519-525, 2009.
48. STEENWEG, M. E. ; SALOMONS, G. S. ; YAPICI, Z. ; UZIEL, G. ; SCALAIS, E. ; ZAFEIRIOU, D. I. ; RUIZ-FALCO, M. L. ; MEJASKI-BOSNJAK, V. ; AUGOUSTIDES-SAVVAPOULOU, P. ; WAJNER, M. ; WALTER, J. ; BARTOLOME, M. T. A. ; AERSSENS, P. ; BARIC, I. ; BAUMANN, M. ; BONAFE, L. ; CHABROL, B. ; COKER, M. ; COOPER, S. ; FALIK-ZACCAI, T. ; GORMAN, M. ; HAHN, A. ; KING, M. ; KLERK, H. B. C. ; KORMAN, S. H. ; LEE, C. ; LUND, A. M. ; PASCUAL-CASTROVIEJO, I. ; ROOTWELT, T. ; ROUBERTIE, A. ; SCHIMMEL, U. ; SEIJO-MARTINEZ, M. ; SYKUT-CEGIELSKA, J. ; TREFZ, F. K. ; VLAHO, S. ; VODOPIUTZ, J. ; WALTER-DERBORT, C. ; SPREEUWENBERG, M. D. ; VERHOEVEN, N. M. ; STRUYS, E. A. ; JAKOBS, C. ; KNAAP, M. V. D. . L-2-Hydroxyglutaric Aciduria: Pattern of MR Imaging Abnormalities and Evolution in 55 Patients. Radiology, v. 251, p. 856-865, 2009.
49. VIEGAS, Carolina M ; ZANATTA, A. ; KNEBEL, L. A. ; SCHUCK, P. ; TONIN, Anelise ; FERREIRA, Gustavo C ; AMARAL, Alexandre ; DUTRA-FILHO, C. S. ; WANNMACHER, Clovis M.d. ; WAJNER, M. . Experimental evidence that ornithine and homocitrulline disrupt energy metabolism in brain of young rats. Brain Research, v. 1291, p. 102-112, 2009.
50. SITTA, Angela ; Manfredini, Vanusa ; Biasi, Lidiana ; Treméa, Roberta ; Schwartz, Ida V.D. ; Wajner, Moacir ; Vargas, Carmen R. . Evidence that DNA damage is associated to phenylalanine blood levels in leukocytes from phenylketonuric patients. Mutation Research. Genetic Toxicology and Environmental Mutagenesis, v. 679, p. 13-16, 2009.
51. Amaral, Alexandre Umpierrez ; LEIPNITZ, Guilhian ; Fernandes, Carolina Gonçalves ; SEMINOTTI, Bianca ; Zanatta, Ângela ; VIEGAS, Carolina Maso ; Dutra-Filho, Carlos Severo ; Wajner, Moacir . Evidence that the major metabolites accumulating in hyperornithinemia hyperammonemia homocitrullinuria syndrome induce oxidative stress in brain of young rats. International Journal of Developmental Neuroscience, v. 27, p. 635-641, 2009.
52. SCHUCK, P. ; BUSANELLO, E. N. B. ; MOURA, A P ; TONIN, Anelise ; GRINGS, M. ; RITTER, L. ; VARGAS, C. R. ; FERREIRA, G C ; WAJNER, M. . Promotion of lipid and protein oxidative damage in rat brain by ethylmalonic acid. Neurochemical Research, v. 35, p. 298-305, 2009.
53. SCHUCK, Patrícia Fernanda ; da Costa Ferreira, Gustavo ; Tonin, Anelise Miotti ; VIEGAS, Carolina Maso ; Busanello, Estela Natacha Brandt ; Moura, Alana Pimentel ; Zanatta, Ângela ; Klamt, Fábio ; Wajner, Moacir . Evidence that the major metabolites accumulating in medium-chain acyl-CoA dehydrogenase deficiency disturb mitochondrial energy homeostasis in rat brain. Brain Research, v. 1296, p. 117-126, 2009.
54. Zanatta, Ângela ; SCHUCK, Patrícia Fernanda ; VIEGAS, Carolina Maso ; Knebel, Lisiane Aurélio ; Busanello, Estela Natacha Brandt ; Moura, Alana Pimentel ; Wajner, Moacir . In vitro evidence that d-serine disturbs the citric acid cycle through inhibition of citrate synthase activity in rat cerebral cortex. Brain Research, v. 1298, p. 186-193, 2009.
55. Sgaravatti, Ângela M. ; Magnusson, Alessandra S. ; Oliveira, Amanda S. ; Rosa, Andréa P. ; Mescka, Caroline Paula ; Zanin, Fernanda R. ; Pederzolli, Carolina D. ; Wyse, Angela T. S. ; Wannmacher, Clóvis M. D. ; Wajner, Moacir ; Dutra-Filho, Carlos Severo . Tyrosine administration decreases glutathione and stimulates lipid and protein oxidation in rat cerebral cortex. Metabolic Brain Disease, v. 24, p. 415-425, 2009.
56. LEIPNITZ, Guilhian ; SEMINOTTI, Bianca ; Fernandes, Carolina G. ; Amaral, Alexandre U. ; Beskow, Ana Paula ; da Silva, Lucila de B. ; Zanatta, Ângela ; Ribeiro, César A.J. ; Vargas, Carmen R. ; Wajner, Moacir . Striatum is more vulnerable to oxidative damage induced by the metabolites accumulating in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency as compared to liver. International Journal of Developmental Neuroscience, v. 27, p. 351-356, 2009.
57. Ribeiro, César Augusto João ; LEIPNITZ, Guilhian ; Amaral, Alexandre Umpierrez ; de Bortoli, Giorgia ; SEMINOTTI, Bianca ; Wajner, Moacir . Creatine administration prevents Na+,K+-ATPase inhibition induced by intracerebroventricular administration of isovaleric acid in cerebral cortex of young rats. Brain Research, v. 1262, p. 81-88, 2009.
58. DEON, Marion ; SITTA, Angela A ; BARSCHACK, A. ; COELHO, Daniela Moura ; TERROSO, Thatiana ; SCHMITT, Graziela O ; Hector Y. C. Wanderley ; JARDIM, L. B. ; GIUGLIANI, Roberto ; WAJNER, M. ; VARGAS, Carmen Regla . Oxidative stress is induced in female carriers of X-linked adrenoleukodystrophy. Journal of the Neurological Sciences, v. 15, p. 79-83, 2008.
59. BARSCHAK, Alethéa Gatto ; SITTA, Angella ; DEON, Marion ; BARDEN, Amanda T ; DUTRAFILHO, Carlos Severo ; WAJNER, M. ; VARGAS, Carmen Regla . Oxidative stress in plasma from maple syrup urine disease patients during treatment. Metabolic Brain Disease, v. 23, p. 71-80, 2008.
60. RIBEIRO, C. A. J. ; SGARAVATTI, Angela M ; B, Rosa R ; SCHUCK, Patrícia Fernanda ; GRANDO, Vanessa ; SCHMIDT, Anna Laura ; FERREIRA, Gustavo da Costa ; PERRY, Marcos Luiz Santos ; DUTRAFILHO, Carlos Severo ; WAJNER, M. . Inhibition of brain energy metabolism by the branched-chain amino acids accumulating in maple syrup urine disease. Neurochemical Research, v. 33, p. 114-124, 2008.
61. LEIPNITZ, Guilhian ; SEMINOTTI, Bianca ; HAUBRICH, Josué ; DALCIN, Manuela Borges ; DALCIN, Karina Borges ; SOLANO, Alexandre F ; Geogia Bortoli ; B, Rosa R ; AMARAL, Alexandre ; DUTRAFILHO, Carlos Severo ; LATINI, Alexandra Susana ; WAJNER, M. . Evidence that 3-hydroxy-3-methylglutaric acid promotes lipid and protein oxidative damage and reduces the nonenzymatic antioxidant defenses in rat cerebral cortex. Journal of Neuroscience Research, v. 86, p. 683-693, 2008.
62. KESSLER, A. ; BIASIBETTI, M. ; FEKSA, Luciane Rosa ; RECH, Virginia Cielo ; D. A. da Silva Melo ; WAJNER, M. ; DUTRAFILHO, Carlos Severo ; WYSE, Angela Terezinha de Souza ; WANNMACHER, Clóvis Milton Duval . Effects of cysteamine on oxidative status in cerebral cortex of rats. Metabolic Brain Disease, v. 23, p. 81-93, 2008.
63. FERREIRA, Gustavo da Costa ; SCHUCK, Patrícia Fernanda ; VIEGAS, Carolina M ; TONIN, Anelise ; RIBEIRO, C. A. J. ; PETTENUZZO, Letícia Ferreira ; Lenir O. Pereira ; A NETTO, C ; WAJNER, M. . Chronic early postnatal glutaric acid administration causes cognitive deficits in the water maze. Behavioural Brain Research, v. 187, p. 411-416, 2008.
64. Sandra R. Mirandola ; Daniela R. Melo ; SCHUCK, Patricia Fernanda ; FERREIRA, Gustavo da C ; WAJNER, M. ; CASTILHO, Roger F . Methylmalonate inhibits succinate-suported oxygen consumption by interfering with mitochondrial succinate uptake. Journal of Inherited Metabolic Disease, v. 31, p. 44-54, 2008.
65. VARGAS, C. R. ; SITTA, Angela ; SCHMITT, Graziela O ; FERREIRA, Gustavo da Costa ; M. L. Cardoso ; COELHO, Daniella ; GIBSON, K. M. ; WAJNER, M. . Incidence of 3-hydroxy-3-methylglutaril-coenzyme A lyase (HL) deficiency in Brazil, South America. Journal of Inherited Metabolic Disease, v. 31, p. 127-130, 2008.
66. DEON, Marion ; GARCIA, Mariana ; SITTA, Angela A ; BARSCHAK, Alethéa Gatto ; COELHO, Daniela Moura ; SCHIMIT, Graziela ; PIGATTO, Maiara Cássia ; JARDIM, Laura ; WAJNER, M. ; GIUGLIANI, Roberto ; VARGAS, Carmen Regla . Hexacosanoic and docosanoic acids plasma levels in patients with cerebral childhood and asymptomatic X-linked adrenoleukodystrophy: Lorenzo's oil effect. Metabolic Brain Disease, v. 23, p. 43-49, 2008.
67. KESSLER, A. ; BIASIBETTI, M. ; D. A. da Silva Melo ; WAJNER, M. ; DUTRA-FILHO, C S ; WYSE, Angela Terezinha de Souza ; WANNMACHER, Clovis M D . Antioxidant effect of cysteamine in brain cortex of young rats. Neurochemical Research, v. 33, p. 737-744, 2008.
68. VIEGAS, Carolina Maso ; FERREIRA, Gustavo da Costa ; SCHUCK, Patrícia Fernanda ; TONIN, Anelise ; Angela Zanatta ; WYSE, Angela Terezinha de Souza ; DUTRA-FILHO, C. S. ; WANNMACHER, Clóvis Milton Duval ; WAJNER, M. . Evidence that 3-hydroxyisobutyric acid inhibits key enzymes of energy metabolism in cerebral cortex of young rats. International Journal of Developmental Neuroscience, v. 26, p. 293-299, 2008.
69. FEKSA, Luciane Rosa ; LATINI, Alexandra Susana ; RECH, Virginia Cielo ; Patrícia Feksa ; KOCH, Gustavo W ; AMARAL, Maria Fernanda A Do ; LEIPNITZ, Guilhian ; DUTRA-FILHO, C. S. ; WAJNER, M. ; WANNMACHER, Clóvis Milton Duval . Tryptophan administration induces oxidative stress in brain cortex of rats. Metabolic Brain Disease, v. 23, p. 221-233, 2008.
70. A, Solano ; LEIPNITZ, Guilhian ; de BORTOLI, G. M. ; SEMINOTTI, Bianca ; AMARAL, Alexandre ; FERNANDES, C. G. ; LATINI, A ; LATINI, Alexandfa ; LATINI, Alexandra ; DUTRA-FILHO, C. S. ; WAJNER, M. . Induction of oxidative stress by the metabolites accumulating on isovaleric acimedia in brain cortex of young rats. Free Radical Research, v. 42, p. 707-715, 2008.
71. SEMINOTTI, B ; LEIPNITZ, G ; AMARAL, A U ; FERNANDES, C. G. ; SILVA, L. B. ; TONIN, A ; VARGAS, C. R. ; WAJNER, M . Lysine induces lipid and protein damage and decreases reduced glutathione concentrations in brain of young rats. International Journal of Developmental Neuroscience, v. 26, p. 693-698, 2008.
72. Zugno, Alexandra I. ; STEFANELLO, Francieli M. ; Scherer, Emilene B. S. ; MATTOS, Cristiane ; Pederzolli, Carolina D. ; Andrade, Vanessa M. ; Wannmacher, Clovis M. D. ; WAJNER, M. ; Dutra-Filho, Carlos S. ; Wyse, Angela T. S. . Guanidinoacetate Decreases Antioxidant Defenses and Total Protein Sulfhydryl Content in Striatum of Rats. Neurochemical Research, v. 33, p. 1804-1810, 2008.
73. SGARAVATTI, A ; VARGAS, B ; ZANDONA, B ; DECKMANN, K ; ROCKENBACH, F ; MORAES, T ; MONSERRAT, J ; SGARBI, M ; PEDERZOLLI, C ; WYSE, A ; WANNMACHER, Clóvis M ; WAJNER, M. ; DUTRAFILHO, Carlos Severo . Tyrosine promotes oxidative stress in cerebral cortex of young rats. International Journal of Developmental Neuroscience, v. 26, p. 551-559, 2008.
74. BESKOW, A. P. ; FERNANDES, C. G. ; LEPNITZ, G. ; SILVA, L. B. ; SEMINOTTI, Bianca ; AMARAL, Alexandre ; WYSE, Ângela ; WANNMACHER, C. M. D. ; WANNMACHER, C. M. D. ; DUTRA FILHO, Carlos Severo ; WAJNER, M. . Influence of ketone bodies on oxidative stress parameters in brain of developing rats in vitro.. Metabolic Brain Disease, v. 23, p. 411-425, 2008.
75. Oliveira S ; FERNANDEZ, A. ; LATINI, Alexandra ; Juan Carlos Rosillo ; Casanova G ; WAJNER, M. ; Cassina P ; Barbeito L . Astrocytic proliferation and mithocondrial dysfunction induced by accumulated glutaric acidemia I (GAI) metabolites: possible implications for GAI pathogenesis. Neurobiology of Disease, v. 32, p. 528-534, 2008.
76. LEIPNITZ, Guilhian ; SEMINOTTI, Bianca ; Amaral, Alexandre U. ; de Bortoli, Giorgia ; SOLANO, Alexandre ; Schuck, Patrícia F. ; Wyse, Ângela T.S. ; Wannmacher, Clóvis M.D. ; LATINI, Alexandra ; Wajner, Moacir . Induction of oxidative stress by the metabolites accumulating in 3-methylglutaconic aciduria in cerebral cortex of young rats. Life Sciences, v. 82, p. 652-662, 2008.
77. BARSCHAK, A ; MARCHESAN, C ; SITTA, A ; DEON, M ; GIUGLIANI, R ; WAJNER, M ; VARGAS, C . Maple syrup urine disease in treated patients: Biochemical and oxidative stress profiles. Clinical Biochemistry, v. 41, p. 317-324, 2008.
78. DELWING, Débora ; CORNELIO, Andrea R ; WAJNER, M. ; WANNMACHER, Clóvis Md ; WYSE, Angela T S . Arginine administration reduces creatine kinase activity in rat cerebellum. Metabolic Brain Disease, v. 22, n. 1, p. 13-23, 2007.
79. STEFANELLO, Francieli M ; MATTÉ, Cristine ; SCHERER, Emilene B ; WANNMACHER, Clóvis Md ; WAJNER, M. ; WYSE, Angela Ts . Chemically-induced model of hypermethioninemia in rats. Journal of Neuroscience Methods, v. 160, n. 1, p. 1-4, 2007.
80. LEIPNITZ, Guilhian ; SCHUMACHER, Cristiana ; DALCIN, Karina B ; SCUSSIATO, Karina ; SOLANO, Alexandre ; FUNCHAL, Cláudia ; DUTRA FILHO, Carlos S ; WYSE, Angela Ts ; WANNMACHER, Clóvis Md ; LATINI, Alexandra ; WAJNER, M. . In vitro evidence for an antioxidant role of 3-hydroxykynurenine and 3-hydroxyanhranilic acid inthe brain. Neurochemistry International, v. 50, n. 1, p. 83-94, 2007.
81. SCHUCK, Patrícia F ; TONIN, Anelise ; FERREIRA, Gustavo C ; VIEGAS, Carolina M ; LATINI, Alexandra ; WANNMACHER, Clóvis Md ; WYSE, Angela Ts ; DUTRA FILHO, Carlos S ; WAJNER, M. . Kynurenines impair energy metabolism in rat cerebral cortex. Cellular and Molecular Biology (Print) (Cessou em 2004), v. 27, n. 1, p. 147-160, 2007.
82. PEDERZOLLI, Carolina D ; SGARAVATTI, Angela M ; BRAUM, César A ; PRESTES, Cristina C ; ZORZI, Giovanni K ; SGARBI, Mirian B ; WYSE, Angela Ts ; WANNMACHER, Clóvis Md ; WAJNER, M. ; DUTRAFILHO, Carlos S . 5-oxoproline reduces non-enzymatic antioxidant defenses invitro in rat brain. Metabolic Brain Disease, v. 22, n. 1, p. 51-65, 2007.
83. SCHUCK, Patricia F ; TONIN, Anelise ; FERREIRA, Gustavo da Costa ; ROSA, Rafael Borba ; LATINI, Alexandra ; BALESTRO, Fabrício ; PERRY, Marcos Luiz Santos ; WANNMACHER, Clóvis Milton Duval ; WYSE, Angela Ts ; WAJNER, M. . IN VITRO EFFECT OF QUINOLINIC ACID ON ENERGY METABOLISM IN BRAIN OF YOUNG RATS. Neuroscience Research, v. 57, n. 2, p. 277-288, 2007.
84. SGARAVATTI, Angela M ; SGARBI, Mirian B ; TESTA, Carla G ; DURIGON, Karina ; PEDERZOLLI, Carolina D ; PRESTES, Cristina C ; WYSE, Angela Ts ; WANNMACHER, Clóvis Md ; WAJNER, M. ; DUTRAFILHO, Carlos S . Gama-hydroxybutyric acid induces oxidative stress incerebralcortex of young rats. Neurochemistry International, v. 50, n. 3, p. 564-570, 2007.
85. LATINI, Alexandra ; FERREIRA, Gustavo C ; SCUSSIATO, Karina ; SCHUCK, Patrícia F ; SOLANO, Alexandre F ; DUTRAFILHO, Carlos S ; VARGAS, Carmen R ; WAJNER, M. . Induction of oxidative stess by chronic and acute glutaric acid administration to rats. Cellular and Molecular Neurobiology, v. 27, p. 423-438, 2007.
86. FERREIRA, Gustavo ; SCHUCK, Patrícia F ; VIEGAS, Carolina ; TONIN, Anelise ; LATINI, Alexandra ; DUTRAFILHO, Carlos S ; WANNMACHER, Angela Ts Wyseclóvis Md ; WAJNER, M. . Energy metabolism is compromised in skeletal muscle of rats chronically-treated with glutaric acid. Metabolic Brain Disease, v. 22, n. 1, p. 111-123, 2007.
87. ZUGNO, Alexandra I ; SCHERER, Emilene Bs ; MATTOS, Cristiane ; RIBEIRO, C. A. J. ; WANNMACHER, Clóvis M D ; WAJNER, M. ; WYSE, Angela Ts . Evidence that the inhibitory effects of guanidinoacetate on the activities of the respiratory chain, Na+K+ ATPase and creatine kinase can be differentially prevented by taurine and vitamins E and C administration in rat striatum in vivo. Biochimica et Biophysica Acta. Molecular Basis of Disease, v. 1772, n. 5, p. 563-569, 2007.
88. DELWING, Debora ; STEFANELLO, Francieli M ; WAJNER, M. ; PERRY, Marcos L ; WYSE, Angela . Inhibition of CO2 production from glucose by arginine in brain slices of rats. Metabolic Brain Disease, 2007.
89. BARSCHAK, Alethea G ; SITTA, Angela ; DEON, Marion ; BARDEN, Amanda T ; SCHMITT, Graziela O ; DUTRAFILHO, Carlos S ; WAJNER, M. ; VARGAS, Carmen R . Erythrocyte glutathione peroxidase activity and plasma selenium concentration are reduced in maple syrup urine disease patients during treatment. International Journal of Developmental Neuroscience, v. 25, p. 335-338, 2007.
90. PESSOAPUREUR, Regina ; WAJNER, M. . CYTOSKELETON AS A POTENTIAL TARGET IN THE NEUROPATHOLOGY OF MAPLE SYRUP URINE DISEASE: INSIGHT FROM ANIMAL STUDIES. Journal of Inherited Metabolic Disease, 2007.
91. LATINI, Alexandra Susana ; SCUSSIATO, Karina ; LEIPNITZ, Guilhian ; GIBSON, K. M. ; WAJNER, M. . Evidence for oxidative stress in tissues derived from succinate semialdehyde dehydrogenase deficient mice. Journal of Inherited Metabolic Disease, v. 30, p. 800-810, 2007.
92. PEDERZOLLI, Carolina Dinonet ; MESCKA, Caroline P ; SCAPIN, Fernanda ; F. J. Rockenbach ; SGARAVATTI, Angela Malysz ; SGARBI, Mirian Bonaldi ; WYSE, Â. T. S. ; WANNMACHER, Clóvis Milton Duval ; WAJNER, M. ; DUTRAFILHO, Carlos Severo . N-acetylaspartic acid promotes oxidative stress in cerebral cortex of rats. International Journal of Developmental Neuroscience, v. 25, p. 317-324, 2007.
93. RECH, Virginia Cielo ; FEKSA, Luciane Rosa ; Arevalo do Amaral MF ; KOCH, Gustavo W ; WAJNER, M. ; DUTRAFILHO, Carlos Severo ; WYSE, Â. T. S. ; WANNMACHER, Clóvis Milton Duval . Promotion of oxidative stress in kidney of rats loaded with cystine dimethyl ester. Pediatric Nephrology (Berlin, West), v. 22, p. 1121-1128, 2007.
94. RIBEIRO, C. A. J. ; BALESTRO, Fabrício ; GRANDO, Vanessa ; WAJNER, M. . Isovaleric acid reduces Na+, K+-ATPase activity in synaptic membranes from cerebral cortex of young rats. Cellular and Molecular Neurobiology, v. 27, p. 529-540, 2007.
95. PELAEZ, Priscilla de Lima ; FUNCHAL, Cláudia da Silva ; LOUREIRO, Samata Oliveira ; HEIMFARTH, Luana ; ZAMONER, Ariane ; GOTTFRIED, Carmen ; LATINI, Alexandra ; WAJNER, M. ; PESSOAPUREUR, Regina . Branched-chain amino acids accumulating in maple syrup urine disease induce morphological alterations in C6 glioma cells probably through reactive species. International Journal of Developmental Neuroscience, v. 25, p. 181-189, 2007.
96. WAJNER, André ; BüRGER, C. ; DUTRAFILHO, Carlos Severo ; WAJNER, M. ; WYSE, Angela Terezinha Souza ; WANNMACHER, Clóvis Milton Durval . Synaptic plasma membrane Na(+), K (+)-ATPase activity is significantly reduced by the alpha-keto acids accumulating in maple syrup urine disease in rat cerebral cortex. Metabolic Brain Disease, v. 22, p. 77-88, 2007.
97. ZUGNO, Alexandra I ; OLIVEIRA, Diogo L de ; SCHERER, Emilene Bs ; WAJNER, M. ; WOFCHUK, S. T. ; WYSE, Angela Terezinha Do Souza . Guanidinoacetate inhibits glutamate uptake in rat striatum of rats at different ages. Neurochemical Research, v. 32, p. 959-964, 2007.
98. FUNCHAL, Claudia ; TRAMONTINA, Francine ; SANTOS, Ana Quincozes dos ; Fraga de Souza D ; GONÇALVES, Carlos A ; PESSOAPUREUR, Regina ; WAJNER, M. . Effect of the branched-chain alpha-keto acids accumulating in maple syrup urine disease on S100B release from glial cells. Journal of the Neurological Sciences, v. 260, p. 87-94, 2007.
99. SCHUCK, Patrícia Fernanda ; CEOLATO, Paula Casagrande ; FERREIRA, Gustavo da Costa ; TONIN, Anelise ; LEIPNITZ, Guilhian ; DUTRAFILHO, Carlos Severo ; LATINI, Alexandra Susana ; WAJNER, M. . Oxidative stress induction by cis-4-decenoic acid: Relevance for MCAD deficiency. Free Radical Research, v. 41, p. 1261-1272, 2007.
100. DEON, Marion ; SITTA, Angella ; BARSCHACK, A. ; COELHO, Daniela Moura ; PIGATTO, Maiara Cássia ; SCHMITT, Graziela O ; JARDIM, L. B. ; GIUGLIANI, Roberto ; WAJNER, M. ; VARGAS, Carmen Regla . Induction of lipid peroxidation and decrease of antioxidant defenses in symptomatic and asymptomatic patients with X-linked adrenoleukodystrophy. International Journal of Developmental Neuroscience, v. 25, p. 441-444, 2007.
101. DALCIN, Karina Borges ; BORBA, Rafael Rosa ; SCHMIDT, Anna Laura ; WINTER, Juliana da Silva ; LEIPNITZ, Guilhian ; DUTRAFILHO, Carlos Severo ; WANNMACHER, Clóvis Milton Duval ; PORCIÚNCULA, Lisiane O ; SOUZA, Diogo Onofre ; WAJNER, M. . Age and brain structural related effects of glutaric and 3-hydroxyglutaric acids on glutamate binding to plasma membranes during rat brain development. Cellular and Molecular Neurobiology, v. 27, p. 805-818, 2007.
102. FERREIRA, Gustavo da Costa ; TONIN, Anelise ; SCHUCK, Patrícia Fernanda ; VIEGAS, Carolina Maso ; CEOLATO, Paula Casagrande ; LATINI, Alexandra Susana ; PERRY, Marcos Luiz Santos ; WYSE, Angela Terezinha de Souza ; DUTRAFILHO, Carlos Severo ; WANNMACHER, Clóvis Milton Duval ; VARGAS, Carmen Regla ; WAJNER, M. . Evidence for a synergistic action of glutaric and 3-hydroxyglutaric acids disturbing rat brain energy metabolism. International Journal of Developmental Neuroscience, v. 25, p. 391-398, 2007.
103. BORBA, Rafael Rosa ; DALCIN, Karina Borges ; SCHMIDT, Anna Laura ; Daniéli Gerhardt ; RIBEIRO, C. A. J. ; FERREIRA, Gustavo da Costa ; SCHUCK, Patrícia Fernanda ; WYSE, Angela Terezinha de Souza ; PORCIÚNCULA, Lisiane O ; WOFCHUCK, Suzana ; SALBEGO, C. G. ; SOUZA, Diogo Onofre de ; WAJNER, M. . Evidence that glutaric acid reduces glutamate uptake by cerebral cortex of infant rats. Life Sciences, v. 81, p. 1668-1676, 2007.
104. BARSCHAK, Alethea G ; FERREIRA, Gustavo da C ; ANDRÉ, Karina R ; SCHUCK, Patrícia F ; VIEGAS, Carolina M ; TONIN, Anelise ; DUTRA FILHO, Carlos S ; WYSE, Angela Ts ; WANNMACHER, Clóvis Md ; VARGAS, Carmen R ; WAJNER, M. . Inhibition of the electron transport chain and creatine kinase activity by ethylmalonic acid in human skeletal muscle. Metabolic Brain Disease, v. 21, n. 1, p. 11-19, 2006.
105. FERREIRA, Gustavo da C ; ANDRÉ, Karina R ; SCHUCK, Patrícia F ; VIEGAS, Carolina M ; TONIN, Anelise ; COELHO, Daniela ; WYSE, Angela Ts ; WANNMACHER, Clóvis Md ; VARGAS, Carmen ; WAJNER, M. . Effect of in vivo administration of ethylmalonic acid on energy metabolism in rat tissues. Metabolic Brain Disease, v. 21, n. 1, p. 29-39, 2006.
106. ASSIS, Denis Reis de ; MARIA, R C ; FERREIRA, Gustavo ; SHUCK, Patrícia ; LATINI, Alexandra ; DUTRAFILHO, Carlos Severo ; WANNMACHER, Clovis ; WAJNER, M. . Na+, K+-ATPase activity is markedly reduced by cis-4-decenoic acid in synaptic plasma membranes from cerebral cortex of rats. Experimental Neurology, v. 197, n. 1, p. 143-149, 2006.
107. SCHERER, Emilene B S ; SCHUCK, Patrícia F ; OLIVEIRA, Diogo L ; WOFCHUCK, Suzana ; WANNMACHER, Clóvis Md ; WAJNER, M. ; WYSE, Angela Ts . Intrastriatal administration of guanidinoacetate inhibits Na+,K+-ATPase and creatine kinase activities in rat striatum. Metabolic Brain Disease, v. 21, n. 1, p. 41-50, 2006.
108. FUNCHAL, Cláudia ; SCHUCK, Patrícia Fernanda ; SANTOS, André Quincozes dos ; JACQUESSILVA, Maria Carolina ; GOTTFRIED, Carmen ; PUREUR, Regina Pessoa ; WAJNER, M. . Creatine and antioxidant treatment prevent the inhibition of creatine kinase activity and the morphological alterations of C6 glioma cells induced by the branched-chain alpha-keto acids accumulating in maple syrup urine disease. Cellular and Molecular Neurobiology, v. 26, n. 1, p. 67-79, 2006.
109. PETTENUZZO, Letícia F ; FERREIRA, Gustavo da C ; SCHMIDT, Anna Laura ; DUTRA FILHO, Carlos S ; WYSE, Angela Ts ; WAJNER, M. . Differential inhibitory effects of methylmalonic acid on respiratory chain complex activities inr at tissues. International Journal of Developmental Neuroscience, v. 24, n. 1, p. 45-52, 2006.
110. DELWING, Débora ; TAGLIARI, Bárbara ; CHIARANI, Fábria ; WANNMACHER, Clovis M.d. ; WAJNER, M. ; WYSE, Angela Terezinha de Souza . ALPHA-TOCOPHEROL AND ASCORBIC ACID ADMINISTRATION PREVENTS THE IMPAIRMENT OF BRAIN ENERGY METABOLISM OF HYPERARGININEMIC RATS . Cellular and Molecular Neurobiology, v. 26, n. 2, p. 177-189, 2006.
111. MATÉ, Cristiane ; DURIGON, Eduardo ; STEFANELLO, Francieli M ; CIPRIANI, Franciele ; WAJNER, M. ; WYSE, Angela Ts . Folic acid pretreatment prevents the reduction of Na+,K+ ATPase and butyrylcholinesterase activities in rats subjected to acute hyperhomocysteinemia. International Journal of Developmental Neuroscience, v. 24, n. 1, p. 3-8, 2006.
112. FEKSA, Luciane R ; LATINI, Alexandra ; RECH, Virginia C ; WAJNER, M. ; DUTRA FILHO, Carlos S ; WYSE, Angela T S ; WANNMACHER, Clovis M D . Promotion of oxidative stres by L-tryptophan in cerebral cortex of rats. Neurochemistry International, v. 49, p. 87-93, 2006.
113. VASQUES, Vilson ; BRINCO, Fernando ; VIEGAS, Carolina M ; WAJNER, M. . Creatine prevents behavioral alterations caused by methylmalonic acid administration into the hippocampus of rats in the open field task. Journal of the Neurological Sciences, v. 244, n. 1-2, p. 23-29, 2006.
114. PRESTES, Cristina C ; SGARAVATTI, Angela M ; PEDERZOLLI, Carolina D ; SGARBI, Mirin B ; ZORZI, Giovanni K ; WANNMACHER, Clóvis Md ; WAJNER, M. ; WYSE, Angela T ; DUTRAFILHO, Carlos Severo . Citruline and ammonia accumulating in citrulinemia reduce the antioxidant capacity of rat brain in vitro. Metabolic Brain Disease, v. 21, n. 1, p. 63-74, 2006.
115. ALMEIDA, Lúcia M V de ; FUNCHAL, Cláudia ; GOTTFRIED, Carmen ; WAJNER, M. ; PUREUR, Regina Pessoa . Propionic acid induces cytoskeletal alterations in cultured astrocytes from rat cerebral cortex. Metabolic Brain Disease, v. 21, n. 1, p. 51-62, 2006.
116. BRIDI, Raquel ; FONTELLA, Fernanda U ; PULRONICK, Vânia ; BRAUN, César A ; ZORZI, Giovanni K ; COELHO, Daniella ; WAJNER, M. ; VARGAS, Carmen Regla ; DUTRA FILHO, Carlos Severo . A chemically-induced acute model of maple syrup urine disease in rats for neurochemical studies. Journal of Neuroscience Methods, v. 155, n. 2, p. 224-230, 2006.
117. KOLKER, Stefan ; GARBADE, Sven F ; GREENBERG, Cherry R ; LEONARD, Janes ; SAUDUBRAY, Jean Marie ; RIBES, Antonia ; KALKANOGLU, Serap ; LUND, Allan ; MERINERO, Begona ; WAJNER, M. ; HOFFMANN, Georg . Natural history, outcome, treatment eficacy in children and adults with glutaryl-CoA dehydrogenase deficiency. Pediatric Research, v. 59, n. 6, p. 840-847, 2006.
118. RECH, Virginia C ; ATHAYDES, Genaro A ; FEKSA, Luciane R ; DORNELLES, Paula K B ; R JUNIOR, Valnes ; DUTRA FILHO, Carlos S ; WYSE, Angela Ts ; WAJNER, M. ; WANNMACHER, Clóvis M . Inhibition of creatine kinase activity by cystine in the kidney of young rats. Pediatric Research, v. 60, n. 2, p. 190-195, 2006.
119. PINTO, L ; ZEN, P ; ROSA, R ; PASKULIN, G ; PERLA, A ; BAREA, L ; BAUMGARTNER, M R ; DANTAS, M F ; FOWLER, B ; GIUGLIANI, R ; VARGAS, Carmen R ; WAJNER, M. ; GRAZIADIO, C . Isolated 3-methylcrotonyl-coenzyme A carboxylase deficiency in a child with metabolic stroke. Journal of Inherited Metabolic Disease, v. 29, n. 1, p. 205-206, 2006.
120. BARSCHAK, Alethea G ; SITTA, Angella ; DEON, Marion ; OLIVEIRA, Marcella H de ; HAESER, Alexsandro ; DUTRA FILHO, Carlos S ; WAJNER, M. ; VARGAS, Carmen R . Evidence that oxidative stress is increased in plasma from patients with maple syrup urine disease. Metabolic Brain Disease, v. 21, n. 4, p. 279-286, 2006.
121. SITTA, Angela A ; TERROSO, T ; BARSCHAK, Alethea G ; DEON, M ; PIRES, Ricardo ; GIUGLIANI, Roberto ; DUTRA FILHO, Carlos S ; WAJNER, M. ; VARGAS, Carmen R . Investigation of oxidative stress parameters in treated phenylketonuric patients. Metabolic Brain Disease, v. 21, n. 4, p. 287-296, 2006.
122. DEON, Marion ; WAJNER, M. ; SARTORI, Lisana R ; FITARELLI, Douglas ; COELHO, Daniela M ; SITTA, Angela ; BARSCHAK, Alethea G ; FERREIRA, Gustavo C ; HAESER, Alexsandro ; GIUGLIANI, Roberto ; VARGAS, Carmen R . The effect of Lorenzo´s oil on oxidative stress in X-linked adrenoleukodystrophy. Journal of the Neurological Sciences, v. 247, n. 2, p. 157-164, 2006.
123. FUNCHAL, Cláudia ; LATINI, Alexandra ; JACQUESSILVA, Maria Caroline ; SANTOS, André Quincozes dos ; BUZIN, Luciane ; GOTTFRIED, Carmen ; WAJNER, M. ; PUREUR, Regina Pessoa . Branched-chain alpha-keto acids accumulating in maple syrup urine disease induce morphological alterations and oxidative stress in glial cells. Neurochemistry International, v. 20, p. 205-217, 2006.
124. RIBEIRO, C. A. J. ; GRANDO, Vanessa ; DUTRA FILHO, Carlos S ; WANNMACHER, Clóvis M D ; WAJNER, M. . EVIDENCE THAT QUINOLINIC ACID SEVERELY IMPAIRS ENERGY METABOLISM THROUGH ACTIVATION OF NMDA RECEPTORS IN STRIATUM FROM DEVELOPING RATS. Journal of Neurochemistry, v. 99, p. 1531-1542, 2006.
125. BAVARESCO, Caren Serra ; CHIARANI, Fabria ; WAJNER, M. ; ALEXANDRE NETTO, Carlos ; SOUZA, Angela Ts . Intrastriatal hypoxanthine administration affects Na+,K+-ATPase, acethylcholinestersase and catalase activities in striatum, hippocampus and cerebralcortex of rats. International Journal of Developmental Neuroscience, v. 24, n. 7, p. 411-417, 2006.
126. CORNELIO, Andrea R ; RODRIGUESJUNIOR, Valnes S ; RECH, Virginia Cielo ; WYSE, Angela Ts ; DUTRA FILHO, Carlos S ; WAJNER, M. ; WANNMACHER, Clóvis M D . Inhibition of creatine kinase activity from rat cerebral cortex by 3-hydroxykynurenine. Brain Research, v. 1124, n. 1, p. 188-196, 2006.
127. FUNCHAL, Cláudia ; LATINI, Alexandra ; JACQUESSILVA, Mc ; SANTOS, Aq dos ; BUZIN, L ; GOTTFRIED, Carmen ; WAJNER, M. ; PUREUR, R Pessoa . Morphological alterations and inductionof oxidative stress inglial cells caused by the branched-chain keto acids accumulating in maple syrup urine disease. Neurochemistry International, v. 49, n. 7, p. 640-650, 2006.
128. STEFANELLO, Francieli M. ; FRANZON, Renata ; TAGLIARI, Bárbara ; WANNMACHER, Clovis M.d. ; WAJNER, M. ; WYSE, Angela Ts . Reduction of butyrylcholinesterase activity in rat serum subjected to hyperhomocysteinemia. Metabolic Brain Disease, v. 20, n. 2, p. 97-103, 2005.
129. BRIDI, Raquel ; LATINI, Alexandra ; BRAUM, César A ; ZORZI, Giovanni K ; WAJNER, M. ; LISSI, Eduardo ; DUTRA FILHO, Carlos Severo . Evaluation of the mechanisms involved in leucine-induced oxidative damage in cerebral cortex of young rats. Free Radical Research, v. 39, n. 1, p. 71-79, 2005.
130. FLECK, Rochele M Muller ; RODRIGUES JUNIOR, Valnes ; GIACOMAZZI, Juliana ; PARISSOTO, Daiana ; DUTRA FILHO, Carlos Severo ; WYSE, Angela Terezinha de Souza ; WAJNER, M. ; WANNBMACHER, Clóvis Miltom Duval . Cysteamine prevents and reverses the inhibition of creatine kinase activity caused by cystine inrat braincortex. Neurochemistry International, v. 46, n. 5, p. 391-397, 2005.
131. LOUREIRO, Samata Oliveira ; PELAEZ, Priscilla de Lima ; HEIMFARTH, Luana ; SOUZA, Diogo Onofre ; WAJNER, M. ; PUREUR, Regina Pessoa . Propionic and methylmalonic acids increase cAMP levels in slices of cerebral cortex of young rats via adrenergic and glutamatergic mechanisms. Biochimica and Biophysica Acta, v. 1740, n. 3, p. 460-466, 2005.
132. ROSA, Rafael B ; SCHUCK, Patrícia F ; ASSIS, Denis R de ; DALCIN, Karina B ; RIBEIRO, C. A. J. ; FERREIRA, Gustavo C ; MARIA, R C ; LEIPNITZ, Guilhian ; PERRY, Marcos L ; DUTRAFILHO, Carlos S ; WYSE, Angela Ts ; WANNMACHER, Clóvis M D ; WAJNER, M. . Inhibition of energy metabolism by 2-methylacetoacetate and 2-methyl-3-hydroxybutyrate incerebral cortex of developing rats. Journal of Inherited Metabolic Disease, v. 28, n. 4, p. 501-515, 2005.
133. VASQUES, Vilsonde Castro ; BRINCO, Fabrício ; WAJNER, M. . Intrahippocampal administration of thebranched-chain alpha-hydroxy acids accumulating in maple syrup urine disease compromises rat performance in aversive and non-aversive behavioral tasks. Journal of the Neurological Sciences, v. 232, n. 1-2, p. 11-21, 2005.
134. DELWING, Daniela ; CHIARANI, Fábria ; BAVARESCO, Caren S ; WANNMACHER, Clóvis Md ; WAJNER, M. ; DUTRA FILHO, Carlos S ; WYSE, Angela T S . Protective effect of antioxidants on brain oxidative damage caused by proline administration. Neuroscience Research, v. 52, n. 1, p. 69-74, 2005.
135. DELWING, Daniela ; CHIARANI, Fábria ; WANNMACHER, Clóvis M D ; WAJNER, M. ; WYSE, Angela T S . Effect of hyperprolinemia onacethylcolinesterase and butyrylcholinesterase activities in rat. Amino Acids (Wien), v. 28, n. 3, p. 305-308, 2005.
136. SIRTORI, Lisana R ; DUTRAFILHO, Carlos Severo ; FITARELLI, Douglas ; SITTA, Angela ; HAESER, Alexandro ; BARSCHAK, Alethea G ; WAJNER, M. ; COELHO, Daniela ; LLESUY, Susana ; BELLÓKLEIN, Adriane ; GIUGLIANI, Roberto ; DEON, Marion ; VARGAS, Carmen R . Oxidative stress in patients with phenylketonuria. Biochimica and Biophysica Acta, v. 1740, n. 1, p. 68-73, 2005.
137. BRIDI, Raquel ; BRAUN, César A ; ZORZI, Giovanni K ; WANNMACHER, Clóvis Md ; WAJNER, M. ; LISSI, Eduardo G ; DUTRAFILHO, Carlos Severo . Alpha-keto acids accumulating in maple syrup urine disease stimulate lipid peroxidation and reduce antioxidant defences incerebral cortex from young rats. Metabolic Brain Disease, v. 20, n. 2, p. 155-167, 2005.
138. BAVARESCO, Caren Serra ; CHIARANI, Fabria ; MATTÉ, Cristiane ; WAJNER, M. ; ALEXANDRE NETTO, Carlos ; WYSE, Angela Terezinha de Souza . Effect of hypoxanthine on Na+,K+-ATPase activity and some parameters of oxidaive stress in rat striatum. Brain Research, v. 1041, n. 2, p. 198-204, 2005.
139. FUNCHAL, Cláudia ; GOTTFRIED, Carmen ; ANDRADE, Lúcia M F de ; SANTOS, André Quincozes dos ; WAJNER, M. ; PUREUR, Regina Pessoa . Morphological alterations and cell death provoked by the branched chain alpha-amino acids accumulating in maple syrup urine disease in astrocytes from rat cerebral cortex. Cellular and Molecular Neurobiology, v. 25, n. 5, p. 851-862, 2005.
140. LATINI, Alexandra ; SCUSSIATIO, Karina ; LEIPNITZ, Guilhain ; WAJNER, M. ; DUTRAFILHO, Carlos S . Promotion of oxidative stress by 3-hydroxyglutaric acid in rat striatum. Journal of Inherited Metabolic Disease, v. 28, n. 1, p. 57-67, 2005.
141. LATINI, Alexandra ; SILVA, Cleide Gonçalves da ; FERREIRA, Gustavo C ; SCHUCK, Patrícia F ; SCUSSIATO, Karina ; SARKIS, João J ; DUTRA FILHO, Carlos S ; WYSE, Angela Ts ; WANNMACHER, Clócis M D ; WAJNER, M. . Mitochondrial energy metabolism is markedly impaired by D-2-hydroxyglutaric acid inrat tissues. Molecular Genetics and Metabolism, v. 86, n. 1-2, p. 188-199, 2005.
142. FEKSA, Luciane Rosa ; CORNELIO, Andrea ; DUTRA FILHO, Carlços Severo ; WYSE, Angela T S ; WAJNER, M. ; WANNMACHER, Clovis M D . The effects of the interactions between amino acids on pyruvate kinase activity from brain cortex of young rats. International Journal of Developmental Neuroscience, v. 23, p. 509-514, 2005.
143. LATINI, Alexandra ; RODRIGUEZ, Marianela ; BORBA, Rafael Rosa ; SCUSSIATO, Karina ; LEIPNITZ, Guilhian ; FERREIRA, Gustavo da Costa ; FUNCHAL, Cláudia ; SILVA, Maria Carolina Jacques ; BUZZIN, Luciane ; GIUGLIANI, Roberto ; CASSINA, Adriana ; RADI, Rafael ; WAJNER, M. . 3-Hydroxyglutaric acid moderately impairs energy metabolism in brain of young rats. Neuroscience, v. 135, p. 111-120, 2005.
144. STEFANELLO, Francieli M ; CHIARANI, Fábria ; KUREK, Andréa G ; WANNMACHER, Clóvis Md ; WAJNER, M. ; WYSE, Angela Ts . Methionine alters Na+,K+-ATPase activity, lipid peroxidation andnonenzymatic antioxidant defenses inrat hippocampus. International Journal of Developmental Neuroscience, in press, v. 23, n. 7, p. 651-656, 2005.
145. FUNCHAL, Cláudia ; SANTOS, André Quincozes dos ; JACQUESSILVA, Maria Caroline ; ZAMONER, Ariane ; GOTTFRIED, Carmen ; WAJNER, M. ; PESSOAPUREUR, Regina . Branched-chain alpha-keto acids accumulating in maple syrup urine disease induce reorganization of phosphorylated GFAP in 6 glioma cells. Metabolic Brain Disease, v. 20, n. 3, p. 205-217, 2005.
146. FUNCHAL, Cláudia ; ZAMONER, Ariane ; SANTOS, André Quincozes dos ; MORETTO, Maria Beatriz ; LOUREIRO, Samanta Oliveria ; ROCHA, João Bt ; WAJNER, M. ; PESSOAPUREUR, Regina . Evidence that intracelular Ca 2+ mediates the effect of alpha-ketoisocaproic acid on the phosphorylating system of sytoskeletal proteins from cerebral cortex of immature rats. Journal of the Neurological Sciences, v. 238, n. 1-2, p. 75-82, 2005.
147. FERREIRA, Gustavo da C ; VIEGAS, Carolina M ; SCHUCK, Patrícia ; TONIN, Anelise ; RIBEIRO, C. A. J. ; COELHO, Daniela de M ; DALLACOSTA, Teresa ; LATINI, Alexandra ; WYSE, Angela Ts ; WANNMACHER, Clóvis Md ; WAJNER, M. . Glutaric acid administration impairs energy metabolism in midbrain and skeletal muscle of young rats. Neurochemical Research, v. 30, n. 9, p. 1123-1131, 2005.
148. FUNCHAL, Cláudia ; ZAMONER, Ariane ; SANTOS, André Q dos ; LOUREIRO, Samanta O ; WAJNER, M. ; PUREUR, Regina Pessoa . alpha-ketoisocaproic acid increases phosphorylation of intermediate filament proteins from rat cerebral cortex by mechanisms involving Ca2+ and cAMP. Neurochemical Research, v. 30, n. 9, p. 1132-1146, 2005.
149. FERREIRA, Gustavo C ; VIEGAS, Carolina Maso ; SCHUCK, Patrícia F ; LATINI, Alexandra ; DUTRAFILHO, Carlos S ; WYSE, Angela Ts ; WANNMACHER, Clóvis Md ; WAJNER, M. . Glutaric acid moderately compromises energy metabolism in rat brain. International Journal of Developmental Neuroscience, v. 23, n. 8, p. 687-693, 2005.
150. LEIPNITZ, Guilhian ; SCHUMACHER, Cristiana ; SCUSSIATO, Karina ; DALCIN, Karina B ; WANNMACHER, Clóvis Md ; WYSE, Angela Ts ; DUTRAFILHO, Carlos S ; WAJNER, M. ; LATINI, Alexandfa . Quinolinic acid reduces the antioxidant defenses in cerebral cortex of young rats. International Journal of Developmental Neuroscience, v. 23, n. 8, p. 695-701, 2005.
151. SILVA, C. G. ; BUENO, A. R. F. ; SCHUCK, Patrícia F ; LEIPNITZ, Guilhian ; RIBEIRO, C. A. J. ; ROSA, Rafael B ; DUTRA FILHO, Carlos S ; WYSE, Angela Ts ; WANNMACHER, Clóvis Md ; WAJNER, M. . Inhibition of creatine kinase activity from rat cerebral cortex by D-2-hydroxyglutaric acid in vitro. Neurochemistry International, v. 44, n. 1, p. 45-52, 2004.
152. FRIZZO, Marcos Es ; SCHARZBOLD, C. ; PORCIÚNCULA, Lisiane O ; DALCIN, Karina B ; RIBEIRO, C. A. J. ; SOUZA, Diogo O ; WAJNER, M. . 3-Hydroxyglutaric acid enhances glutamate uptake into astrocytes from cerebral cortex of young rats. Neurochemistry International, v. 44, n. 5, p. 345-353, 2004.
153. WYSE, Angela Ts ; STEFANELLO, Francieli M ; CHIARANI, Fábria ; DELWING, Débora ; WANNMACHER, Clóvis Md ; WAJNER, M. . Arginine administration decreases cerebral cortex acethylcholinesterase and serum butyrylcholinesterase probably by oxidative stress induction. Neurochemical Research, v. 29, n. 2, p. 385-389, 2004.
154. VASQUES, V. C. ; BOER, M. A. ; DILIGENTI, F. ; BRINCO, Fabrício ; MALLMANN, F. ; MELLO, C. F. ; WAJNER, M. . Intrahippocampal administrationof the alpha-keto acids accumulating in maple syrup urine disease provokes learning deficits in rats. Pharmacology, Biochemistry and Behavior, v. 77, n. 1, p. 183-190, 2004.
155. FUNCHAL, Claudia ; PESSUTTO, F. D. B. ; ALMEIDA, L. M. ; PELAEZ, P. L. ; LOUREIRO, Samanta O ; VIVIAN, Lilian ; WAJNER, M. ; PUREUR, Regina Pessoa . Alpha-keto-beta-methylvaleric acid increases the in vitro phosphorylation of intermediate filaments inslices of cerebral cortex of young rats inslices of cerebralcortex of young rats through GABAergic system. Journal of the Neurological Sciences, v. 217, n. 1, p. 17-24, 2004.
156. FUNCHAL, Cláudia ; ROSA, Aline M ; WAJNER, M. ; SOUZA, Diogo O ; SUSANAWOFCHUCK ; PUREUR, Regina P . Reduction of glutamate uptake into cerebral cortex of developing rats by the branched chain alpha-keto acids accumulating in maple syruup urine disease. Neurochemical Research, v. 29, n. 4, p. 747-753, 2004.
157. JUNQUEIRA, D. ; BRUSQUE, A. M. ; PORCIÚNCULA, Lisiane O ; ROTTA, L. N. ; FRIZZO, Marcos Es ; WYSE, A. T. ; WANNMACHER, Clóvis Md ; SOUZA, Diogo O ; WAJNER, M. . In vitro effects of D-2-hydroxyglutaric acid on glutamate binding, uptake and release in cerebral cortex of rats. Journal of the Neurological Sciences, v. 217, n. 2, p. 189-194, 2004.
158. VARGAS, Carmen R ; WAJNER, M. ; SIRTORI, Lisana ; GOULART, L. ; CHIOCHETTA, M. ; COELHO, Daniela ; LATINI, Alexandra ; LESSUY, S. ; BELLÓKLEIN, Adriane ; GIUGLIANI, Roberto ; DEON, M ; MELLO, C. F. . Evidence that oxidative stres is increased in patients with X-linked adrenoleukodystrophy. Biochimica et Biophysica Acta. G, General Subjects, v. 1688, n. 1, p. 26-32, 2004.
159. CORNELIO, Andrea Renata ; RODRIGUES JUNIOR, V. ; WYSE, Angela Ts ; DUTRA FILHO, Carlos S ; WAJNER, M. ; WANNMACHER, Clóvis Md . Tryptophan reduces creatine kinase activity in brain cortex of rats. International Journal of Developmental Neuroscience, v. 22, n. 2, p. 95-101, 2004.
160. TANSINI, C. ; DURIGON, K. ; TESTA, C. G. ; KLEIN, A Belló ; WAJNER, M. ; WAJNER, M ; WANNMACHER, C M D ; WYSE, A T S ; DUTRAFILHO, C S . Effects of histidine and imidazolelactic acid on various parameters of the oxidative stress in cerebral cortex of young rats. International Journal of Developmental Neuroscience, v. 22, n. 2, p. 67-72, 2004.
161. WAJNER, M. ; LATINI, Alexandra ; WYSE, Angela Ts ; DUTRA FILHO, Carlos S . The role of oxidative stress in the neuropathology of organic acidurias: insights from animal studies. Journal of Inherited Metabolic Disease, v. 27, n. 4, p. 427-448, 2004.
162. SCHUCK, P. ; ROSA, Rafael B ; PETTENUZZO, Letícia F ; SITTA, Â. ; WANNMACHER, Clóvis Md ; WYSE, Angela T S ; WAJNER, M. . Inhibition of mitochondrial creatine kinase activity from rat cerebral cortex by methylmalonic acid. Neurochemistry International, v. 45, n. 5, p. 661-667, 2004.
163. ROSA, Tatiana Galetto ; WYSE, Angela Ts ; WAJNER, M. ; WANNMACHER, Clóvis Md . Cysteamine prevents and reverses the inhibition of pyruvate kinase activity caused by cystine in rat heart. Biochimica et Biophysica Acta. Bioenergetics, v. 1689, n. 2, p. 114-119, 2004.
164. FEKSA, Luciane R ; CORNELIO, Amdrea ; DU FILHO, Carlos S ; WYSE, Angela T S ; WAJNER, M. ; WANNMACHER, Clóvis Md . Inhibition of pyruvate kinase activity by cystine in brain cortex of rats. Brain Research, v. 1012, n. 1-2, p. 93-100, 2004.
165. ZUGNO, Alexandra I ; FRANZON, Renata ; CHIARANI, Fábria ; BAVARESCO, Caren S ; WANNMACHER, Clóvis Md ; WAJNER, M. ; WYSE, Angela T S . Evaluation of the mechanisms underlying the inhibitory effect of guanidinoacetate onbrfain Na+, K+-ATPase activity. International Journal of Developmental Neuroscience, v. 22, n. 4, p. 191-196, 2004.
166. BAVARESCO, Cs ; ZUGNO, A I ; TAGLIARI, B ; WANNMACHER, C M D ; WAJNER, M. ; WYSE, A T S . Inhibition of Na+,K+-ATPase activity in rat striatum by the metabolites accumulated in Lesch-Nyhan disease. International Journal of Developmental Neuroscience, v. 22, n. 1, p. 11-17, 2004.
167. ROSA, Rafael B ; SCHWARZBOLD, Carolina ; DALCIN, Karina B ; GHISLENI, Gabrielle C ; RIBEIRO, C. A. J. ; MORETTO, Maria B ; FRIZZO, Marcos Es ; HOFFMANN, Georg F ; SOUZA, Diogo O ; WAJNER, M. . Evidence that 3-hydroxyglutaric acid interacts with NMDA receptors in synaptic plasma membrane from cerebral cortex of young rats. Neurochemistry International, v. 45, n. 7, p. 1087-1094, 2004.
168. PORCIÚNCULA, Lisiane O ; EMANUELLI, Tatiana ; TAVARES, Rejane G ; SCHWARZBOLD, Carolina ; FRIZZO, Marcos Es ; SOUZA, Diogo O ; WAJNER, M. . Glutaric acid stimulates glutamate binding and astrocyte uptake and inhibits vesicular glutamate uptake in forebrain from young rats. Neurochemistry International, v. 45, n. 7, p. 1075-1086, 2004.
169. MACIEL, Evelise N ; KOWALTOWSKI, Alícia J ; SCHWALM, Fábio D ; RODRIGUES, Juliana M ; SOUZA, Diogo O ; VERCESI, Anibal e ; WAJNER, M. ; CASTILHO, Roger F . Mitochondrial permeability transition in neuronal damage promoted by Ca=2 and respiratory chain complex Ii inhibition. Journal of Neurochemistry, v. 90, p. 1025-1035, 2004.
170. WAJNER, M. ; KÖLKER, S ; SOUZA, D O ; HOFFMANN, G F ; MELLO, C F . Modulation of glutamatergic and GABAergic neurotransmission in glutaryl-coA dehydrogenase deficiency. Journal of Inherited Metabolic Disease, v. 27, n. 6, p. 825-828, 2004.
171. ASSIS, Dênis R de ; MARIA, Rita de Cássia ; ROSA, Rafael B ; SCHUCK, Patrícia F ; RIBEIRO, C. A. J. ; FERREIRA, Gustavo C ; DUTRAFILHO, Carlos S ; WYSE, Ângela Ts ; WANNMACHER, Clóvis Md ; PERRY, Marcos L S ; WAJNER, M. . Inhibition of energy metabolism in cerebral cortex of young rats by the medium-chain fatty acids accumulating inMCAD deficiency. Brain Research, v. 1030, p. 141-151, 2004.
172. KOELLER, Dm ; SAUER, S ; WAJNER, M. ; MELLO, Cf de ; GOODMAN, S I ; WOONTNER, M ; MUHLHAUSEN, C ; OKUN, Jg ; KOLKER, S . Animal models for glutaryl-CoA dehydrogenase deficiency. Journal of Inherited Metabolic Disease, v. 27, n. 6, p. 813-818, 2004.
173. PILLA, C. ; CARDOZO, R. F. L. ; DUTRAFILHO, Carlos S ; WYSE, Â. T. S. ; WAJNER, M. ; WANNMACHER, Clóvis M D . Creatine kinase activity from rat brain is inhibited by branched-chain amino acids in vivo. Neurochemical Research, v. 28, n. 5, p. 675-679, 2003.
174. MARQUES, F. O. ; HAGEN, M. E. K. ; PEDERZOLLI, Carolina D ; SGARAVATTI, Angela M ; DURIGON, Karina ; TESTA, Carla G ; WANNMACHER, C. M. D. ; WYSE, Angela T S ; WAJNER, M. ; DUTRA FILHO, Carlos S . Glutaric acid induces oxidative streee in brain of young rats. Brain Research, v. 964, n. 1, p. 153-158, 2003.
175. LEIPNITZ, Guilhain ; SCHUCK, P. L. ; RIBEIRO, C. A. J. ; DALCIN, K. B. ; ASSISS, D. R. ; BARSCHAK, Alethea G ; PULRONIK, V. ; WANNMACHER, Clóvis Md ; WYSE, Angela Ts ; WAJNER, M. . Ethylmalonic acid inhibits mitochondrial creatine kinase activity from cerebral cortex of young rats in vitro. Neurochemical Research, v. 28, n. 5, p. 771-777, 2003.
176. BAVARESCO, Caren S ; CALCAGNOTTO, T. ; TAGLIARI, Bárbara ; DELWING, Daniela ; LAMERS, M. L. ; WANNMACHER, Clóvis Md ; WAJNER, M. ; WYSE, A. T. S. . Brain Na+-K+-ATPase inhibition induced by arginine administration is prevented by vitamins E and C. Neurochemical Research, v. 28, n. 6, p. 825-829, 2003.
177. STRECK, E. L. ; DELWING, Debora ; TAGLIARI, B. ; MATTE, C. ; WANNMACHER, Clovis M D ; WAJNER, M. ; WYSE, Angela Ts . Brain energy metabolism is compromised by the metabolites accumulating in homocystinuria. Neurochemistry International, v. 43, n. 6, p. 597-602, 2003.
178. ROYES, L. F. F. ; FIGHERA, M. R. ; FURIAN, A. F. ; OLIVEIRA, M. S. ; SILVA, L. G. M. ; MALFATTI, C. F. ; SCHNEIDER, P. H. ; BRAGA, A. L. ; WAJNER, M. ; MELLO, C. F. . Creatine protects against the convulsive behavio and lactate production elicited by the intrastriatal injection of methylmalonate. Neuroscience, v. 118, n. 4, p. 1079-1090, 2003.
179. FUNCHAL, Cláudia ; ALMEIDA, Lúcia M V ; LOUREIRO, Samanta O ; VIVIAN, Lilian ; PELAEZ, Priscila de Lima ; PESSUTTO, F. ; ROSA, Aline M ; WAJNER, M. ; PUREUR, Regina P . In vitro phosphorylation of cytoskeletal proteins from cerebral cortex of rats. Brain Research Protocols, v. 11, p. 111-118, 2003.
180. FEKSA, Luciane Rosa ; CORNELIO, Andrea R ; DUTRA FILHO, Carlos S ; WYSE, Angela T S ; WAJNER, M. ; WANNMACHER, Clovis M D . Characterization of the inhibition of pyruvate kinase caused by phenylalanine and phenylpyruvate in rat brain. Brain Research, v. 968, n. 2, p. 199-205, 2003.
181. ÇUTZ, M. G. ; FEKSA, Luciane Rosa ; WYSE, Angela Ts ; DUTRA FILHO, Carlos S ; WAJNER, M. ; WANNMACHER, Clóvis M D . Alanine prevents the in vitro inhibition of glycolysis caused by phenylalanine in brain cortex of rats. Pharmacology, Biochemistry and Behavior, v. 18, n. 1, p. 87-94, 2003.
182. BAVARESCO, Caren S ; CALCAGNOTTO, T. ; TAGLIARI, Bárbara ; DELWING, Daniela ; LAMERS, M. L. ; WANNMACHER, Clóvis Md ; WAJNER, M. ; WYSE, Angela Ts . Brain Na+,K+-ATPase inhibition induced by arginine administration is prevented by vitamins E and C. Neurochemical Research, v. 28, n. 6, p. 825-829, 2003.
183. ASSIS, Dênis R de ; RIBEIRO, C. A. J. ; ROSA, Rafael B ; SCHUCK, Patrícia F ; DALCIN, Karina B ; VARGAS, Carmen R ; WANNMACHER, Clóvis Md ; DUTRA FILHO, Carlos S ; WYSE, Angela Ts ; BRIONES, P. ; WAJNER, M. . Evidence that antioxidants prevent the inhibition of Na+,K+-ATPase activity induced by octanoic acid in rat cerebralcortex in vitro. Neurochemical Research, v. 28, n. 8, p. 1255-1263, 2003.
184. PILLA, C. ; CARDOSO, R. F. O. ; DORNELLES, Paula K B ; DUTRA FILHO, Carlos S ; WYSE, Angela Ts ; WAJNER, M. ; WANNMACHER, Clóvis Md . Kinetic studies on the inhibition of creatine kinase activity by branched-chain alpha-amino acids in the brain cortex of rats. International Journal of Developmental Neuroscience, v. 21, n. 3, p. 145-151, 2003.
185. COSTABEBER, E. ; KESSLER, A. ; DUTRA FILHO, Carlos S ; WYSE, Angela Ts ; WAJNER, M. ; WANNMACHER, Clóvis Md . Hyperphenylalaninemia reduces creatine kinase activity in the cerebral crtex of rats. International Journal of Developmental Neuroscience, v. 21, p. 111-116, 2003.
186. SILVA, C. G. ; BUENO, A. R. F. ; SCHUCK, Patrícia F ; LEIPNITZ, Guilhain ; RIBEIRO, C. ; WANNMACHER, Clóvis Md ; WYSE, Angela Ts ; WAJNER, M. . L-2-hydroxyglutaric acid inhibits mitochondrial creatine kinase activity from cerebellum of developing rats. International Journal of Developmental Neuroscience, v. 21, n. 4, p. 217-224, 2003.
187. WAJNER, M. ; STRECK, E. L. ; MATÊ, C. ; VIEIRA, P. S. ; CALCAGNOTTO, T. ; WANNMACHER, Clóvis M D ; WYSE, Angela Ts . Impairment of energy metabolism in hippocampus of rats subjected to chemically-induced hyperhomocysteinemia. Biochimica et Biophysica Acta. Molecular Basis of Disease, v. 1637, n. 3, p. 187-192, 2003.
188. SILVA, C. G. ; BUENO, A. R. F. ; ROSA, Rafael B ; DUTRA FILHO, Carlos S ; WANNMACHER, Clóvis Md ; WYSE, Angela Ts ; WAJNER, M. . Inhibition of mitochondrial creatine kinase activity by D-2-hydroxyglutaric acid in cerebellum of young rats. Neurochemical Research, v. 28, n. 9, p. 1329-1937, 2003.
189. LATINI, Alexandra ; SCUSSIATO, Karina ; ROSA, Rafael Borba ; LLESUY, Susana ; BELLÓKLEIN, Adriane ; DUTRA FILHO, Carlos S ; WAJNER, M. . D-2-hydroxyglutaric acid induces oxidative stress incerebral cortex of young rats. European Journal of Neuroscience, v. 17, n. 10, p. 2017-2022, 2003.
190. ZUGNO, Alexandra I ; STAFANELLO, F. M. ; STRECK, E. ; CALCAGNOTTO, T. ; WANNMACHER, Clóvis Md ; WAJNER, M. ; WYSE, Angela Ts . Effect of guanidinoacetate on striatum Na+,K+-ATPase and acetylcholinesterase in young rats. International Journal of Developmental Neuroscience, v. 21, n. 4, p. 183-189, 2003.
191. PETTENUZZO, Letícia F ; SCHUCK, Patrícia F ; WYSE, Angela T S ; WANNMACHER, Clóvis Md ; DUTRA FILHO, Carlos S ; ALEXANDRE NETTO, ; WAJNER, M. . Ascorbic acid prevents water maze behavioral deficits caused by early postnatal methylmalonic administration in the rat. Brain Research, v. 976, n. 2, p. 274-242, 2003.
192. GOMEZ, R. ; VARGAS, Carmen R ; WAJNER, M. ; BARROS, H. M. . Lower in vivo extracellular GABA concentration indiabetic rats duringforced swimming. Brain Research, v. 968, p. 281-284, 2003.
193. DELWING, Débora ; TAGLIARI, Bárbara ; STRECK, E. ; WANNMACHER, Clóvis Md ; WAJNER, M. ; WYSE, Angela Ts . Reduction of energy metabolism in rat hyppocampus by arginine administration.. Brain Research, v. 983, n. 1-2, p. 58-63, 2003.
194. RAQUEL, B. ; ARALDI, J. ; SGARBI, M. B. ; TESTA, Carla G ; DURIGON, Karina ; WAJNER, M. ; DUTRA FILHO, Carlos S . Induction of oxidative stress inrat brain by the metabolites accumulating in maple syrup urine disease. International Journal of Developmental Neuroscience, v. 21, n. 6, p. 327-332, 2003.
195. FRANZON, Renata ; LAMERS, M. L. ; STEFANELLO, F. M. ; WANNMACHER, Clóvis Md ; WAJNER, M. ; WYSE, A. T. . Evidence that oxidative stress is involved in the inhibitory effect of proline on Na+K+-ATPase activity in synaptic plasma membrane of rat hippocampus. International Journal of Developmental Neuroscience, v. 21, n. 6, p. 303-307, 2003.
196. ALMEIDA, L. M. ; FUNCHAL, Cláudia ; PELAEZ, P. L. ; PESSUTTO, Franciele D B ; LOUREIRO, Samanta O ; VIVIAN, Lilian ; WAJNER, M. ; PESSOAPUREUR, Regina . Effect of propionic and methylmalonic acids on the in vitro phosphorylation of intermediate filaments from cerebral cortex of rats during development. Metabolic Brain Disease, v. 18, n. 3, p. 207-219, 2003.
197. WAJNER, M. ; JUNQUEIRA, D. ; BRUSQUE, A. M. ; PORCIÚNCULA, Lisiane O ; ROCHA, L. N. ; RIBEIRO, C. A. J. ; FRIZZO, Marcos Es ; DUTRA FILHO, Carlos S ; SOUZA, Diogo O . Effects of L-2-hydroxyglutaric acid on various parameters of the glutamatergic system in cerebral cortex of rats. Metabolic Brain Disease, v. 18, n. 3, p. 233-243, 2003.
198. STEFANELLO, Francieli M ; ZUGNO, Alexandra I ; WANNMACHER, Clóvis Md ; WAJNER, M. ; WYSE, Angela Ts . Homocysteine inhibits butyrylcholinesterase activity in rat serum. Metabolic Brain Disease, v. 18, n. 3, p. 187-194, 2003.
199. KESSLER, A. ; COSTABEBER, E. ; DUTRAFILHO, Carlos S ; WYSE, Angela T S ; WAJNER, M. ; WANNMACHER, Clovis M D . Proline reduces creatine kinase activity in the brain cortex of rats. Neurochemical Research, v. 28, n. 8, p. 1175-1180, 2003.
200. KESSLER, A. ; COSTABEBER, E. ; DUTRA FILHO, Carlos S ; WYSE, A. T. S. ; WAJNER, M. ; WANNMACHER, Clóvis M D . Effect of proline oncreatine kinase activity inrat brain. Metabolic Brain Disease, v. 18, n. 2, p. 169-177, 2003.
201. SILVA, C. G. ; BUENO, A. R. F. ; SCHUCK, Patrícia F ; LEIPNITZ, Guilhian ; RIBEIRO, C. A. J. ; WANNMACHER, Clóvis Md ; WYSE, Angela T S ; WAJNER, M. . D-2-hydroxyglutaric acid inhibits creatine kinase activity from cardiac and skeletal muscle of young rats. European Journal of Clinical Investigation, v. 33, n. 10, p. 840-847, 2003.
202. DELWING, Daniela ; BAVARESCO, Caren Serra ; CHIARANI, Fábria ; WANNMACHER, Clóvis Md ; WAJNER, M. ; DUTRA FILHO, Carlos S ; WYSE, Angela Ts . In vivo andin vitro effects of proline on some parameters of oxidative streee in rat brain. Brain Research, v. 991, n. 1-2, p. 180-186, 2003.
203. PETTENUZZO, Letícia F ; SHUCK, P. F. ; WYSE, Angela Ts ; WANNMACHER, Clóvis Md ; DUTRA FILHO, Carlos S ; A NETTO, C. ; WAJNER, M. . Evaluation of the effect of chronic administration of drugs on rat behavior in the water maze task. Brain Research Protocols, v. 12, n. 2, p. 109-115, 2003.
204. LATINI, Alexandra ; SCUSSIATO, Karina ; BORBA, R. R. ; LEIPNITZ, Guilhain ; LLESSUY, S. ; KLEIN, A. B. ; DUTRA FILHO, Carlos S ; WAJNER, M. . Induction of oxidative stress by L-2-hydroxyglutaric acid in rat brain. Journal of Neuroscience Research, v. 74, n. 1, p. 103-110, 2003.
205. STEFANELLO, Francieli M ; FRANZON, Renata ; WANNMACHER, C. M. ; WAJNER, M. ; WYSE, Angela Ts . In vitro homocysteine inhibits platelet Na+,K+-ATPase and serum butyrylcholinesterase activities of young rats. Metabolic Brain Disease, v. 18, n. 4, p. 273-280, 2003.
206. SGARAVATTI, Angela M ; BORBA, R. B. ; SCHUCK, P. ; RIBEIRO, C. A. J. ; WANNMACHER, Clóvis Md ; WYSE, Angela Ts ; DUTRA FILHO, Carlos S ; WAJNER, M. . Inhibition of brain energy metabolism by the alpha-ketoacids accumulating in maple syrup urine disease. Biochimica et Biophysica Acta. Molecular Basis of Disease, v. 1639, n. 3, p. 232-238, 2003.
207. FONTELLA, Fernanda U ; GASSEN, E. ; PULRONIK, V. ; WANNMACHER, Clóvis M D ; KLEIN, A. ; WAJNER, M. ; DUTRA FILHO, Carlos S . Stimulation of lipid peroxidation in vitro inrat brain by the metabolites accumulating in maple syrup urine disease. Metabolic Brain Disease, v. 17, n. 1, p. 47-54, 2002.
208. SILVA, C. G. ; RIBEIRO, C. A. J. ; LEIPNITZ, Guilhian ; DUTRA FILHO, Carlos S ; WYSE, Angela Ts ; WANNMACHER, Clóvis M D ; SARKIS, J. J. F. ; JAKOBS, C. ; WAJNER, M. . Inhibition of cytochrome c oxidase activity in rat cerebral cortex and human skeletal muscle by D-hydroxyglutaric acid in vitro. Biochimica et Biophysica Acta. Molecular Basis of Disease, v. 1586, n. 1, p. 81-91, 2002.
209. PESOAPUREUR, R. ; FUNCHAL, C. ; VIVIAN, L ; PELAEZ, P. L. ; LOUREIRO, S. ; MIRANDA, R. F. ; WAJNER, M. . Effect of branched-chain alpha-ketoacids accumulating in maple syrup urine disease on the high molecular weight neurofilament subunit (NF-H) in rat cerebral cortex. Metabolic Brain Disease, Estados Unidos, v. 17, n. 2, p. 65-75, 2002.
210. STRECK, E. L. ; ZUGNO, Alexandra I ; TAGLIARI, B. ; WANNMACHER, Clóvis M D ; WAJNER, M. ; WYSE, Angela T S . Inhibition of Na+-K+-ATPase activity by the metabolites accumulating in homocystinuria. Metabolic Brain Disease, v. 17, n. 2, p. 83-91, 2002.
211. BRUSQUE, A. M. ; ROSA, R. R. B. ; SCHUCK, Patrícia F ; DALCIN, K. ; RIBEIRO, C. A. J. ; SILVA, C. G. ; WANNMACHER, Clóvis M D ; DUTRA FILHO, C. ; WYSE, Ângela Ts ; BRIONES, P. ; WAJNER, M. . Inhibition of the mitochondrial respiratory chain complex activities in rat cerebral cortex by methylmalonic acid. Neurochemistry International, v. 40, n. 7, p. 593-601, 2002.
212. KOLKER, Stefan ; OKUN, J. G. ; AHLEMEYER, B. ; WYSE, Angela T S ; HORSTER, F. ; WAJNER, M. ; KOHLMULLER, D. ; MAYATEPEK, E. ; KRIGLSTEIN, J. ; HOFFMANN, Georg F . Chronic treatment with glutaric acid induces partial tolerance to excitotoxicity in neuronal cultures from chick embryo telencephalons. Journal of Neuroscience Research, v. 68, p. 424-431, 2002.
213. TRINDADE, V. M. ; BRUSQUE, A. M. ; RAASCH, J. ; PETTENUZZO, L. ; WANNMACHER, Clóvis M D ; WAJNER, M. . Ganglioside alterations in the central nevous system of rats chronically injected with methylmalonic and propionic acids. Metabolic Brain Disease, v. 17, p. 93-102, 2002.
214. WAJNER, M. ; VARGAS, C. ; FUNAYAMA, C. ; FERNANDEZ, A. ; ELIAS, M. ; GOODMAN, S. I. ; JAKOBS, C. ; VANDERKNAAP, M. . D-2-Hydroxyglutaric aciduria in a patient with severe clinical phenotype and unusual MRI findings. Journal of Inherited Metabolic Disease, v. 25, n. 1, p. 28-34, 2002.
215. ZUGNO, Alexandra I ; TAGLIARI, Bárbara ; SARKIS, J. J. ; WAJNER, M. ; WANNMACHER, Clóvis M D ; WYSE, Ângela Ts . On the mechanism of the inhibition of Na+,K+-ATPase activity caused by homocysteine. International Journal of Developmental Neuroscience, v. 20, p. 77-81, 2002.
216. DELWING, Débora ; DELWING, Daniela ; WANNMACHER, Clóvis M D ; WAJNER, M. ; DUTRA FILHO, Carlos S ; WYSE, Ângela Ts . Arginine administration reduces catalase activity in midbrain of rats. NeuroReport (Oxford), v. 13, n. 10, p. 1301-1304, 2002.
217. RECH, Virginia C ; FEKSA, Luciane R ; DUTRA FILHO, Carlos S ; WYSE, Ângela Ts ; WAJNER, M. ; WANNMACHER, Clóvis M D . Inhibition of mitochondrial respiratory chain complex activity by alanine in rat cerebralcortex. Metabolic Brain Disease, v. 17, n. 3, p. 123-130, 2002.
218. RECH, Virginia C ; FEKSA, Luciane R ; DUTRA FILHO, Carlos S ; WYSE, Ângela Ts ; WAJNER, M. ; WANNMACHER, Clóvis M D . Inhibition of the mitochondrial respiratory chain by phenylalanine in rat cerebral cortex. Neurochemical Research, v. 27, n. 5, p. 353-357, 2002.
219. PETTENUZZO, L. ; SCHUCK, Patrícia F ; FONTELLA, F. ; WANNMACHER, Clóvis M D ; WYSE, Ângela Ts ; DUTRA FILHO, Carlos S ; A NETTO, C. ; WAJNER, M. . Ascorbic acid prevents cognitive deficits caused by chronic administration of propionic acid to rats in the water maze. Pharmacology, Biochemistry and Behavior, v. 73, n. 3, p. 623-629, 2002.
220. DELWING, Débora ; DELWING, Daniela ; WANNMACHER, Clóvis M D ; WAJNER, M. ; DUTRA FILHO, Carlos S ; WYSE, Angela T S . Arginine administration reduces catalase activity in midbrain of rats. NeuroReport (Oxford), v. 13, n. 10, p. 1301-1304, 2002.
221. PILLA, C. ; CARDOZO, R. F. O. ; DUTRA FILHO, Carlos Severo ; WYSE, Angela Ts ; WAJNER, M. ; WANNMACHER, Clóvis M D . Effect of leucine administration on creatine kinase activity in rat brain. Metabolic Brain Disease, v. 18, n. 1, p. 17-25, 2002.
222. WAJNER, M. ; RAYMOND, K. ; BARSCHAK, A. ; LUFT, A. P. ; GUSTAVO ; FERREIRA ; DOMINGUES, G. ; CHIOCHETTA, M. ; SIRTORI, Lisana ; GOULART, L. ; PULRONIK, V. ; PIRES, R. F. ; GRILO, E. ; LOHR, A. ; FUNAYAMA, C. ; SANSEVERINO, M. T. ; COELHO, J. C. ; GIUGLIANI, Roberto ; VARGAS, Carmen R . Detection of organic acidemias in BRazil. Archives of Medical Research, v. 33, n. 6, p. 581-585, 2002.
223. STRECK, E. L. ; MATTÉ, Cristiane ; VIEIRA, P. S. ; ROMBALDI, F. ; WANNMACHER, Clóvis M D ; WAJNER, M. ; WYSE, Angela Ts . Reduction of Na+,K+-ATPase activity in hippocampus of rats subjected to chemically-induce hyperhomocysteinemia. Neurochemical Research, v. 27, n. 12, p. 1585-1590, 2002.
224. WYSE, Angela Ts ; ZUGNO, Alexandra I ; STRECK, E. ; MATTE, C. ; CATAGNOTTO, T. ; WANNMACHER, Clóvis Md ; WAJNER, M. . Inhibition of Na+,K+-ATPase activity in hippocampus of rats subjected to acute administration of homocysteine is prevented by vitamins E and C. International Journal of Developmental Neuroscience, v. 27, n. 12, p. 1677-1681, 2002.
225. SCHUCK, Patrícia F ; LEIPNITZ, Guilhian ; RIBEIRO, C. A. J. ; DALCIN, Karina B ; ASSISS, D. R. ; BARSCHAK, Alethea G ; PULRONIK, V. ; WANNMACHER, Clóvis Md ; WYSE, Â. T. S. ; WAJNER, M. . Inhibition of creatine kinase activity in vitro by ethylmalonic acid in cerebral cortex of young rats. Neurochemical Research, v. 27, n. 12, p. 1625-1631, 2002.
226. FEKSA, Luciane R ; CORNELIO, Andrea R ; RECH, Virginia C ; DUTRAFILHO, Carlos S ; WYSE, Â. T. S. ; WAJNER, M. ; WANNMACHER, Clóvis M D . Alanine prevents the reduction of pyruvate kinase activity in brainocortexo of rats subjected to chemically-induced hyperphenylalaninemia. Neurochemical Research, v. 27, n. 9, p. 947-952, 2002.
227. VIVIAN, L ; PESSUTTO, L. M. D. B. ; LOUREIRO, S Oliveira ; PELAEZ, P. L. ; FUNCHAL, C ; WAJNER, M. ; PESSOAPUREUR, R . Effect of propionic and methylmalonic acids on the high molecular weight neurofilament subunit (NF-H) in rat cerebra lcortex during development. Neurochemical Research, v. 27, n. 12, p. 1691-1697, 2002.
228. RECH, V. C. ; FEKSA, Luciane R ; DUTRAFILHO, Carlos S ; WYSE, Â. T. ; WAJNER, M. ; WANNMACHER, Clóvis Md . Inhibition of the mitochondrial respiratory chain by alanine in rat cerebral cortex. Metabolic Brain Disease, v. 17, n. 3, p. 123-130, 2002.
229. FRIZZO, M. E. S. ; LARA, D. R. ; PROKOPIUK, A. S. ; CVARGAS, C. R. ; SALBEGO, C. G. ; WAJNER, M. ; SOUZA, Diogo Onofre . Guanosine enhances glutamate uptake in brain cortical slices at normal and excitotoxic conditions. Cellular and Molecular Neurobiology, v. 22, n. 3, p. 353-363, 2002.
230. FUNCHAL, Cláudia ; PELAEZ, P. L. ; LOUREIRO, Samanta O ; VIVIAN, Lilian ; PESSUTTO, F. D. B. ; ALMEIDA, Lúcia M V de ; WOFCHUK, S. T. ; WAJNER, M. ; PUREUR, Regina Pessoa . alpha-ketoisocaproic acid regulates phosphorylation of intermediate filaments in postnatal rat cortical slices through ionotropic glutamatergic receptors. Developmental Brain Research, v. 139, p. 267-276, 2002.
231. WYSE, Angela Ts ; DUTRAFILHO, Carlos S ; WAJNER, M. ; WANNMACHER, Clóvis M D . Hyperphenylalaninemia reduces creatine creatine activity in cerebral cortex of rats. International Journal of Developmental Neuroscience, v. 789, 2002.
232. DELWING, Daniela ; BAVARESCO, Caren S ; WANNMACHER, Clóvis M D ; WAJNER, M. ; DUTRAFILHO, Carlos S ; WYSE, Angela Ts . Proline induces oxidative stress in cerebral cortex of rats. International Journal of Developmental Neuroscience, v. 790, p. 1-6, 2002.
233. DELWING, Daniela ; CHIARANI, Fábria ; BAVARESCO, Caren S ; WANNMACHER, C. M. ; WAJNER, M. ; WYSE, Angela Ts . Proline reduces acetylcholinesterase activity in cerebral cortex of rats. Metabolic Brain Disease, v. 18, n. 1, p. 79-86, 2002.
234. WAJNER, M. ; RAYMOND, K. ; BARSCHAK, A. ; LUFT, A. P. ; FERREIRA, G ; DOMINGUES, G. ; CHIOCHETTA, M ; SIRTORI, L ; GOULART, L. ; PULRONIK, V. ; PIRES, R. ; GRILLO, E. ; LOHR, A. ; FUNAYAMA, C. ; SANSEVERINO, M. T. ; LEITE, J. C. L. ; COELHO, J. C. ; GIUGLIANI, R ; VARGAS, C R . Detection of organic acidemias in Brazil. Archives of Medical Research, v. 33, p. 581-585, 2002.
235. WYSE, Â. T. S. ; DELWING, Débora ; CRUSIUS, L. ; TAGLIARI, B. ; DUTRA-FILHO, C. S. ; WANNMACHER, C. M. D. ; WAJNER, M. . Evidence that arginine administration provokes inhibition of catalase activity in the brain. Journal of Inherited Metabolic Disease, v. 25, p. 147, 2002.
236. WANNMACHER, Clovis Milton Durval ; COSTABEBER, E. ; KESSLER, A. ; ARAUJO, C. ; DUTRA-FILHO, C. S. ; WYSE, Â. T. S. ; WAJNER, M. . Hyperphenylalaninemia reduces creatine kinase activity in rats brain. Journal of Inherited Metabolic Disease, v. 25, p. 148, 2002.
237. WAJNER, M. ; PETTENUZZO, Letícia Ferreira ; SCHUCK, Patricia Fernanda ; DALCIN, Karina Borges ; LEIPNITZ, Guilhain ; RIBEIRO, C. A. J. ; LLESUY, Susana ; WANNMACHER, Clovis Milton Durval ; WYSE, Â. T. S. ; BELLÓ-KLEIN, A. ; DUTRA-FILHO, C. S. . Propionic acid administration reduces the antioxidant defenses in rat hippocampus. Journal of Inherited Metabolic Disease, v. 25, p. 149, 2002.
238. LATINI, Alexandra Susana ; SCUSSIATO, Karina ; ROSA, Rafael Borba ; LLESUY, Susana ; KLEIN, A. B. ; WAJNER, M. . D-2-hydroxyglutaric and L-2-hydroxyglutaric acids induce oxidative stress in brain. Journal of Inherited Metabolic Disease, v. 25, p. 152, 2002.
239. WYSE, Â. T. S. ; DELWING, Daniela ; BAVARESCO, Caren Serra ; CALCAGNOTTO, T. ; CHIARANI, Fábria ; DUTRA-FILHO, C. S. ; WANNMACHER, Clovis Milton Durval ; WAJNER, M. . Stimulation of oxidative stress caused by proline in cerebral cortex of rats. Journal of Inherited Metabolic Disease, v. 25, p. 147, 2002.
240. WAJNER, M. ; SCHUCK, Patricia Fernanda ; LEIPNITZ, Guilhian ; DALCIN, Karina Borges ; ASSIS, Denis Reis de ; RIBEIRO, C. A. J. ; BORBA, Rafael Rosa ; WANNMACHER, Clovis Milton Durval ; DUTRA-FILHO, C. S. ; WYSE, Angela Terezinha de Souza . Inhibition of cerebral creatine kinase activity by ethylmalonic acid. Journal of Inherited Metabolic Disease, v. 25, p. 150, 2002.
241. WANNMACHER, Clovis Milton Durval ; PILLA, C. ; CARDOZO, R. F. O. ; DUTRA-FILHO, C. S. ; WISE, A. ; WAJNER, M. . Decreased creatine kinase activity in brain of rats subjected to leucine administration. Journal of Inherited Metabolic Disease, v. 25, p. 148, 2002.
242. RECH, Virginia Cielo ; FEKSA, Luciane Rosa ; DUTRA-FILHO, C. S. ; WYSE, Â. T. S. ; WAJNER, M. ; WANNMACHER, Clóvis Milton Durval . Inhibition of the mitochondrial respiratory chain by phenylalanine in rat cerebral cortex. Neurochemical Research, v. 27, p. 353-357, 2002.
243. WAJNER, M. ; SILVA, C. G. ; BUENO, A. R. F. ; SCHUCK, Patricia Fernanda ; LEIPNITZ, Guilhian ; RIBEIRO, C. A. J. ; RAFAEL, B. R. ; WANNMACHER, Clovis Milton Durval ; DUTRA-FILHO, C. S. ; WISE, A. . D-2-hydroxyglutaric acid compromises brain energy metabolism through inhibition of creatine kinase activity. Journal of Inherited Metabolic Disease, v. 25, p. 146, 2002.
244. WAJNER, M. ; ASSIS, D. R. ; STRECK, E. ; ZUGNO, Alexandra I ; RIBEIRO, C. A. J. ; SCHUCK, Patrícia Fernanda ; LEIPNITZ, Guilhian ; DALCIN, Karina Borges ; WANNMACHER, Clóvis Milton Durval ; DUTRA-FILHO, C. S. ; WYSE, Â. T. S. . Evidence that octanoic acid compromises brain energy metabolism. Journal of Inherited Metabolic Disease, v. 25, p. 149, 2002.
245. ARAUJO, P. ; WASSERMANN, G. F. ; TALLINI, K. ; FURLANETTO, V. ; VARGAS, C R ; WANNMACHER, C M D ; DUTRA FILHO, C S ; WISE, A. T. S. ; WAJNER, M. . Reduction of large neutral amino acid levels in plasma and brain of hyperleucinemic rats. Neurochemistry International, v. 38, p. 529-537, 2001.
246. BRUSQUE, A. M. ; ROTTA, L. ; PETTENUZZO, L F ; JUNQUEIRA, D. ; SCHWARZBOLD, C. V. ; WYSE, A. T. ; WANNMACHER, C M D ; DUTRA FILHO, C S ; WAJNER, M. . Chronic postnatal administration of methylmalonic acid provokes a decrease of myelin content and ganglioside-N-acetylneuraminic acid (NANA) concentration in cerebrum of young rats.. Brazilian Journal of Medical and Biological Research, v. 34, p. 227-231, 2001.
247. COITINHO, A. S. ; FERNANDO, M. C. ; FORTES, T. T. ; BASTIANI, J. ; FIGHERA, M. ; WAJNER, M. . Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats. Brain Research, v. 894, p. 68-73, 2001.
248. SILVA, A. R. ; HELEGDA, C. ; RUSCHEL, C. ; WYSE, Ângela Ts ; WANNMACHER, Clóvis M D ; WAJNER, M. ; DUTRA FILHO, Carlos S . Inhibition of in vitro CO2 production and lipid synthesis by 2-hydroxybutyric acid in rat brain. Brazilian Journal of Medical and Biological Research, v. 34, p. 627-631, 2001.
249. BEDIN, M. ; ESTRELLA, C. H. G. ; PONZI, D. ; DUARTE, D. V. ; DUTRA FILHO, Carlos S ; WYSE, Â. T. S. ; WAJNER, M. ; WANNMACHER, Clóvis M D . Reduced Na+-K+-ATPase activity in erythrocyte membranes from patients with phenylketonuria. Pediatric Research, v. 50, n. 1, p. 56-60, 2001.
250. VARGAS, Carmen R ; BARSCHACK, A. ; COELHO, Daniela ; FURLANETTO, V. ; SOUZA, C. ; KARAM, S. ; JARDIM, Laura ; WAJNER, M. ; GIUGLIANI, Roberto . Clinical and biochemial findings in seven patients with X-linked adrenoleukodystrophy treated with Lorenzo oil. Genetics and Molecular Biology, v. 23, n. 4, p. 697-701, 2001.
251. WYSE, Angela Ts ; BAVARESCO, Caren S ; BANDINELLI, C. ; STRECK, E. ; FRANZON, Renata ; DUTRA FILHO, Carlos S ; WAJNER, M. . Nitric oxide synthase inhibition by L-NAME prevents the decrease of Na+,K+-ATPase activity in midbrain of rats subjected to arginine administration. Neurochemical Research, v. 26, n. 5, p. 515-520, 2001.
252. WAJNER, M. ; BARSCHAK, Alethea ; LUFT, A. P. ; PIRES, Ricardo ; GRILLO, E. ; LOHR, A. ; FUNAYAMA, C. ; SANSEVERINO, M. T. ; GIUGLIANI, Roberto ; VARGAS, Carmen R . Organic acidurias:diagnosis i high-risk Brazilian patients. Jornal de Pediatria, v. 77, n. 5, p. 401-406, 2001.
253. TAVARES, Rejane G ; SANTOS, C. E. ; TASCA, C. I. ; WAJNER, M. ; SOUZA, Diogo O ; DUTRA FILHO, Carlos S . Inhibition of glutamate uptake into synaptic vesicles from rat brain by 3-nitropropionic acid in vitro. Experimental Neurology, v. 172, n. 2, p. 250-254, 2001.
254. STRECK, E. L. ; ZUGNO, Alexandra I ; TAGLIARI, B. ; WANNMACHER, Clóvis M D ; WAJNER, M. ; WYSE, Angela Ts . Inhibition of rat brain Na+, K+,ATPase activity induced by homocysteine is probably mediated by oxidative stress. Neurochemical Research, v. 26, n. 11, p. 1195-2000, 2001.
255. MELLO, C. F. ; KOLKER, Stefan ; AHLEMEYER, B. ; SOUZA, F. R. ; FIGHERA, M. R. ; MAYATEPEK, E. ; KRIEGLSTEIN, J. ; HOFFMANN, Georg ; WAJNER, M. . Intrastriatal administration of 3-hydroxyglutaric acid induces convulsions and striatal lesions in the rats. Brain Research, v. 916, n. 1-2, p. 70-75, 2001.
256. BRUSQUE, A. M. ; ROTTAA, L. ; TAVARES, R. R. ; EMANUELLI, T. ; SCHARZBOLD, C. V. ; DUTRA FILHO, Carlos Severo ; WANNMACHER, Clóvis M D ; SOUZA, Diogo O ; WAJNER, M. . Effects of methylmalonic and propionic acids on glutamate uptake by synaptosomes and synaptic vesicles and on glutamate release by synaptosomes from cerebral cortex of rats. Brain Research, v. 920, n. 1-2, p. 194-201, 2001.
257. VARGAS, Carmen R ; FUNAYAMA, C. ; FERNANDEZ, A. ; ELIAS, M. M. L. ; GOODMAN, S. ; JAKOBS, C. ; KNAAP, M. V. D. ; WAJNER, M. . Intermittent D-hydroxyglutaric aciduria in a patient with a severe clinical phenotype and extensive white matter changes on MRI. Journal of Inherited Metabolic Disease, 2001.
258. VARGAS, Carmen R ; WAJNER, M. . Acidúrias orgânicas: diagnóstico e tratamento. Revista AMRIGS, 2001.
259. SILVA, A. ; GONÇALEVES, C. S. ; HELEGDA, C. ; WYSE, Angela Ts ; WANNMACHER, Clóvis M D ; WAJNER, M. ; DUTRA FILHO, Carlos S . Pyroglutamic acid inhibits energy production and lipid synthesis in vitro incerebral cortex of rats. Neurochemical Research, v. 26, n. 12, p. 1277-1283, 2001.
260. WYSE, Angela Ts ; BAVARESCO, Caren S ; HAGEN, M. E. K. ; DELWING, Daniela ; WANNMACHER, Clóvis M D ; DUTRA FILHO, Carlos S ; WAJNER, M. . In vitro stimulation of oxidative stres in cerebral cortex of rats by guanidino compounds accumulating in hyperargininemia. Brain Research, v. 923, n. 1-2, p. 50-57, 2001.
261. PESOAPUREUR, R. ; FUNCHAL, Cláudia ; PELAEZ, P. L. ; VIVIAN, L ; LOUREIRO, S. O. ; MIRANDA, R. F. ; WAJNER, M. . The effect of branched-chain alpha-ketoacids accumulating in maple syrup urine disease on the high molecular weight neurofilament subunit (NH-F) in rat cerebral cortex. Metabolic Brain Disease, 2001.
262. PONTES, Z. L. ; OLIVEIRA, L. S. ; FRANZON, Renata ; WAJNER, M. ; WANNMACHER, Clóvis M D ; WYSE, Angela Ts . Inhibition of Na+-K+-ATPase activity from rat hippocampus by proline. Neurochemical Research, v. 26, n. 12, p. 1321-1326, 2001.
263. HAGEN, M. E. K. ; PEDERZOLLI, Carolina D ; SGAVARATTI, A. M. ; BRIDI, Raquel ; WAJNER, M. ; WANNMACHER, Clóvis M D ; WYSE, Angela Ts ; DUTRA FILHO, Carlos S . Experimental phenylketonuria provokes oxidative stress in rat brain. Biochimica et Biophysica Acta. Molecular Basis of Disease, v. 1586, n. 3, p. 344-352, 2001.
264. COELHO, J. C. ; BURIN, M. G. ; WAJNER, M. ; VARGAS, Carmen R ; SOUZA, F. T. ; GIUGULIANI, R. . Selective screeening of 18,000 high-risk Brazilian patients for the detection of inborn errors of metabolism. Revista do HCPA & Faculdade de Medicina da Universidade Federal do Rio Grande do Sul, v. 21, n. 3, p. 286-293, 2001.
265. WAJNER, M. ; VARGAS, Carmen R ; BURIN, M. ; GIUGLIANI, Roberto ; COELHO, J. C. . Investigação de eros inatos do metabolismo. Revista do HCPA & Faculdade de Medicina da Universidade Federal do Rio Grande do Sul, v. 21, n. 3, p. 343-361, 2001.
266. WANNMACHER, Clovis Milton Durval ; FEKSA, Luciane Rosa ; CORNELIO, Andrea Renata ; RECH, Virginia Cielo ; DUTRA-FILHO, C. S. ; WYSE, Â. T. S. ; WAJNER, M. . Decrease of pyruvate kinase activity in cerebral cortex of hyperphenilalaninemic rats. Journal of Inherited Metabolic Disease, v. 24, p. 135, 2001.
267. WANNMACHER, C. ; BURGER, Christiane ; WAJNER, André ; KLEIN, D. R. ; DUTRAFILHO, Carlos Severo ; WAJNER, M. ; WYSE, Angela Terezinha de Souza . Alanine prevents the inhibition of Na+,K+-ATPase by metabolites accumulating in maple syrup urine disease. Journal of Inherited Metabolic Disease, v. 24, p. 134, 2001.
268. STRECK, E. ; ZUGNO, Alexandra I ; FRANZON, Renata ; TAGLIARI, Bárbara ; SARKIS, João J ; WAJNER, M. ; WANNMACHER, Clóvis Milton Duval ; WYSE, Angela Terezinha Souza . Kinetic studies on Na+,K+-ATPase activity inhibition caused by homocysteine. Journal of Inherited Metabolic Disease, v. 24, p. 133, 2001.
269. MARQUES, Fernanda de Oliveira ; HAGEN, M. E. K. ; PEDERZOLLI, Carolina Dinonet ; SGARAVATTI, Angela Malysz ; WANNMACHER, Clóvis Milton Duval ; WYSE, Angela Terezinha Souza ; WAJNER, M. ; DUTRAFILHO, Carlos Severo . Glutaric acid induces oxidative stress in brain of young rats. Journal of Inherited Metabolic Disease, v. 24, p. 132, 2001.
270. WYSE, Angela Terezinha Souza ; BAVARESCO, Caren Serra ; HAGEN, M. E. K. ; DELWING, Daniela ; DELWING, Debora ; WAJNER, M. ; WANNMACHER, Clóvis Milton Duval ; DUTRAFILHO, Carlos Severo . Effect of guanidino compounds accumulating in hyperagininemia on oxidative stress in rat brain. Journal of Inherited Metabolic Disease, v. 24, p. 129, 2001.
271. VARGAS, Carmen Regia ; WAJNER, M. ; GIUGLIANI, Roberto ; PIRES, R. F. ; FUNAYAMA, C. ; GRILLO, E. ; GIBSON, K. M. . Increased incidence of 3-hydroxy-3-methylglutaric aciduria in Brazil. Journal of Inherited Metabolic Disease, v. 24, p. 62, 2001.
272. VARGAS, Carmen Regla ; WAJNER, M. ; FUNAYAMA, C. ; FERNANDEZ, A. ; ELIAS, M. L. C. ; GOODMAN, S. I. ; JAKOBS, C. ; KNAAP, M. V. D. . Intermitent excretion of D-2-hydroxyglutaric acid. Journal of Inherited Metabolic Disease, v. 24, p. 61, 2001.
273. BRUSQUE, A. M. ; RAFAEL, B. R. ; SCHUCK, Patricia Fernanda ; DALCIN, Karina Borges ; CMD, W. ; DUTRAFILHO, Carlos Severo ; WYSE, Angela Terezinha Souza ; BRIONES, P. ; WAJNER, M. . Methylmalonic acid inhibits activitis of the respiratory chain complexes in rat brain. Journal of Inherited Metabolic Disease, v. 24, p. 136, 2001.
274. FUNCHAL, Cláudia da Silva ; PELZEZ, P. D. ; MIRANDA, R. F. ; VIVIAN, Lilian ; LOUREIRO, Samata Oliveira ; WAJNER, M. ; PESSOAPUREUR, Regina . Ontogenetic study of the effect of alpha-ketoisocaproate on the in vitro phosphorylation of cytoskeletal proteins from. Journal of Neurochemistry, v. 78, p. 93, 2001.
275. COELHO, J. ; BURIN, M. ; WAJNER, M. ; VARGAS, Carmen Regla ; SOUZA, F. T. ; GIUGULIANI, R. . Selective screeening of 18,000 high-risk Brazilian patients for the detection of inborn errors of metabolism. Revista do HCPA & Faculdade de Medicina da Universidade Federal do Rio Grande do Sul, v. 21, p. 286-293, 2001.
276. KOLKER, Stefan ; MELLO, C. F. ; AHLEMEYER, B. ; LIMA, T. T. F. ; FIGHERA, M. R. ; MAYATEPEK, E. ; KRIEGLSTEIN, J. ; HOFFMANN, Georg F ; WAJNER, M. . Intrastriatal administration of 3-hydroxyglutarate induces convulsions and excitotoxic lesions in rats. Journal of Inherited Metabolic Disease, v. 24, p. 139, 2001.
277. WAJNER, M. ; SILVA, Cleide Gonçalves da ; RIBEIRO, C. A. J. ; LEIPNITZ, Guilhian ; DUTRAFILHO, Carlos Severo ; WYSE, Angela Terezinha Do Souza ; WANNMACHER, Clóvis Milton Duval . Inhibition of cytochrome oxidase activity in rat cerebral cortex and human skeletal muscle by D-2-hydroxyglutaric acid in vitro. Journal of Inherited Metabolic Disease, v. 24, p. 140, 2001.
278. SILVA, A. ; HELEGDA, C. ; BRUSQUE, A. M. ; WANNMACHER, Clóvis M D ; WAJNER, M. ; DUTRA FILHO, Carlos S . Inhibition of rat brain lipid synthesis in vitro by 4-hydroxybutyric acid. . Metabolic Brain Disease, v. 14, n. 3, p. 157-164, 2000.
279. PORCIÚNCULA, Lisiane ; DALPIZZOL JR, A. ; COITINHO, A. S. ; EMANUELLI, Tatiana ; SOUZA, D. ; WAJNER, M. . Inhibition of synaptosomal [3h] glutamate uptake and [3h] glutamate binding to plasma membranes from brain of young rats by glutaric acid. in vitro. Journal of the Neurological Sciences, v. 173, p. 93-96, 2000.
280. MATTOSDUTRA, Â. ; MEIRELLES, R. ; ROCHA, B. B. ; ALBUQUERQUE, T. K. ; WOFCHUK, S. T. ; WAJNER, M. ; PUREUR, Regina Pessoa . Methylmalonic and propionic acids increase the in vitro incorporation of 32p into cytoskeletal proteins from cerebral cortex of young rats through nmda glutamate receptors.. Brain Research, v. 856, p. 111-118, 2000.
281. FONTELLA, F. ; PULRONIK, V. ; GASSEN, E. ; WANNMACHER, Clóvis M D ; KLEIN, A. B. ; WAJNER, M. ; DUTRA FILHO, Carlos S . Propionic acid and l-methylmalonic acid induce oxidative stress on brain of young rats.. NeuroReport (Oxford), v. 11, n. 3, p. 541-544, 2000.
282. TAVARES, R. G. ; TASCA, C. I. ; SANTOS, C. E. S. ; WAJNER, M. ; SOUZA, D. ; DUTRA FILHO, Carlos S . Quinolinic acid inhibits glutamate uptake into synaptic vesicles from rat brain.. NeuroReport (Oxford), v. 11, n. 2, p. 249-253, 2000.
283. WAJNER, M. ; COELHO, D M ; BARSCHAK, Alethea G ; ARAÚJO, P. R. ; PIRES, R. F. ; LULHIER, F. L. G. ; VARGAS, C R . Reduction of large neutral aminoacid concentrations in plasma and CSF of patients with maple urine disease during crises.. Journal of Inherited Metabolic Disease, v. 23, p. 505-512, 2000.
284. WYSE, Angela T S ; STRECK, E. L. ; BARROS, S. V. ; BRUSQUE, A. M. ; ZUGNO, Alexandra I ; WAJNER, M. . Methylmalonate administration decreases na+,K+-ATPase activity in cerebral cortex of rats. NeuroReport (Oxford), v. 11, n. 10, p. 2331-2334, 2000.
285. SANSEVERINI, M. T. ; WAJNER, M. ; GIUGLIANI, Roberto . Application of a clinical and laboratory protocol for the investigation of inborn errors of metabolism among critically-ill children. Jornal de Pediatria, v. 76, n. 5, p. 375-382, 2000.
286. BEDIN, M. ; ESTRELLA, C. ; DUARTE, D. ; PONZI, D. ; DUTRA FILHO, Carlos S ; WISE, A. ; WAJNER, M. ; WANNMACHER, Clóvis M D . Platelet Na+,K+-ATPase activity as a possible peripheral marker for the neurotoxic effects of phenylalanine in phenylketonuria. Metabolic Brain Disease, v. 15, n. 2, p. 115-121, 2000.
287. SILVA, C. G. ; SILVA, A. R. ; RUSCHEL, C. ; HELGEDA, C. ; WISE, A. T. S. ; WANNMACHER, C M D ; WAJNER, M. . Inhibition of energy production in vitro by glutaric acid in cerebral cortex of young rats. Metabolic Brain Disease, v. 15, n. 2, p. 123-131, 2000.
288. TAVARES, R. ; SANTOS, C. ; TASCA, C. ; WAJNER, M. ; SOUZA, D O ; DUTRA FILHO, C S . Inhibition of glutamate uptake into synaptic vesicles from rat brain by 3-nitropropionic acid in vitro. Journal of the Neurological Sciences, v. 173, n. 93, 2000.
289. BRANCO, T. ; MEIRELLES, R. ; ROCHA, B. B. ; MATTOSDUTRA, A. ; WAJNER, M. ; PESSOA, R. P. . Alpha-ketoisocaaproate increases the in vitro 32P incorporation into intermediate filaments in cerebral cortex of rats. NeuroReport (Oxford), v. 11, p. 3546-3550, 2000.
290. TAVARES, Rejane G ; SANTOS, C. E. ; TASCA, C. I. ; WAJNER, M. ; SOUZA, Diogo O ; DUTRA FILHO, Carlos S . Inhibition of glutamate uptake into synaptic vesicles of rat brain by the metabolites accumulating in maple syrup urine disease. Journal of the Neurological Sciences, v. 181, n. 1-2, p. 44-49, 2000.
291. WYSE, Angela Terezinha Souza ; PONTES, Z. L. ; OLIVEIRA, L. S. ; BAVARESCO, Caren Serra ; FRANZON, Renata ; WAJNER, M. ; WANNMACHER, Clóvis Milton Duval . Hyperprolinemia reduces Na+,K+-ATPase activity in rat hippocampus. Journal of Inherited Metabolic Disease, v. 23, p. 82, 2000.
292. WYSE, Angela Terezinha Souza ; BAVARESCO, Caren Serra ; STRECK, E. L. ; ZUGNO, Alexandra I ; BANDINELLI, C. ; WANNMACHER, Clóvis Milton Duval ; WAJNER, M. . Reduction of Na+,K+-ATPase activity in the midbrain of rats subjected to arginine administration is prevented by L-NAME. Journal of Inherited Metabolic Disease, v. 23, p. 83, 2000.
293. DUTRAFILHO, Carlos Severo ; TAVARES, Rejane G ; SANTOS, C. E. S. ; TASCA, C. I. ; WAJNER, M. ; SOUZA, D O . Inhibition of glutamate uptake into synaptic vesicles of rat brain by the metabolites accumulating in maple syrupe urine disease. Journal of Inherited Metabolic Disease, v. 23, p. 81, 2000.
294. WAJNER, M. ; ARAUJO, P. ; TALLINI, K. ; FURLANETTO, V. ; VARGAS, Carmen Regla ; WANNMACHER, Clóvis Milton Duval ; DUTRAFILHO, Carlos Severo ; WYSE, Angela Terezinha Souza ; WASSERMANN, G. F. . Reduction of large neutral amino acid (LNAA) levels in plasma and brain of hyperleucinemic rats. Journal of Inherited Metabolic Disease, v. 23, p. 82, 2000.
295. WAJNER, M. ; COITINHO, A. S. ; LIMA, T. T. F. ; BASTIANI, J. ; FIGHERA, M. R. ; MELLO, C. F. . Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic mechanisms. Journal of Inherited Metabolic Disease, v. 23, p. 83, 2000.
296. WAJNER, M. ; BRANCO, T. ; MEIRELLES, R. ; ROCHA, B. B. ; MATTOSDUTRA, Â. ; PESSOAPUREUR, Regina . Alpha-ketoisocaproic acid increases phosphorylation of intermediate filaments from rat cerebral cortex in vitro. Journal of Inherited Metabolic Disease, v. 23, p. 84, 2000.
297. SILVA, C. G. ; PAROLO, E. ; NORILER, M. E. ; STRECK, E. L. ; WAJNER, M. ; WANNMACHER, Clóvis M D ; WYSE, A. T. S. . In Vitro Inhibition Of Na+,K+-Atpase Activity From Rat Cerebral Cortex By Guanidino Compounds Accumulating In Hyperargininemia. Brain Research, Estados Unidos, v. 838, n. 1-2, p. 78-84, 1999.
298. WYSE, A. T. S. ; NORILER, M. E. ; BORGES, L. F. ; FLORIANO, P. J. ; SILVA, C. G. ; WAJNER, M. ; WANNMACHER, Clóvis M D . Alanine Prevents The Decrease Of Na+, K+-Atpase In Experimental Phenylketonuria. Pharmacology, Biochemistry and Behavior, Estados Unidos, v. 14, n. 2, p. 95-101, 1999.
299. BRUSQUE, A. M. ; MELLO, C. F. ; BUCHANAN, D. N. ; TERRACIANO, S. T. ; VARGAS, C. R. ; WANNMACHER, Clóvis M D ; WAJNER, M. . Effect Of Chemically-Induced Propionic Acidemia On Neurobehavioral Development Of Rats. Pharmacology, Biochemistry and Behavior, Estados Unidos, v. 64, p. 529-534, 1999.
300. WAJNER, M. ; SANTOS, K. D. ; SCHLOTTFELDT, J. L. ; ROCHA, M. P. ; WANNMACHER, C. M. D. . Inhibition Of Mitogen-Activated Proliferation Of Human Peripheral Lymphocytes "In Vitro" By Propionic Acid.. Clinical Science, v. 96, n. 1, p. 99-103, 1999.
301. MELLO, C. F. ; FEKSA, L. ; BRUSQUE, A. M. ; WANNMACHER, C. M. D. ; WAJNER, M. . Chronic Early Leucine Administration Induces Behavioral Deficits In Rats. Life Sciences, v. 65, n. 8, p. 747-755, 1999.
302. FIGHERA, M. R. ; STRACKE, M. P. ; GONZALES-RODRIGUEZ, L. ; QUEIROZ, C. ; FRUSSA-FILHO, R. ; WAJNER, M. ; MELLO, C. F. . Ascorbic Acid And Alpha-Tocopherol Attenuate Methylmalonic Acid-Induced Convulsions. NeuroReport (Oxford), v. 10, n. 10, p. 2039-2043, 1999.
303. WAJNER, M. ; VARGAS, C. R. . Reduced Levels Of Large Neutral Amino Acids (Lnaa) In Plasma Of Patients With Maple Syrup Urine Disease. Archives of Disease in Childhood, v. 80, n. 6, p. 579-579, 1999.
304. SILVA, A. R. ; RUSCHEL ; HELEGDA, C. ; BRUSQUE, M. ; WANNMACHER, C M D ; WAJNER, M. ; DUTRA FILHO, C S . Inhibition of rat brain lipid synthesis in vitro by 4-hydroxybutyric acid.. Metabolic Brain Disease, v. 14, n. 3, p. 157-161, 1999.
305. BRUSQUE, A. M. ; TERRACIANO, S. T. ; FONTELLA, F. U. ; VARGAS, C. R. ; SILVA, C. G. ; WISE, A. T. S. ; TRINDADE, V. T. ; WANNMACHER, Clóvis M D ; WAJNER, M. . Chronic Administration Of Propionic Acid Reduces Ganglioside N-Acetylneuraminic Acid (G-Neuac) Concentration In Cerebellum Of Young Rats.. Journal of the Neurological Sciences, v. 158, p. 121-124, 1998.
306. PORCINCULA, L. O. ; COITINHO, A. S. ; VIEIRA, G. ; DAL-PIZZOL JR, A. ; EMANUELLI, T. ; SOUZA, D. O. G. ; WAJNER, M. . Glutaric Acid Increases 3h-Glutamate Binding Through Selective Ionotropic And Metabotropic Receptors In Brain. Journal of Inherited Metabolic Disease, v. 21, p. 38, 1998.
307. MATTOS-DUTRA, A. ; FREITAS, M. S. ; WAJNER, M. ; PESSOA-PUREUR, R. . Propionic And Methylmalonic Acids Inhibit The In Vitro Phosphorylation Of A 85 Kda Cytoskeletal Protein From Cerebral Cortex Of Rats. Neurochemistry International, ESTADOS UNIDOS, v. 33, n. 5, p. 407-414, 1998.
308.   WYSE, Angela Ts ; WAJNER, M. ; CMD, W. . Kinetics Of Alanine Reversal Of The Inhibition Of Na+,K+-Atpase Activity By Phenylalanine And Phenyllactate In Synaptic Plasma Membrane From The Cerebral Cortex Of Rats. Medical Science Research, v. 26, n. 2, p. 141-143, 1998.
309. WYSE, Angela T S ; SILVA, C. ; BRUSQUE, A. M. ; STRECK, E. ; WAJNER, M. ; CMD, W. . Inhibition Of Na+, K+-Atpase From Rat Brain By Propionic Acid. NeuroReport (Oxford), v. 9, n. 8, p. 1719-1721, 1998.
310. MATTOSDUTRA, A. ; FREITAS, M. S. ; LISBOA, C. S. ; PUREUR, Regina Pessoa ; WAJNER, M. . Effects Of Acute And Chronic Administration Of Methylmalonic And Propionic Acids On The In Vitro Incorporation Of 32p Into Cytoskeletal Proteins From The Cerebral Cortex Of Young Rats. Neurochemistry International, v. 33, n. 1, p. 75-82, 1998.
311. BEGNINI, J. L. T. ; WAJNER, M. ; BASTIANI, J. ; JURACH, A. ; CF, M. . Pharmacological Evidence Of Glutamaergic And Gabaergic Involvement In The Convulsant And Behavioral Effects Of Glutaric Acid. Brain Research, v. 802, n. 1-2, p. 55-60, 1998.
312.   RUBIN, M. M. C. ; WAJNER, M. ; WAJNER, M. C. J. S. D. . Effects Of Methylmalonate And Propionate On [3h] Glutamate Binding, Adenylate Cyclase Activity And Lipid Biosynthesis In Cerebral Cortex Of Rats. Biochemistry and Molecular Biology International, v. 42, n. 6, p. 1143-1150, 1997.
313. WAJNER, M. ; JC, C. . Neurological Dysfuntion In Methylmalonic Acidemia Is Probably Related To The Inhibitory Effect Of Methylmalonate On Brain Energy Production. Journal of Inherited Metabolic Disease, v. 20, n. 6, p. 761-768, 1997.
314. SANTOS, K. D. ; ROCHA, M. ; WANNMACHER, Clóvis M D ; WAJNER, M. . The influence of organic acids on the proliferation of human peripheral lymphocytes activated by concanavalin A and pokeweed mitogen. International Journal of Immunopharmacology, v. 18, n. 12, p. 761-769, 1997.
315. PEREIRA, M. ; CONCEIÇÃO, G. ; COELHO, J. C. ; WAJNER, M. ; GIUGLIANI, R. . Detection Of Metabolic Disorders In High Risk Patients: A Pilot Study In Salvador, Bahia. Arquivos de Neuropsiquiatria, v. 55, n. 2, p. 209-212, 1997.
316.   COELHO, J. C. ; WAJNER, M. ; BURIN, M. ; VARGAS, Carmen R ; GIUGLIANI, Roberto . Selective Screening Of 10,000 High-Risk Brazilian Patients For The Detection Of Inborn Errors Of Metabolism. European Journal of Pediatrics, v. 156, n. 8, p. 650-654, 1997.
317. MATTOS-DUTRA, A. ; FREITAS, M. ; SCHROEDER, N. ; ZILLES, A. Z. ; WAJNER, M. ; PESSOA-PUREUR, R. . Methylmalonic Acid Reduces The In Vivo Phosphorylation Of Cytoskeletal Proteins In The Cerebral Cortex Of Rats. Brain Research, v. 763, n. 2, p. 211-231, 1997.
318. BRUSQUE, A. M. ; DUTRA FILHO, Carlos S ; MALFUSSI, H. ; ROCHA, M. ; WANNMACHER, Clóvis M D ; WAJNER, M. . Propionic Acid Inhibits In Vivo Co2 Production In Cerebellum And Cerebral Cortex Of Suckling Rats. Medical Science Research, v. 25, n. 5, p. 347-349, 1997.
319. MATTOSDUTRA, A. ; FREITAS, M. ; WAJNER, M. ; PUREUR, Regina P . In Vitro Phosphorylation Of Cytoskeletal Proteins In The Cerebral Cortex Is Decreased By Propionic Acid. Experimental Neurology, v. 147, n. 2, p. 238-247, 1997.
320. CKLEES, K. ; HENRIQUES, A. S. J. ; PERES, N. ; NARDI, N. ; WAJNER, M. . Reduction Of Mitogen-Induced Responsiveness Of Human And Murine Lymphocytes In Vitro By Yohmbine And Corynanthine. International Journal of Immunopathology and Pharmacology, v. 9, n. 2, p. 59-65, 1996.
321. MELLO, C. F. ; GEGNINI, J. ; JIMENEZBERNAL, R. ; RUBIN, M. ; BASTIANI, J. ; COSTA, E. ; WAJNER, M. . Intrastriatal Methylmalonic Administration Induces Rotational Behavior And Convulsions Through Glutamatergic Mechanisms. Brain Research, v. 721, n. 1-2, p. 120-125, 1996.
322. CKLESS, K. ; WAJNER, M. ; PASQUAL, M. S. J. ; MOYNA, P. ; WAJNER, M. H. J. . Inhibition Of In Vitro Lymphocyte Transformation By The Isoquinoline Alkaloid Berberine. Journal of Pharmacy and Pharmacology, v. 47, p. 1029-1031, 1995.
323. WAJNER, M. ; CMD, S. M. F. M. J. L. W. . Inhibition Of Mytogen-Activated Proliferation Of Human Lymphocytes In Vitro By High Concentrations Of Glutamine. Arquivos de Biologia e Tecnologia, v. 38, p. 417-427, 1995.
324. WAJNER, M. D. C. ; WAJNER, M. ; GASSEN, E. ; CANDIAGO, R. ; WILHELMES, A. ; MALFUSSI, I. ; CMD, W. . Effect Of Organic Acids On In Vitro Glucose Oxidation By Cerebral Cortex Of Young Rats. Medical Science Research, v. 23, p. 25-26, 1995.
325. BOLOGNESISM, G. W. A. ; WAJNER, M. ; WAJNER, M. B. A. ; CMD, W. . Na+, K+ Atpase Activity In The Synaptic Plasma Membrane From Cerebral Cortex Of Rats Subjected To Chemiclly-Induced Phenylketonuria. Medical Science Research, v. 23, p. 261-262, 1995.
326. WAJNER, M. ; SCHLOTTFELDT, J. ; CKLESS, K. ; CMD, W. . Immunosupressive Effects Of Organic Acids Accumulating In Patients With Mapple Syrup Urine Disease. Journal of Inherited Metabolic Disease, v. 18, p. 165-168, 1995.
327. WAJNER, M. D. C. ; WAJNER, M. ; GASSEN, E. W. C. ; CANDIAGO, R. ; WILHELMS, A. ; IH, M. . 2-Hydroxybutyrate And 4-Hydroxybutirate Inhibit Co2 Formation From Labeled Substrates By Rat Cerebral Cortex. Biochemical Society Transactions, v. 23, p. 228-229, 1995.
328. WAJNE, M. D. C. ; WAJNER, M. ; GASSEN, E. W. C. ; IH, C. R. W. A. M. . Inhibition Of Citrate Oxidation In Vitro By 2-Hydroxybutyrate And 4-Hydroxybutyrate In Cerebral Cortex Of Young Rats. Biochemical Society Transactions, v. 23, p. 229-230, 1995.
329. MELLO, C. F. ; PIZUTI, R. ; LOPES, A. ; RUBIN, M. ; SOMER, J. ; VEGA, P. L. ; SOUZA, D. ; WAJNER, M. . Neurochemical Effects Of L-Pyroglutamic Acid. Neurochemical Research, v. 20, n. 12, p. 1437-1442, 1995.
330. CKLESS, K. ; SCHLOTTFELDT, J. ; PASQUAL, M. ; MOYNA, P. ; HENRIQUES, J. P. ; WAJNER, M. . Inhibition Of In Vitro Lymphocyte Transformation By The Isoquinoline Alkaloid Berberine. Journal of Pharmacy and Pharmacology, v. 47, p. 1029-1031, 1995.
331. ROCHA, M. ; PIRES, A. A. ; GRIEBLER, P. ; BLAZINA, L. R. ; WANNMACHER, Clóvis M D ; WAJNER, M. . Efeito Imunosupressor In Vitro do Ácido Alfa-Cetoisocapróico. Revista do HCPA & Faculdade de Medicina da Universidade Federal do Rio Grande do Sul, v. 15, p. 22-24, 1995.
332. SCHLOTTFELDT, J. ; SANTOS, K. ; WAJNER, M. . Effect Of Mevalonate On Invitro Reactivity Of Human Lymphocytes Stimulated By Phytohemaglutinin, Concavalin A And Pokeweed Mitogen. Ciência e Cultura (SBPC), v. 47, p. 189-192, 1995.
333. SCHLOTTFELDT, J. ; BLAZINA, L. ; WANNMACHER, Clóvis M D ; WAJNER, M. . The Effect Of Organic Acids On Phytohemaglutinin-Activated Proliferation Of Human Lymphocytes In Vitro. International Journal of Immunopharmacology, v. 17, n. 3, p. 175-182, 1995.
334. DUTRA-FILHO, C. S. ; WAJNER, M. ; WANNMACHER, C. ; GASSEN, E. ; CANDIAGO, R. ; WILHELMS, A. ; MALFUSSI, H. . Inhibition Of Citrate Oxidation In Vitro By 2-Hydroxybutyrate And 4-Hydroxybutyrate In Cerebral Cortex Of Young Rats. Biochemical Society Transactions, v. 23, p. 229-230, 1995.
335. SARKIS, J. J. F. ; CUNHAFILHO, J. ; TEIXEIRA, M. V. ; SCHETIINGER, M. R. ; WAJNER, M. ; CMD, W. . Atp Diphosphohydrolase Activity In Synaptosomes From Cerebral Cortex Of Rats Subjected To Chemically-Induced Phenylketonuria. Brazilian Journal of Medical and Biological Research, v. 28, p. 1029-1031, 1995.
336. WYSE, Angela ; WAJNER, M. ; BRUSQUE, A. M. ; WANNMACHER, Clóvis M D . Alanine reverses the inhibitory effect of phenylalanine and its metabolites on Na+, K+-ATPase in synaptic plasma membrane from cerebral cortex of rats.. Biochemical Society Transactions, v. 23, p. 227, 1995.
337. MELLO, C. ; SOMMER, J. ; TAVARONI, V. ; GRACIOLLI, R. ; WU, V. ; TORRES, G. ; AGUIAR, C. ; WANNMACHER, Clóvis M D ; WAJNER, M. . Effect of postnatal methylmalonate administration on neurobehavioral development of rats. Brazilian Journal of Medical and Biological Research, v. 27, p. 655-661, 1994.
338. WAJNER, M. ; SOMMER, M. ; WANNMACHER, Clóvis M D . The influence of arginine on in vitro lymphocyte proliferation. Arquivos de Biologia e Tecnologia, v. 37, p. 645-653, 1994.
339. WYSE, Angela ; SARKIS, J. J. F. ; CUNHA FILHO, J. ; TEIXEIRA, M. ; SCHETINGER, M. R. ; WAJNER, M. ; WANMACHER, C. . Effect of phenyllalanine and its metabolites on ATP diphodphohydrolase activity in synaptosomes from rat cerebral cortex. Neurochemical Research, v. 19, p. 1175-1180, 1994.
340. WAJNER, M. ; PASTERNACK, C. ; RANDLE, P. ; MICKLEN, M. ; IZQUIERDO, I. ; SALZANO, F. ; PENA, S. . Biomedicine today and tomorrow. Ciência e Cultura (SBPC), v. 46, p. 201-211, 1994.
341. SOMMER, M. ; XAVIER, M. ; FIALHO, M. B. ; WANNMACHER, Clóvis M D ; WAJNER, M. . The Influence of amino acids on mitogen-activated proliferation of human lymphocytes. International Journal of Immunopharmacology, v. 16, p. 865-874, 1994.
342. WAJNER, M. ; GOLDBECK, A. ; LHULLIER, F. ; C NETTO, ; GIGLIANI, R. . Neonatal Screening for aminoacidopathies and congenital hypothyrodism: a pilot program in southern Brazil. Brazilian Journal of Genetics, v. 17, p. 229-230, 1994.
343. DUTRA, J. C. ; WAJNER, M. ; WANNMACHER, Clóvis M D ; DUTRA FILHO, Carlos Severo ; RACHE, E. . Inhibition of succinate dehydrogenase and beta-hydroxybutyrate dehydrogenase activities by methylmalonate in brain and liver of developing rats.. Journal of Inherited Metabolic Disease, v. 16, p. 147-153, 1993.
344. WAJNER, M. ; DUTRA, J. C. ; WANNMACHER, Clóvis M D ; CARDOSO, S. ; MOTTA, E. . Effect of methylmalonate on in vitro lactate release and co2 production by brain of suckling rats. Journal of Inherited Metabolic Disease, v. 15, p. 92-96, 1992.
345. SOMMER, M. ; XAVIER, M. ; FIALHO, M. B. ; WANNMACHER, Clóvis M D ; WAJNER, M. . Immunomodulatory action of aminno acids on lymphocyte blastogenesis. Biochemical Society Transactions, v. 20, p. 176, 1992.
346. WAJNER, M. ; SANSEVERINO, M. T. ; GIUGLIANI, Roberto ; SWEETMAN, L. ; SHIH, V. . Biochemical Investigation of a brazilian patient with a defect of mitochondrial acetoacetyl-CoA thiolase. Clinical Genetics, v. 41, p. 202-205, 1992.
347. WAJNER, M. ; GIUGLIANI, Roberto ; DUTRA FILHO, Carlos S ; BARTH, M. L. ; GOLDENFUN, S. ; DUTRA, J. . Detection of inborn errors of metabolism in hih-risk patients: 9 year report from a reference center. American Journal of Human Genetics, v. 49, p. 470, 1991.
348. DUTRA, J. C. ; WANNMACHER, C. F. ; DUTRA FILHO, Carlos Severo ; WANNMACHER, Clóvis M D ; WAJNER, M. . Effects of methylmalonate and propionate on glucose and ketone bodies uptake in vitro by brain of developing rats.. Biochemical Medicine And Metabolic Research, v. 45, p. 56-64, 1991.
349. DUTRA, J. C. ; WAJNER, M. ; WANMACHER, C. ; WANNMACHER, L. ; PIRES, R. F. ; ROSA JUNIOR, A. . Effects of postnatal methylmalonate administration on adult rat behavior. Brazilian Journal of Medical and Biological Research, v. 24, p. 595-605, 1991.
350. GIUGLIANI, Roberto ; DUTRA, J. C. ; DUTRA FILHO, Carlos S ; GOLDENFUM, S. ; WAJNER, M. . Seven year experience of a reference laboratory for detection of inborn errors of metabolism in Brazil. Journal of Inherited Metabolic Disease, v. 14, p. 400-402, 1991.
351. WAJNER, M. ; WANNMACHER, C. M. D. ; PURKISS, P. . High Urinary Excretion Of N-(Pyrrole-2-Carboxyl) Glycine In Type Ii Hyperprolinemia.. Clinical Genetics, v. 37, p. 485-489, 1990.
352. DUTRA, J. C. ; WAJNER, M. ; DUTRA FILHO, Carlos S ; WANNMACHER, C. F. ; WANNMACHER, Clóvis M D . Influence of methylmalonate on ketone bodies uptake in vitro by brain of young rats. Biochemical Society Transactions, v. 18, p. 421-422, 1990.
353. RODRIGUES, N. ; WANNMACHER, Clóvis M D ; DUTRA FILHO, Carlos Severo ; PIRES, Ricardo ; FAGAN, P. ; WAJNER, M. . Effect of phenylalanine, p-chlorophenylalanine and alpha-methylphenylalanine on glucose uptake by brain of young rats.. Biochemical Society Transactions, v. 18, p. 419, 1990.
354. MOREIRA, J. C. F. ; WANNMACHER, Clóvis M D ; COSTA, S. M. E. ; WAJNER, M. . Effect Of Proline Administration On Rat Behavior In Aversive And Nonaversive Tasks.. Pharmacology, Biochemistry and Behavior, v. 32, n. 4, p. 885-890, 1989.
355. DUTRA-FILHO, C. S. ; WANNMACHER, Clóvis M D ; PIRES, R. R. ; GUS, G. ; KALIL, A. M. ; WAJNER, M. . Reduced Locomotor Activity Of Rats Made Histidinemic By Injection Of Histidine.. The Journal of Nutrition, v. 119, p. 1223-1227, 1989.
356. WAJNER, M. ; DUTRA, J. C. ; WANNMACHER, C. M. D. . Chemically-Induced Methylmalonic Acidemia For Neurochemical And Behavioral Studies In Rats.. Biochemical Society Transactions, v. 17, p. 572-573, 1989.
357. WAJNER, M. ; HARKNESS, R. A. . Distribution Of Xanthine Dehydrogenase And Oxidase Activities In Human And Rabbit Tissues.. Biochimica et Biophysica Acta. Molecular Basis of Disease, v. 991, p. 79-84, 1989.
358. DUTRA, J. C. ; WAJNER, M. ; WANNMACHER, C. F. . Methylmalonate Increases In Vitro Glucose Uptake By Brain Of Young Rats.. Biochemical Society Transactions, v. 17, p. 571-572, 1989.
359. GIUGLIANI, Roberto ; DUTRA FILHO, Carlos Severo ; PEREIRA, M. ; DUTRA, J. C. ; WAJNER, M. ; WANNMACHER, Clóvis M D ; MONTAGNER, L. . Sensitivity of screening tests for the detection of inborn errors of metabolism. Clinical Pediatrics, v. 28, p. 494-499, 1989.
360. WAJNER, M. ; HARKNESS, R. A. . Distribution Of Xanthine Oxidase And Dehydrogenas Activities In Man And Rabbit Tissues.. Biochemical Society Transactions, v. 16, p. 358-359, 1988.
361. WAJNER, M. ; BRITES, E. C. ; DUTRA, J. C. ; BUCHALTER, M. S. ; PONS, A. H. ; PIRES, R. F. ; WANNMACHER, L. E. ; ROSA JUNIOR, A. ; TRINDADE, V. M. T. . Diminished Concentrations Of Ganglioside N-Acetyl Neuraminic Acid (G-Neuac) In Cerebellum Of Young Rats Receiving Chronic Administration Of Methylmalonic Acid.. Clinical Genetics, v. 85, p. 235-238, 1988.
362. WAJNER, M. . Acidurias orgânicas: diagnóstico e tratamento.. Revista AMRIGS, v. 32, p. 280-282, 1988.
363. WAJNER, M. . Detecção de acidurias orgânicas em crianças severamente enfermas.. Revista Materno Infantil de Ginecologia, v. 8, p. 47-49, 1988.
364. WAJNER, M. ; PAPIHA, S. S. ; WAGSTAFF, T. I. . Relationship Between Immunoglobulin G And Alphafetoprotein In Serum Levels During Human Pregnancy.. Journal of Perinatal Medicine, v. 15, p. 251-257, 1987.
365. WANNMACHER, C. M. D. ; WAJNER, M. ; GAIDZINSKI, D. ; DUTRA FILHO, Carlos S . Detection Of Inborn Errors Of Metabolism In Patients Of Pediatric Infensive Care Units Of Porto Alegre,Brasil. A Critical Analysis Of The Screening Techniques Utilized.. Brazilian Journal of Medical and Biological Research, v. 20, p. 11-23, 1987.
366. WAJNER, M. ; PAPIHA, S. S. ; WAGSTAFF, T. I. . Relationship Between Some Obstetril Landmarks And The Concentration Of Alpha-Fetoprotein In Maternal Blood.. Journal of Perinatal Medicine, v. 14, p. 115-121, 1986.
367. WAJNER, M. ; DUTRA-FILHO, C. S. ; PAPIHA, S. S. . Inhibition Of Lymphocyte Blastogenesis By Serum Between In Vitro Immunosupresion And Alphafetoprotein Levels.. Ciência e Cultura (SBPC), v. 38, p. 678-684, 1986.
368. ARRUDA, N. B. ; WAJNER, M. . The Influence Or Prolactin On The Proliferation Of Unstimulated And Phytohemagglutinin Stimulated Lymphocytes Of Third Trimester Pregnant Females.. Arquivos de Biologia e Tecnologia, v. 29, p. 423-428, 1986.
369. WAJNER, M. ; GAIDZINSKI, D. ; WANNMACHER, Clóvis M D ; FONTANA, M. H. ; CHALMERS, R. A. . Methylmalonic Aciduria Unresponsive To Vitamin B12: Descsiption Of Two Cases And Prenatal Diagnosis.. Molecular Genetics and Metabolism, v. 17, n. 04, p. 694-701, 1986.
370. WAJNER, M. ; PAPIHA, S. S. ; WASTAFF, T. I. . Inhibition Of Mitogen And Allogeneic Stimulated Lymphocyte Growth By Human Amniotic Fluid: Lack Of Correlaction Between Alpha-Fetoprotein Level And In Vitro Immunosupression.. European Journal of Obstetrics, Gynecology, and Reproductive Biology, v. 21, p. 225-232, 1986.
371. WAJNER, M. ; PAPIHA, S. S. . Human Purified Alpha-Fetoprotein: I. In Vitro Proliferation To Mitogens And Mixed Lymphocyte Reactivity.. Ciência e Cultura (SBPC), v. 38, p. 170-178, 1986.
372. WAJNER, M. ; WANNMACHER, Clóvis M D ; GAIDZINSKY, D. ; DUTRA FILHO, Carlos S . Detection Of Inborn Of Metabolism In Of Paediatric Intensive Care Units Of Porto Alegre, Brazil. Comparison Between The Prevalence Of Such Distrubances In A Selected And An Unselected Sample.. Molecular Genetics and Metabolism, v. 17, n. 02, p. 331-340, 1986.
373. WAJNER, M. . Conduta nos defeitos do tubo neural. Revista Materno Infantil de Ginecologia, v. 6, p. 34-37, 1986.
374. WAJNER, M. ; ARRUDA, N. B. . The Influence Of Aldosterone On The Phytohemagglutinin - Induced Lymphocyte Blastogenesis. Revista Brasileira de Biologia, v. 45, p. 557-561, 1985.
375. WAJNER, M. ; PAPIHA, S. S. ; ARRUDA, N. B. . Inhibition Of Pha-Induced Lymphocyte Blastogenesis By Serum Frompregnant Womem: Correlation Between Cortisol Leve And In vitro Immunosupresion.. Acta Endocrinologica, v. 109, p. 411-417, 1985.
376. WAJNER, M. ; BERTACCO, M. . Síndrome de Ellis Vas Crevelt: descrição de um caso.. Revista Materno Infantil de Ginecologia, v. 5, p. 29-31, 1985.
377. WANNMACHER, C. M. D. ; WAJNER, M. ; GIUGLIAN, R. ; GIUGLIANI, E. R. J. ; COSTA, M. G. ; CASTRO, J. Z. . Clinical And Biochemical Effects Of Long Term Vitamin A Administration To A Patient With Hurler-Scheie Compound.. Brazilian Journal of Medical and Biological Research, v. 17, p. 43-47, 1984.
378. WAJNER, M. ; PAPIHA, S. ; WAGSTAFF, T. . Inhibition of lymphocyte transformation by serum from pregnant women: a lack of correlation with levels alpha-fetoprotein. Biology of the Neonate, v. 43, p. 109-117, 1983.
379. WAJNER, M. ; BUCHALTER, M. ; WANNMACHER, Clóvis M D . Tay-sachs heterozygote detection: comparison between tears and leucocytes as b-hexosaminidade a souce . Journal of Inherited Metabolic Disease, v. 7, p. 35-37, 1983.
380. WAJNER, M. ; PAPIHA, S. ; WAGSTAFF, T. . Response of human peripheral blood lymphocytes in the presence of cord blood: relationship of limphocites transformation with number of pregnancies and levels of alpha-fetoprotein.. Clinical and Experimental Immunology, v. 52, p. 381-386, 1983.
381. BUCHALTER, M. ; WANMACHER, C. ; WAJNER, M. . Tay-Sachs disease screening and prevention program in Porto Alegre. Brazilian Journal of Genetics, v. 5, p. 539-547, 1983.
382. WANNMACHER, Clóvis M D ; WAJNER, M. ; DUTRA FILHO, Carlos S ; GIUGLIANI, Roberto . An Improved especific laboratory test for homocystinuria . Clinica Chimica Acta, v. 25, p. 367-369, 1982.
383. WANNMACHER, Clóvis M D ; WAJNER, M. ; GIUGLIANI, Roberto ; COSTA, M. ; GIUGLIANI, E. . Detection of metabolic disorders among high risk patients. Brazilian Journal of Genetics, v. 5, p. 185-194, 1982.
384. WAJNER, M. . Alfafetoproteína: sua biologia e aplicação na prática médica. Revista da Associação Médica Brasileira, v. 28, p. 250-254, 1982.
385. WAJNER, M. ; GIUGLIANI, Roberto ; WANNMACHER, Clóvis M D . Incontinental pigmenti: relato de um caso.. Jornal de Pediatria, v. 51, p. 341-343, 1981.
386. WAJNER, M. ; BERNAL, J. . Alfafetoproteína e sua importância clínica. Revista da Associação Médica Brasileira, v. 24, p. 115-120, 1980.
387. GIUGLIANI, Roberto ; GIUGLIANI, E. ; WAJNER, M. ; WANNMACHER, Clóvis M D . Inborn metabolic errors in visually deficient pacients: efficiency of screening methods.. Brazilian Journal of Genetics, v. 3, p. 179-186, 1980.
388. WAJNER, M. ; WANNMACHER, Clóvis M D . Avaliação de distúrbios metabólicos em deficientes mentais. Revista da Associação da Turma Médica de 1971, v. 1, p. 213-234, 1971.
Capítulos de livros publicados
1. WAJNER, M. ; VARGAS, C. . Aminoacidopatias e Acidemias orgânicas. In: Luiz Fernando Fonseca; Geraldo Pianetti; Cristóvão de Castro Xavier. (Org.). Compêncio de Neurologia Infantil. 1 ed. Rio de Janeiro: Editora Médica e Científica Ltda, 2002, v. 1a edi, p. 589-604.
2. WAJNER, M. ; A NETTO, C. ; VARGAS, Carmen R . Acidúrias orgânicas. In: Gerson Carakushansky. (Org.). Doenças genéticas em pediatria. 1 ed. Rio de Janeiro: Editora Guanabara Koogan, 2001, v. 1a. ed, p. 162-171.
3. M, W. ; WAJNER, M. . Erros Inatos do Metabolismo. In: Renato Dutra Dias; Clóvis Wannmacher. (Org.). Pediatria: Consulta Rápida. 1 ed. Porto Alegre: Artes Médicas, 1995, v. , p. -.
4. WAJNER, M. . Mucopolissacarídeos. In: Paulo Pitrez. (Org.). Pediatria: Consulta Rápida. 1 ed. Porto Alegre: Artes Médicas, 1995, v. , p. -.
5. WAJNER, M. . Quimica e Metabolismo do Dna. In: Clóvis Wannmacher e Renato D. dias. (Org.). BIOQUIMICA FUNDAMENTAL. BRASIL: , 1986, v. , p. 0372-0388.
6. WAJNER, M. . Quimica e Metabolismo do Rna. In: Clóvis Wannmacher e Tenato D. Dias. (Org.). BIOQUIMICA FUNDAMENTAL. BRASIL: , 1986, v. , p. 0389-0403.
Textos em jornais de notícias/revistas
1. BARSCHAK, Alethéa Gatto ; SITTA, Angela A ; DEON, Marion ; Anelise M. de Carvalho ; Christiane Marchesan ; R, Giugliani ; WAJNER, M. ; VARGAS, C. . Biochemical and oxidative stress profiles in patients with maple syrup urine disease during dietary treatment. Acta Bioquímica Clínica Latino Americana.
2. WAJNER, M. ; COELHO, Daniela Moura ; Anderson B. de Oliveira ; Anelise M. de Carvalho ; SCHMITT, Graziela O ; Estela N. B. Busanello ; VARGAS, Carmen Regla . Clinical significance of amino acids in biological fluids. Acta Bioquímica Clínica Latinoamericana.
3. DEON, Marion ; SITTA, Angella ; BARSCHACK, A. ; TERROSO, Thatiana ; PIGATTO, Maiara Cássia ; BARDEN, Amanda T ; Anderson B. de Oliveira ; SCHMITT, Graziela O ; COELHO, Daniella M ; Hector Y. C. Wanderley ; JARDIM, Laura ; GIUGLIANI, Roberto ; WAJNER, M. ; VARGAS, Carmen R . Different X-linked adrenoleukodystrophy phenotypes and oxidative stress. Acta Bioquímica Clínica Latinoamericana.
4. ROSA, Rafael Borba ; DALCIN, Karina Borges ; SCHMIDT, Anna Laura ; PORCIÚNCULA, Lisiane O ; WANNMACHER, Clóvis Milton Duval ; SOUZA, Diogo Onofre ; WAJNER, M. . Effects of glutaric acid on [3H]glutamate uptake and binding to receptors during rat brain development. Acta Bioquímica Clínica Latinoamericana.
5. SCHUCK, Patrícia Fernanda ; CEOLATO, Paula Casagrande ; FERREIRA, Gustavo da Costa ; TONIN, Anelise ; Angela Zanatta ; Fernanda M. Lopes ; LATINI, Alexandra Susana ; WYSE, A. T. ; WAJNER, M. . Evidence that cis-4-decenoic acid alters oxidative stress in the rat brain: relevance for MCAD deficiency. Acta Bioquímica Clínica Latinoamericana.
6. FERREIRA, Gustavo da Costa ; VIEGAS, Carolina Maso ; SCHUCK, Patrícia Fernanda ; TONIN, Anelise ; CEOLATO, Paula Casagrande ; DUTRAFILHO, Carlos Severo ; WAJNER, M. . Evidence that glutaric acids provokes a moderate inhibition of the energy metabolism in the rat brain. Acta Bioquímica Clínica Latinoamericana.
7. VIEGAS, Carolina Maso ; FERREIRA, Gustavo ; SCHUCK, Patrícia Fernanda ; TONIN, Anelise ; CEOLATO, Paula Casagrande ; Angela Zanatta ; SEMINOTTI, Bianca ; DUTRAFILHO, Carlos Severo ; WANNMACHER, Clóvis Milton Duval ; WAJNER, M. . evidence that 3-hydroxisobutiric acid impairs energy metabolism in the brain of young rats. Acta Bioquímica Clínica Latinoamericana.
8. LEIPNITZ, Guilhian ; SEMINOTTI, Bianca ; HAUBRICH, Josué ; BORBA, Rafael Rosa ; SOLANO, Alexandre F ; Geogia Bortoli ; AMARAL, Alexandre ; Fernanda M. Lopes ; DUTRAFILHO, Carlos Severo ; LATINI, Alexandra Susana ; WAJNER, M. . Evidence that 3-hydroxy-3-methylglutaric acid induces oxidative stress in the cerebral cortex of young rats. Acta Bioquímica Clínica Latinoamericana.
9. LOUREIRO, S Oliveira ; LATINI, Alexandra Susana ; Juan Carlos Rosillo ; FERNANDEZ, A. ; Patricia Cassina ; WAJNER, M. ; Luís Barbeito . Glutaric acid induces in vitro and in vivo astrocyte proliferation: a mechanism underlying macrocephaly in glutaric acidemia I?. Acta Bioquímica Clínica Latinoamericana.
10. SCHMIDT, Anna Laura ; FERREIRA, Gustavo da Costa ; AMARAL, Alexandre ; SCHUCK, Patrícia Fernanda ; LATINI, Alexandra Susana ; WAJNER, M. . in vitro effects of methylmalonic and propionic acids in mitochondrial respiration in brain of young rats. Acta Bioquímica Clínica Latinoamericana.
11. SITTA, Angella ; BARSCHACK, A. ; DEON, Marion ; MARI, Jurema F de ; WAJNER, M. ; VARGAS, Carmen R . Lipoperoxidation and serum carnitine levels in phenylketonuric patients under dietary treatment. Acta Bioquímica Clínica Latinoamericana.
12. SCHMITT, Graziela O ; SITTA, Angella ; M, Deon ; BARSCHACK, A. ; COELHO, Daniela M ; Estela N. B. Busanello ; A Buker ; WAJNER, M. ; VARGAS, C. . Lipoperoxidation in patients with desorders of propionate metabolism before and during treatment. Acta Bioquímica Clínica Latinoamericana.
13. LATINI, Alexandra Susana ; SCUSSIATO, Karina ; LEIPNITZ, Guilhian ; FERREIRA, Gustavo da C ; BORBA, Rafael Rosa ; DUTRAFILHO, Carlos Severo ; WAJNER, M. . Mechanisms underlying neurotoxic damage by glutaric acids. Acta Bioquímica Clínica Latinoamericana.
14. WANNMACHER, Clovis Milton Durval ; DUTRAFILHO, Carlos Severo ; WYSE, Angela Terezinha Souza ; LATINI, Alexandra Susana ; WAJNER, M. . Oxidative stress. Acta Bioquímica Clínica Latinoamericana.
Trabalhos completos publicados em anais de congressos
1. FUNCHAL, C ; SANTOS, Aq ; JAQUESSILVA, Mc ; ZAMONER, A ; GOTTFRIED, C ; WAJNER, M. ; PESSOAPUREUR, R . Effect of the branched-chain alpha-keto acids accumulating in maple syrup urine disease on GFAP phosphorilation and reorganization. In: International Congress of Neuchemistry, 2005, 2005. v. 94. p. 93-93.
2. SITTA, Angela ; BARSCHAK, Alethea ; DEON, Marion ; TERROSO, Thatiana ; OLIVEIRA, Marcela H ; BARDEN, Amanda ; DUTRA FILHO, Carlos S ; WAJNER, M. ; VARGAS, Carmen R . Parametros de estresse oxidativo en pacientes con fenilcetonuria bajo tratamento.. In: V Congresso Latinoamericano de Erros Inatos do Metabolismo e pesquisa Neonatal, 2005, San Jose. Anais V Congresso Latinoamericano de Erros Inatos do Metabolismo e pesquisa Neonatal, 2005.
3. LATINI, Alexandra ; SCUSSIATO, Karina ; LEIPNITZ, Guilhian ; WAJNER, M. . Evidence that 3-hydroxiglutaric acid induces oxidative stress in rat brain. In: SFRBM's 10th Annual Meeting, 2003, Seattle. Anais da SFRBM's Annual Meeting, 2003. v. 35. p. 158-159.
4. BRIDI, Raquel ; BRAUN, César ; LATINI, Alexandra ; WAJNER, M. ; DUTRAFILHO, Carlos Severo . Evidence that L-leucine and L-alfa-ketoisocaproic acid induce oxidative stress in rat brain. In: SFRBM's 10th Annual Meeting, 2003, Seattle. Anais de SFRBM's 10th Annual Meeting, 2003. v. 35. p. 155-155.
5. ROSA, Aline M ; FUNCHAL, Cláudia ; VIVIAN, Lilian ; LOUREIRO, Samanta O ; PELAEZ, Priscila de L ; PESSUTTO, Franciele D B ; ALMEIDA, Lúcia M V ; WAJNER, M. ; PUREUR, Regina P . Efeito do ácido alfa-ceto-beta-metilvalérico sobre a fosforilação e a imunoreatividade da subunidade de alto peso molecular (NF-H) dos neurofilamentos de córtex cerebral de ratos. In: XI Congresso Brasileiro de Biologia Celular, 2002, Porto Alegre. Anais do XI Congresso Brasileiro de Biologia Celular, 2002. p. 105-105.
6. FUNCHAL, Cláudia ; PELAEZ, Priscila de L ; LOUREIRO, Samanta O ; VIVIAN, Lilian ; PESSUTTO, Franciele D B ; A, Lúcia M V ; ROSA, Aline M ; WAJNER, M. ; PUREUR, Regina P . Efeitos do ácido alfa-cetoisocapróico e do glutamato sobre a fosforilação in vitro de filamentos intermediários de córtex cerebral de ratos durante o desenvolvimento. In: XI Congresso Brasileiro de Biologia Celular, 2002, Porto Alegre. Anais do XI Congresso Brasileiro de Biologia Celular, 2002. p. 105-105.
7. VILAMIN, I. A. D. ; SILVA, C. G. ; BRUSQUE, A. M. ; WYSE, Angela ; WAJNER, M. . Ácido d-2-hidrxiglutárico como inibidor da atividade da citocromo oxidase cerebral. In: XI Salão VIII Feira de Iniciação Científica, 1999. Porto Alegre RS.
8. WAJNER, M. ; VARGAS, C. ; GIUGLIANI, R ; COELHO, J. ; COSTA, J. ; FUNAYAMA, C. ; ARAÚJO, P. ; PULROLNICK, V. ; FURLANETTO, V. ; BARSCHAK, Alethea G ; CAVALIERI, J. . Aciduria glutarica tipo I : un transtorno mas frecuente de lo que se pensaba previamente. In: II Congresso Latinoamericano de Errores Inatus de Metabolismo, 1999. Santiago - Chile. p. 51-51.
9. WAJNER, M. ; PETTENUZZO, L. ; ARAÚJO, P. ; FURLANETTO, V. ; FONTELA, F. ; SCHWARZBOLD, C. ; VARGAS, C. ; WANNMACHER, Clóvis M D . Acute Administration of leucine diminishes the concentration of the large neural amino acids (Inaa) in plasma of young rats. In: XVII SBBQ, 1999. Caxambu. p. 162.
10. STRACKE, M. P. ; MELLO, C F ; FEKSA, L. ; BRUSQUE, A. M. ; WANNMACHER, Clóvis M D ; WAJNER, M. . Administração crônica de leucina prejudica a habituação a campo aberto em ratos. In: XIV Reunião Anual da FESBE 99, 1999. Caxambu.
11. WAJNER, M. ; WYSE, A. ; PETTERSON, F. ; NORILER, M. ; BORGES, L. ; WANNMACHER, Clóvis M D . Alanine prevents the decrease of Na+, K+- atpase activity in brain of hiperphenil alaninenic rats. In: 37 SSIEM Symposium, 1999. Genova - Itália. p. 54.
12. WAJNER, M. ; MANDELLI, J. ; PIRES, R. ; SWARTZ, I. ; COELHO, J. . Caracterizacion de la alfa-iduronidasa en leucocitos de heterocigotos para la mucopolisacaridosis tipo i scheie. In: II Congresso Latinoamericano de Errores Inatos do Metabolismo, 1999. Santiago - Chile. p. 76.
13. WAJNER, M. T. S. F. M. S. J. E. B. A. D. C. ; WAJNER, M. . Chronic Administration Of Propionic Acid Causes A Reduction Of Gangliosides And Phospholipids Contents In The Rat Brain. In: XXVII Reunião Anual SBBq, 1998. Chronic administration of propionic acid causes a reduction of gangliosides and phospholipids contents in the rat brain. Caxambu, MG.. p. 172.
14. JUNQUEIRA, D. ; WAJNER, M. ; WAJNER, M. S. C. P. L. B. A. W. A. . Chronic Administration Of Methylmalonic Acid Reduces Total Lipids, Gangliosides And Phospholipids Contents In Cerebelum Of Rats. In: XXVII Reunião Anual SBBq, 1998. Chronic administration of methylmalonic acid reduces total lipids, gangliosides and phospholipids contents in cerebelum of rats. Caxambu, MG.. p. 172.
15. WAJNER, M. B. A. R. D. C. T. V. W. C. ; WAJNER, M. . Chronic Administration Of Propionic Acid In Rats Diminishes The Plasma Level Of Cholesterol And Tryglycerides. In: XXVII Reunião Anual SBBQ, 1998. Chronic administration of propionic acid in rats diminishes the plasma level of cholesterol and tryglycerides. Caxambu. p. 172.
16. WAJNER, M. B. A. S. C. S. E. W. C. ; WAJNER, M. ; ATS, W. . Effect Of Chronic Propionate Administration On Na K Atpase Activity From Rat Brain. In: XXVII RA SBBQ, 1998. Effect of chronic propionate administration on Na K ATPase activity from rat brain. Caxambu, MG. p. 172.
17. BURGER, C. ; WAJNER, M. ; WAJNER, M. S. C. ; CMD, W. A. W. . Kinetic Studies Of The Reversion Of The Inhibitory Effect Of Leucine And Phenylalanine On The Brain Na K Atpase. In: XXVII RA SBBq, 1998. Kinetic studies of the reversion of the inhibitory effect of leucine and phenylalanine on the brain Na K ATPase.. Caxambu, MG. p. 172.
18. PAROLO, E. S. C. ; WAJNER, M. ; WAJNER, M. S. E. ; ATS, W. C. W. . Inhibition Of Na K Atpase From Brain Cortex Of Rats By Guanidine Compounds. In: XXVII RA SBBq, 1998. Inhibition of Na K ATPase from brain coretx of rats by guanidine compounds. Caxambu, MG. p. 173.
19. VIEIRA, G. C. A. P. L. ; WAJNER, M. ; DAL-PIZZOL JR, A. ; EMANUELLI, T. ; WAJNER, M. S. . L2 Hidroxiglutaric Acid Increase Glutamate Binding Of Metabotropic Receptors In Brain Of Young Rats. In: XXVII RA SBBq, 1998. L2 hidroxiglutaric acid increases glutamaet binding of metabotropic receptos in brain of young rats. Caxambu, MG. p. 173.
20. NORILER, M. ; WAJNER, M. ; PAROLO, E. B. L. E. P. ; WAJNER, M. S. E. B. A. ; ATS, W. C. W. . In Vivo Effect Of Phenylalanine And Phenylalanine Hidroxilase Inhibitor On Na K Atpase Activity From Cerebral Coretx Of Rats. In: XXVII RA SBBq, 1998. In vivo effect of phenylalanine and phenylalanine hidroxilase inhibitor on Na K ATPase activity from cerebral cortex of rats. Caxambu, MG. p. 173.
21. PIZZOL JR, A. D. ; VIEIRA, G. C. A. P. L. ; EMANUELLI, T. ; WAJNER, M. . Effect Of Glutaric Acid On Glutamate Binding In Synaptic Membranes And Mithocondrial Fraction Of Brain Of Young Rats. In: XXVII RA SBBq, 1998. Effects of glutaric acid on glutamate binding in synaptic membranes and mithocondrial fraction of young rats. Caxambu, MG. p. 173.
22. PULROLNIK, V. ; WAJNER, M. ; WAJNER, M. T. S. F. F. B. A. W. C. ; CS, K. A. D. . Stimulation Of Lipoperoxidation In Brain By Metabolites Accumulating In Methylmalonic An Dpropionic Acidemias. In: XXVII RA SBBq, 1998. Stimulation of lipoperoxidation in brain by metabolites accumulating in methylmalonic and propionic acidemias. Caxambu, MG. p. 163.
23. BEDIN, M. ; PONZI, D. E. C. D. D. ; WAJNER, M. ; CMD, W. A. W. . Effects Of Phenylalanine And Alanine On Na K Atpase Activity In Human Erytrocyte And Platelets Membranes. In: XXVII RA SBBq, 1998. Effects of phenylalanine and alanine on N aK AATPase activity in human erytrocyte and platelet membranes. Caxambu, MG. p. 163.
24. JUNQUEIRA, D. ; WAJNER, M. . Chronic Administration Of Methylmalonic Acid Reduces Total Lipids, Gangliosides And Phospholipids Contents In Cerebelum Of Rats. In: XXVII Reunião Anual SBBq, 1998. Chronic administration of methylmalonic acid reduces total lipids, gangliosides and phospholipids contents in cerebelum of rats. p. 172.
25. WAJNER, M. . Chronic Administration Of Propionic Acid In Rats Diminishes The Plasma Level Of Cholesterol And Tryglycerides. In: XXVII Reunião Anual SBBQ, 1998. Chronic administration of propionic acid in rats diminishes the plasma level of cholesterol and tryglycerides. p. 172.
26. WAJNER, M. ; ATS, W. . Effect Of Chronic Propionate Administration On Na K Atpase Activity From Rat Brain. In: XXVII RA SBBQ, 1998. Effect of chronic propionate administration on Na K ATPase activity from rat brain. p. 172.
27. PAROLO, E. S. C. ; WAJNER, M. ; ATS, W. C. W. . Inhibition Of Na K Atpase From Brain Cortex Of Rats By Guanidine Compounds. In: XXVII RA SBBq, 1998. Inhibition of Na K ATPase from brain coretx of rats by guanidine compounds. p. 173.
28. NORILER, M. ; WAJNER, M. ; PAROLO, E. B. L. E. P. ; ATS, W. C. W. . In Vivo Effect Of Phenylalanine And Phenylalanine Hidroxilase Inhibitor On Na K Atpase Activity From Cerebral Coretx Of Rats. In: XXVII RA SBBq, 1998. In vivo effect of phenylalanine and phenylalanine hidroxilase inhibitor on Na K ATPase activity from cerebral cortex of rats. p. 173.
29. PULROLNIK, V. ; WAJNER, M. ; CS, K. A. D. . Stimulation Of Lipoperoxidation In Brain By Metabolites Accumulating In Methylmalonic An Dpropionic Acidemias. In: XXVII RA SBBq, 1998. Stimulation of lipoperoxidation in brain by metabolites accumulating in methylmalonic and propionic acidemias. p. 163.
30. MICHELIN, K. T. R. T. C. ; WAJNER, M. ; CS, S. D. . The Influence Of Various Organic Acids On Glutamate Uptake Into Brain Synaptic Vesicles. In: XXVII RA SBBq, 1998. The influence of various organic acids on glutamate uptake into brain synaptic vesicles. p. 163.
31. ARAÚJO, P. V. C. C. D. B. A. ; BARSCHAK, A. ; WAJNER, M. . High Incidence Of Glutaric Acidemias In Brazil. In: LAMIN Meeting, 1997. High incidence of glutaric acidemias in Brazil High incidence of glutaric acidemias in Brazil. Havana, Cuba. p. 65.
32. FEKSA, L. T. S. ; WAJNER, M. ; WAJNER, M. B. A. W. C. . Administração Crônica de Leucina Em Ratos Jovens Altera A Habituação Ao Campo Aberto. In: IX Salão de Iniciação Científica, 1997. Administração crônica de leucina em ratos jovens altera a habituação ao campo aberto. Porto Alegre. p. 168.
33. DAL-PIZZOL, A. ; WAJNER, M. ; WAJNER, M. B. A. R. M. T. S. W. C. D. C. . Efeito do Ácido Propiônico Sobre A Produção de Co2 Em Córtex Cerebral de Ratos Jovens. In: IX Salão de IC, 1997. Efeito do ácido propiônico sobre a produção de CO2 em córtex cerebral de ratos jovens. Porto Alegre. p. 193.
34. PULROLNIK, V. ; WAJNER, M. ; RUSCHEL, C. S. A. ; HELEGNA, C. ; WAJNER, M. B. A. ; CS, D. . Efeito dos Ácidos Dl2 Hidroxibutírico e 4 Hidroxibutírico Sobre A Produção de Co2 e A Síntese de Lipídios Em Córtex Cerebral de Ratos Jovens. In: IX SIC, 1997. Efeito dos ácidos DL2 hidroxibutírico e 4 hidroxibutírico sobre a produção de CO2 e a síntese de lipídios em córtex cerebral de ratos jovens. Porto Alegre. p. 193.
35. VARGAS, C. C. A. B. A. ; WAJNER, M. ; WAJNER, M. T. V. W. C. . Efeito da Admininstração Crônica de Propionato Sobre O Conteúdo de Gangliosídios-Nana Em Cérebro de Ratos Jovens. In: IX SIC, 1997. Efeito da administração crônica de propionato sobre o conteúdo de gangliosídios-NANA em cérebro de ratos jovens. Porto Alegre. p. 193.
36. WAJNER, M. S. G. N. F. W. A. ; WAJNER, M. ; CMD, W. . Estudos Experimentais Em Doenças do Ciclo da Uréia: Efeito da Citrulina e da Ornitina Sobre A Na K Atpase de Cérebro de Ratos. In: IX SIC, 1997. Estudos experimentais em doenças do ciclo da uréia: efeito da citrulina e da ornitina sobre a Na/K ATPase de cérebro de ratos. Porto Alegre. p. 194.
37. WAJNER, M. F. C. J. L. P. R. W. R. S. I. V. C. ; WAJNER, M. . Erros Inatos do Metabolismo Em Crianças Com Convulsões. In: IX SIC, 1997. Erros inatos do metabolismo em crianças com convulsões. Porto alegre. p. 282.
38. AINHORN, F. ; ZOMMER, A. P. R. R. L. ; MICHELIN, K. V. J. S. L. ; VARGAS, C. ; WAJNER, M. ; CMD, W. . Administração de Alanina A Pacientes Fenilcetonúricos. In: IX SIC, 1997. Administração de alanina a pacienets a pacientes fenilcetonúricos. Porto Alegre. p. 282.
39. WAJNER, M. R. M. T. S. B. A. W. C. ; WAJNER, M. . Indução da Acidemia Propiônica Ezperimental; Em Ratos Wistar. In: IX SIC, 1997. Indução de acidemia propiônica experimental. Porto Alegre. p. 215.
40. FEKSA, L. S. C. ; WAJNER, M. ; VARGAS, C. T. S. ; FONTELLA, F. ; ARAÚJO, P. ; WAJNER, M. W. C. . Administração Aguda de Leucina Provoca Uma Diminuição Nos Níveis Plasmáticos de Vários Aminoácidos Alifáticos. In: IX SIC, 1997. Administração aguda de leucina provoca uma diminuição nos níveis plasmáticos de vários aminoácidos alifáticos. Porto alegre. p. 216.
41. FEKSA, L. T. S. ; WAJNER, M. . Administração Crônica de Leucina Em Ratos Jovens Altera A Habituação Ao Campo Aberto. In: IX Salão de Iniciação Científica, 1997. Administração crônica de leucina em ratos jovens altera a habituação ao campo aberto. p. 168.
42. RUSCHEL, C. ; HELEGNA, C. S. A. ; WAJNER, M. ; CS, D. . Inibição In Vitro do Catabolismo de Citrato Pelos Ácidos Dl2 Hidroxibutírico e 4 Hidroxibutírico Em Mitocôndria de Cérebro de Ratos Jovens. In: IX SIC, 1997. Inibição in vitro do catabolismo de citrato pelos ácidos DL2 hidroxibutírico e 4 hidroxibutírico em miticôndria de cérebro de ratos jovens. p. 194.
43. WAJNER, M. . Erros Inatos do Metabolismo Em Crianças Com Convulsões. In: IX SIC, 1997. Erros inatos do metabolismo em crianças com convulsões. p. 282.
44. WAJNER, M. . Indução da Acidemia Propiônica Ezperimental; Em Ratos Wistar. In: IX SIC, 1997. Indução de acidemia propiônica experimental. p. 215.
45. FEKSA, L. S. C. ; WAJNER, M. ; VARGAS, C. T. S. ; FONTELLA, F. ; ARAÚJO, P. . Administração Aguda de Leucina Provoca Uma Diminuição Nos Níveis Plasmáticos de Vários Aminoácidos Alifáticos. In: IX SIC, 1997. Administração aguda de leucina provoca uma diminuição nos níveis plasmáticos de vários aminoácidos alifáticos. p. 216.
46. MATTOSDUTRA, A. ; FREITAS, M. ; SCHROEDER, N. ; WAJNER, M. ; PUREUR, R. . Effect of propionic and methylmalonic acids on the in vitro phosphorylation of cytoskeletal proteins from cerebral cortex of rats. In: XVIa. Reunião Anual da SBBq, 1997, Caxambu. Anais de Congresso, 1997. p. 148.
47. WAJNER, M. ; VARGAS, Carmen ; COELHO, Daniela ; ARAÚJO, P. . Detection of organic acidemias in Brazil. In: LAMIN Meeting, 1997, Havana, 1997. p. 13.
Resumos publicados em anais de congressos
1. MOURA, A P ; ZANATTA, A. ; BUSANELLO, E. N. B. ; Tonin, AM ; RIBEIRO, C. A. J. ; WAJNER, M. . Evidence that 3-Methylcrotonylglycine Disrupts Energy Metabolism in the Brain. In: XL Annual Meeting of SBBq, 2011, Foz do Iguaçu. XL Annual Meeting of SBBq, 2011.
2. HICKMANN, F. ; ZANATTA, A. ; RIBEIRO, C. A. J. ; WAJNER, M. . Evidence that neuroinflammation associated to high brain levels of isovaleric acid induce lipid oxidation and reduce creatine kinase activity in striatum of young rats. In: XL Annual Meeting of SBBq, 2011, Foz do Iguaçu. XL Annual Meeting of SBBq, 2011.
3. KNEBEL, L. A. ; SEMINOTTI, Bianca ; FERNANDES, C. G. ; AMARAL, A. U. ; ROSA, M. S. ; Eichler, P ; LEIPNITZ, Guilhian ; WAJNER, M. . Glycine in vivo Administration Induces Oxidative Stress in Rat Striatumi. In: XL Annual Meeting of SBBq, 2011, Foz do Iguaçu. XL Annual Meeting of SBBq, 2011.
4. FERNANDES, C. G. ; SEMINOTTI, Bianca ; Borges, C. G. ; AMARAL, A. U. ; KNEBEL, L. A. ; ROSA, M. S. ; Eichler, P ; CECCATTO, C. ; LEIPNITZ, Guilhian ; WAJNER, M. . Experimental Evidence that Methylmalonic Acid Induces Oxidative Stress in Neuronal Cells and Striatum of Young Rats. In: XL Annual Meeting of SBBq, 2011, Foz do Iguaçu. XL Annual Meeting of SBBq, 2011.
5. ZANATTA, A. ; BUSANELLO, E. N. B. ; Tonin, AM ; VIEGAS, C M ; MOURA, A P ; GRINGS, M. ; Eichler, P ; WAJNER, M. . In vitro evidence that pristanic acid compromises importat parameters of energy metabolism. In: XL Annual Meeting of SBBq, 2011, Foz do Iguaçu. Caderno de resumos da SBBq, 2011.
6. BUSANELLO, E. N. B. ; Tonin, AM ; AMARAL, A. U. ; Moura, Alana Pimentel ; GRINGS, M. ; VARGAS, C. ; WAJNER, M. . NEUROCHEMICAL EVIDENCE THAT PRISTANIC ACID DISRUPTS MITOCHONDRIAL HOMEOSTASIS IN BRAIN OF YOUNG RATS. In: SSIEM Annual Symposium 2011, 2011, Genebra. Journal of Inherited Metabolic Disease, 2011. v. 34. p. 170.
7. Moura, Alana Pimentel ; ZANATTA, A. ; Tonin, AM ; BUSANELLO, E. N. B. ; GRINGS, M. ; KNEBEL, L. A. ; LOBATO, V. A. G. ; LEIPNITZ, Guilhian ; RIBEIRO, C. A. J. ; WAJNER, M. . 3-METHYLCROTONYLGLYCINE INDUCES LIPID AND PROTEIN OXIDATIVE DAMAGE IN BRAIN OF YOUNG RATS. In: SSIEM Annual Symposium 2011, 2011, Genebra. Journal of Inherited Metabolic Disease, 2011. v. 34. p. 143.
8. SEMINOTTI, Bianca ; KNEBEL, L. A. ; FERNANDES, C. G. ; AMARAL, A. U. ; ROSA, M. S. ; Eichler, P ; LEIPNITZ, Guilhian ; WAJNER, M. . IN VIVO EVIDENCE THAT RAT BRAIN EXPOSED TO HIGH GLYCINE CONCENTRATIONS IS SUSCEPTIBLE TO OXIDATIVE DAMAGE. In: SSIEM Annual Symposium 2011, 2011, Genebra. Journal of Inherited Metabolic Disease, 2011. v. 34. p. 83.
9. Tonin, AM ; MOURA, A P ; ZANATTA, A. ; BUSANELLO, E. N. B. ; GRINGS, M. ; HICKMANN, F. ; RIBEIRO, C. A. J. ; WAJNER, M. . MITOCHONDRIAL BIOENERGETICS, CELLULAR ENERGY TRANSFER AND Na+,K+-ATPase ACTIVITY ARE COMPROMISED BY 3-METHYLCROTONYLGLYCINE IN BRAIN OF YOUNG RATS. In: SSIEM Annual Symposium 2011, 2011, Genebra. Journal of Inherited Metabolic Disease, 2011. v. 34. p. 144.
10. BUSANELLO, E. N. B. ; Tonin, AM ; VIEGAS, Carolina Maso ; MOURA, A P ; GRINGS, M. ; Eichler, P ; VARGAS, C. ; WAJNER, M. . INHIBITION OF NA+,K+-ATPASE ACTIVITY AND MITOCHONDRIAL RESPIRATION BY PRISTANIC ACID IN DEVELOPING RAT BRAIN. In: SSIEM Annual Symposium 2011, 2011, Genebra. Journal of Inherited Metabolic Disease, 2011. v. 34. p. 171.
11. SEMINOTTI, Bianca ; FERNANDES, C. G. ; AMARAL, A. U. ; ROSA, M. S. ; Borges, C. G. ; Braga, LM ; OLIVEIRA, S. ; LEIPNITZ, Guilhian ; Luís Barbeito ; SOUZA, D. O. G. ; Wootner M ; GOODMAN, S. I. ; WAJNER, M. . LYSINE ADMINISTRATION PROMOTES OXIDATIVE STRESS IN BRAIN OF GLUTARYL-COA DEHYDROGENASE-DEFICIENT (Gcdh-/-) MICE. In: SSIEM Annual Symposium 2011, 2011, Genebra. Journal of Inherited Metabolic Disease, 2011. v. 34. p. 139.
12. AMARAL, A. U. ; CECCATTO, C. ; BUSANELLO, E. N. B. ; RIBEIRO, C. A. J. ; LEIPNITZ, Guilhian ; WAJNER, M. . SUCCINATE-SUPPORTED OXYGEN CONSUMPTION IS COMPROMISED BY ETHYLMALONIC ACID PROBABLY BY INTERFERING WITH INTRA MITOCHONDRIAL SUCCINATE TRANSPORT. In: SSIEM Annual Symposium 2011, 2011, Genebra. Journal of Inherited Metabolic Disease, 2011. v. 34. p. 141.
13. Oliveira S ; Cóppola V ; Trías E ; LEIPNITZ, Guilhian ; RIBEIRO, C. A. J. ; GOODMAN, S. I. ; WAJNER, M. ; Luís Barbeito . LYSINE AND GLUTARIC ACID AFFECTS CULTURED ASTROCYTES FROM THE KNOCKOUT MOUSE MODEL OF GLUTARIC ACIDEMIA TYPE I. In: SSIEM Annual Symposium 2011, 2011, Genebra. Journal of Inherited Metabolic Disease, 2011. v. 34. p. 140.
14. SITTA, Â. ; BIANCINI, G.B. ; Wayhs, CAY ; RIBAS, G. S. ; L, Giugliani ; Pereira, IN ; Cirne, C. ; SCHWARTZ, I. ; Borer D ; GARCIA, S. C. ; WAJNER, M. ; CR, V. . Beneficial effect of L-carnitine and selenium supplementation on oxidative stress in phenylketonuric patients. In: SSIEM Annual Symposium 2011, 2011, Genebra. Journal of Inherited Metabolic Disease, 2011. v. 34. p. 103.
15. MORAES, Tarsila B. ; GR, Dalazen ; TERRA, M. ; Jacques, CED ; PICCOLI, B. L. ; WAJNER, M ; DUTRA FILHO, . Glutathione neurometabolism evaluation in a model of hyperphenylalaninemia in rats. In: SSIEM Annual Symposium 2011, 2011, Genebra. Journal of Inherited Metabolic Disease, 2011. v. 34. p. 104.
16. MATTÉ, Cristiane ; SANTOS, T. M. ; MACKEDANZ, V. ; STEFANELLO, F. M. ; WAJNER, M. ; CDM, W. ; ATS, W. . Hyperhomocysteinemia modulates cytochrome C oxidase activity in parietal cortex of rats: neuroprotective role of folic acid. In: SSIEM Annual Symposium 2011, 2011, Genebra. Journal of Inherited Metabolic Disease, 2011. v. 34. p. 112.
17. Ribas GC ; Manfredini, V. ; de Marco, Maria Gilda ; Vieira, Rosana B. ; Wayhs, CAY ; RODRIGUES, D. G. ; KOLHRAUSCH, J. S. ; WAJNER, M. ; VARGAS, C. . DNA damage induced by propionic and L-methylmalonic acids in human peripheral leukocytes in vitro is prevented by L-carnitine. In: SSIEM Annual Symposium 2011, 2011, Genebra. Journal of Inherited Metabolic Disease, 2011. v. 34. p. 137.
18. Knebel, Lisiane Aurélio ; ZANATTA, A. ; GRINGS, M. ; A, Tonin ; Moura, Alana Pimentel ; ALVORCEM, L. M. ; WAJNER, M. ; G, Leipnitz . Induction of oxidative stress by 2-methylbutyrylglycine in rat brain. In: SSIEM Annual Symposium 2011, 2011, Genebra. Journal of Inherited Metabolic Disease, 2011. v. 34. p. 141.
19. GUILHIAN, L. ; Amaral, Alexandre Umpierrez ; SEMINOTTI, Bianca ; FERNANDES, C. G. ; KNEBEL, L. A. ; ZANATTA, A. ; CVARGAS, C. R. ; WAJNER, M. . Evidence that pristanic acid induces lipid and protein oxidative damage and reduces non-enzymatic antioxidant defenses in rat brain. In: SSIEM Annual Symposium 2011, 2011, Genebra. Journal of Inherited Metabolic Disease, 2011. v. 34. p. 171.
20. PIRES, R. F. ; GOLDIN, M. S. P. ; ANDRADE, C. V. ; COELHO, J. C. ; WAJNER, M. . Correlation between sphingomyelinase, beta-glucosidase, beta-galactosidase and hitotriosidase activity among niemann-pick type C patients and normal subjects. In: SSIEM Annual Symposium 2011, 2011, Genebra. Journal of Inherited Metabolic Disease, 2011. v. 34. p. 192.
21. ZANATTA, A. ; Moura, Alana Pimentel ; Tonin, AM ; BUSANELLO, E. N. B. ; GRINGS, M. ; KNEBEL, L. A. ; RIBEIRO, C. A. J. ; Lobato, V ; G, Leipnitz ; WAJNER, M. . Induction of lipid and protein oxidative damage by 3-methylcrotonylglycine in cerebral cortx of developing rats. In: VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011, Cusco. VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011.
22. MOURA, A P ; ZANATTA, A. ; BUSANELLO, E. N. B. ; Tonin, AM ; GRINGS, M. ; HICKMANN, F. ; RIBEIRO, C. A. J. ; WAJNER, M. . 3-Methylcrotonylglycine compromises brain energy metabolism of young rats: a possible pathomechanism of brain damage in 3-methycrotonyl-CoA carboxylase deficiency. In: VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011, Cusco. VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011.
23. SEMINOTTI, Bianca ; FERNANDES, C. G. ; ROSA, M. S. ; AMARAL, A. U. ; Borges, C. G. ; Braga, LM ; Oliveira S ; LEIPNITZ, Guilhian ; Luís Barbeito ; SOUZA, D. O. G. ; Wootner M ; GOODMAN, S. I. ; WAJNER, M. . Induction of oxidative stress in brain of glutaryl-CoA dehydrogenase-deficient (Gcdh -/-) mice by lysine injection. In: VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011, Cusco. VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011.
24. KNEBEL, L. ; Tonin, AM ; ZANATTA, A. ; GRINGS, M. ; Moura, Alana Pimentel ; ALVORCEM, L. M. ; WAJNER, M. ; G, Leipnitz . Oxidative stress is elicited by 2-methylbutyrylglycine in rat brain. In: VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011, Cusco. VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011.
25. BUSANELLO, E. N. B. ; Tonin, AM ; VIEGAS, Carolina Maso ; MOURA, A P ; GRINGS, M. ; Eichler, P ; VARGAS, C. ; WAJNER, M. . Pristanic acid reduces electron flow through the respiratory chain and Na+,K+ ATPase actiivity in brain from young rats. In: VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011, Cusco. VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011.
26. BUSANELLO, E. N. B. ; Tonin, AM ; AMARAL, A. U. ; VIEGAS, Carolina Maso ; MOURA, A P ; GRINGS, M. ; Eichler, P ; VARGAS, C. ; WAJNER, M. . Disruption of mitochondrial homeostasis by pristanic acid in the brain. In: VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011, Cusco. VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011.
27. SEMINOTTI, Bianca ; KNEBEL, L. A. ; FERNANDES, C. G. ; AMARAL, A. U. ; ROSA, M. S. ; Eichler, P ; LEIPNITZ, Guilhian ; WAJNER, M. . Glycine intraestrial administration provokes oxidative damage in rat brain. In: VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011, Cusco. VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011.
28. AMARAL, A. U. ; CECCATTO, C. ; BUSANELLO, E. N. B. ; RIBEIRO, C. A. J. ; LEIPNITZ, Guilhian ; CASTILHO, R F ; WAJNER, M. . Experimental evidence that ethylmalonic acid interferes with succinate transport into mitochondria in rat brain. In: VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011, Cusco. VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011.
29. GUILHIAN, L. ; AMARAL, A. U. ; SEMINOTTI, Bianca ; FERNANDES, C. G. ; KNEBEL, L. A. ; ZANATTA, A. ; VARGAS, C. ; WAJNER, M. . Neurochemical evidence that oxidative stress induced by pristanic acid may represent a pathomechanism for the brain damage in peroxisomal disorders. In: VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011, Cusco. VIII Congreso Latinoamericano de Errores Innatos del Metabolismo Y Pesquisa Neonatal, 2011.
30. ROCHI, N. ; BENEDET, J. ; TEODORAK, B. P. ; SCAINI, G. ; FERREIRA, G C ; WAJNER, M. ; SCHUCK, P ; STRECK, E. . Tyrosine acute administration inhibited of mitochondrial respiratory chain in cerebral cortex and liver of young rats. In: XXXIX Annual Meeting of SBBq, 2010, Foz do Iguaçu. XXXIX Annual Meeting of SBBq, 2010.
31. AMARAL, A. U. ; LEIPNITZ, G ; FERNANDES, C. G. ; SEMINOTTI, B ; FSCHUCK, P. ; SCHUCK, P. ; ZANATTA, A. ; WAJNER, M . a-ketoisocaproico acid and leucine provoke mitochondrial bioenergetic dysfunction in rat brain. In: XXXIX Annual Meeting of SBBq, 2010, Foz do Iguaçu. XXXIX Annual Meeting of SBBq, 2010.
32. SCAINI, G. ; FERREIRA, G C ; WAJNER, M ; SCHUCK, P F ; STRECK, E. . Inhibition of respiratory chain in cerebral cortex and liver of rats caused by medium-chain fatty acids accumulating in MCAD deficiency. In: XXXIX Annual Meeting of SBBq, 2010, Foz do Iguaçu. XXXIX Annual Meeting of SBBq.
33. SCHUCK, P F ; FELISBERTO, F. ; SIMON, K. R. ; VARELA, A. G. ; TONIN, Anelise ; VIEGAS, C M ; FERREIRA, G C ; PETRONILHO, F. ; DAL-PIZZOL, F. ; WAJNER, M ; STRECK, E. . Acute renal failure potentiates brain DNA damage caused by methylmalonic acid administration in young rats. In: XXXIX Annual Meeting of SBBq, 2010, Foz do Iguaçu. XXXIX Annual Meeting of SBBq, 2010.
34. ZANATTA, A. ; LEIPNITZ, G ; SEMINOTTI, B ; AMARAL, A. U. ; FERNANDES, C. G. ; KNEBEL, L. ; WAJNER, M . Pristanic acid induces oxidative stress in rat brain. In: XXXIX Annual Meeting of SBBq, 2010, Foz do Iguaçu. XXXIX Annual Meeting of SBBq, 2010.
35. FERREIRA, G C ; VIEGAS, C M ; BUSANELLO, E. N. B. ; TONIN, A ; MOURA, A P ; SCHUCK, P F ; WAJNER, M . Impairment of citric acid cycle function caused by medium-chain fatty acids accumulating in MCAD deficiency. In: XXXIX Annual Meeting of SBBq, 2010, Foz do Iguaçu. XXXIX Annual Meeting of SBBq, 2010.
36. SEMINOTTI, B ; TONIN, A ; FERNANDES, C. G. ; AMARAL, A. U. ; ZANATTA, A. ; LEIPNITZ, G ; WAJNER, M . Oxidative damage and disturbance of brain bioenergetics caused by lysine. In: XXXIX Annual Meeting of SBBq, 2010, Foz do Iguaçu. XXXIX Annual Meeting of SBBq, 2010.
37. LEIPNITZ, G ; BUSANELLO, E. N. B. ; VIEGAS, C M ; ZANATTA, A. ; MOURA, A P ; AMARAL, A. U. ; SCHUCK, P F ; WAJNER, M . Dual mechanism of brain damage induced by phytanic acid. In: XXXIX Annual Meeting of SBBq, 2010, Foz do Iguaçu. XXXIX Annual Meeting of SBBq, 2010.
38. GRINGS, M. ; TONIN, A ; FERREIRA, G C ; SCHUCK, P F ; VIEGAS, C M ; BUSANELLO, E. N. B. ; WAJNER, M . Accumulating metabolites in 3-hydroxy long chain acyl-CoA dehydrogenase and mitochondrial trifunctional protein deficiencies disturb mitochondrial energy homeostasis in rat brain. In: XXXIX Annual Meeting of SBBq, 2010, Foz do Iguaçu. XXXIX Annual Meeting of SBBq, 2010.
39. HICKMANN, F. ; RIBEIRO, C. ; WAJNER, M . 3-methylglutaric acid induces reactive species production and compromises energy metabolism in synaptosomes frm cerebral cortex of young rats. In: XXXIX Annual Meeting of SBBq, 2010, Foz do Iguaçu. XXXIX Annual Meeting of SBBq, 2010.
40. BUSANELLO, E ; MOURA, A P ; ZANATTA, A. ; VIEGAS, C M ; FERREIRA, G C ; SCHUCK, P F ; WAJNER, M . Experimental evidence that glycine impairs energy metabolism in the brain of young rats. In: XXXIX Annual Meeting of SBBq, 2010, Foz do Iguaçu. XXXIX Annual Meeting of SBBq, 2010.
41. VIEGAS, Carolina Maso ; BUSANELLO, E. N. B. ; FERREIRA, Gustavo C ; MOURA, A P ; Tonin, AM ; GRINGS, M. ; RITTER, L. ; SCHUCK, Patricia Fernanda ; WYSE, Â. T. S. ; WAJNER, M. . In vivo intracerebroventricular administration of ornithine and homocitrulline inhibits mitochondrial energy production and induce oxidative stress in cerebral cortex of young rats. In: SSIEM Annual Symposium, 2010, Istambul. Journal of Inherited Metabolic Disease, 2010. v. 33. p. 21-21.
42. SEMINOTTI, Bianca ; FERNANDES, C. G. ; AMARAL, A. U. ; ZANATTA, A. ; LEIPNITZ, Guilhian ; DUTRA FILHO, C. S. ; WAJNER, M. . Intrastriatal administration of lysine induces oxidative and bioenergetics damage in striatum of developing rats. In: SSIEM Annual Symposium Istanbul 2010, 2010, Istambul. Journal of Inherited Metabolic Disease, 2010. v. 33. p. 21-21.
43. AMARAL, A. U. ; LEIPNITZ, Guilhian ; FERNANDES, C. G. ; SEMINOTTI, Bianca ; SCHUCK, Patricia Fernanda ; ZANATTA, A. ; Eichler, P ; CECCATTO, C. ; DUTRA FILHO, Carlos Severo ; WAJNER, M. . Neurochemical evidence that the major metabolites accumulating in maple syrup urine disease disturb mitochondrial bioenergetic in brain of young rats. In: SSIEM Annual Symposium Istanbul 2010, 2010, Istambul. Journal of Inherited Metabolic Disease, 2010. v. 33. p. 22-22.
44. FERREIRA, A. G. K. ; STEFANELLO, F. M. ; AA, Cunha ; MJ, da Cunha ; TCB, Pereira ; CD, Bonan ; MR, Bogo ; A NETTO, C ; WAJNER, M. ; WYSE, Â. T. S. . Na+,K+ ATPase activity and gene expression in rats subjected to experimental hyperprolinemia. In: SSIEM Annual Symposium Istanbul 2010, 2010, Istambul. Journal of Inherited Metabolic Disease, 2010. v. 33. p. 22-22.
45. AA, Cunha ; MJ, da Cunha ; FR, Machado ; WAJNER, M. ; WYSE, Â. T. S. . Acute hyperhomocysteinemia alters platelets count and blood coagulations system in rats. In: SSIEM Annual Symposium Istanbul 2010, 2010, Istambul. Journal of Inherited Metabolic Disease, 2010. v. 33. p. 34-34.
46. FR, Machado ; FERREIRA, A. G. K. ; AA, Cunha ; MJ, da Cunha ; B, Mussulini ; WOFCHUK, Susana ; WAJNER, M. ; WYSE, Â. T. S. . Effect fo chronic hyperhomocysteinemia on Na+,K+ ATPase activity and glutamate uptake in hippocampus of rats. In: SSIEM Annual Symposium Istanbul 2010, 2010, Istambul. Journal of Inherited Metabolic Disease, 2010. v. 33. p. 34-34.
47. RIBAS, G. S. ; SITTA, Â. ; Manfredini, V. ; WAYHS, C. Y. ; VANZIN, C.S. ; BIANCINI, G.B. ; WAJNER, M. ; VARGAS, C. . Lipoperoxidation in patients with disorders of propionate metabolism in prevented by treatment with L-carnitine. In: SSIEM Annual Symposium Istanbul 2010, 2010, Istambul. Journal of Inherited Metabolic Disease, 2010. v. 33. p. 38-38.
48. FERNANDES, C. G. ; CG, Borges ; SEMINOTTI, Bianca ; AMARAL, A. U. ; LEIPNITZ, Guilhian ; ZANATTA, A. ; WANNMACHER, Clóvis M D ; WAJNER, M. . Neurochemical evidence that methylmalonic acid elicits lipid and protein oxidative damage in vitro and ex vivo in brain of young rats. In: SSIEM Annual Symposium Istanbul 2010, 2010, Istambul. Journal of Inherited Metabolic Disease, 2010. v. 33. p. 41-41.
49. RIBEIRO, C. A. J. ; HICKMANN, F. ; VARGAS, C. ; WYSE, Â. T. S. ; WAJNER, M. . Inhibition of Na+,K+ ATPase activity in synaptossomes from cerebral cortex of young rats by 3-methylglutaric acid. In: SSIEM Annual Symposium Istanbul 2010, 2010, Istambul. Journal of Inherited Metabolic Disease, 2010. v. 33. p. 47-47.
50. VARELA, A. G. ; SIMON, K. R. ; FELISBERTO, F. ; TONIN, Anelise ;